Cresols
BIOHIPPO h/m MSN shRNA Set GFP Puro
h/m MSN shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated MSN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse Moesin (MSN) The shRNA has been validated to meet or exceed 70% MSN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m NRP1-sh-GFP-BSD
h/m NRP1-sh-GFP-BSD shRNA lentiviral vector expressing GFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m KLF5-sh-GFP-Puro
h/m KLF5-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m KLF5 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse KLF transcription factor 5 (KLF5) The shRNA has been validated to meet or exceed 70% knockdown of KLF5 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC 4-Chloro-2-methylphenol-d4 (4-chloro-o-cresol-d4) | 1219804-06-4 | 99.6% | 146.61 | 50 MG
4-Chloro-2-methylphenol-d4 is a deuterium-labeled version of 4-Chloro-2-methylphenol. It is intended for research use only and is not sold to patients. This compound can be used as a tracer and as an internal standard for quantitative analysis by methods such as NMR, GC-MS, or LC-MS. Deuterium substitution, as seen in this compound, has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer.
- Functions as an internal standard for quantitative analysis.
- Stable heavy isotope.
BIOHIPPO TetOn h/m P53-sh-BSD
TetOn h/m P53-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m MCL1-sh-GFP/Luc
h/m MCL1-sh-GFP/Luc shRNA lentiviral vector expressing GFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human/mouse MCL1 shRNA lentivirus High-titer shRNA lentiviral particles specific for human/mouse MCL1 apoptosis regulator BCL2 family member (MCL1) The shRNA has been validated to meet or exceed 70% MCL1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
BIOHIPPO h/m FASN-sh-GFP-BSD
h/m FASN-sh-GFP-BSD shRNA lentiviral vector expressing GFP with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FASN shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse fatty acid synthase (FASN) The shRNA has been validated to meet or exceed 70% FASN knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Medchemexpress LLC 2-(2,3,4,5,6-pentadeuteriopyridin-1-ium-1-yl)acetohydrazide; chloride | 1505505-87-2 | 99.9% | 192.66 | C7H5D5ClN3O | 25mg
Girard s Reagent P-d5 is a deuterated labeled Girard s Reagent P-d5[1]
Medchemexpress LLC N-(p-Coumaroyl) Serotonin | 68573-24-0 | 99.0% | 50 MG
N-(p-Coumaroyl) Serotonin is a selective inhibitor of PDGFRβ, ERK1/2, and caspase-8, exhibiting antioxidant, anti-atherosclerotic, and anti-inflammatory properties. It inhibits glioblastoma cells and demonstrates anti-inflammatory activity in RAW264.7 cells. The compound works by inhibiting PDGF signaling, blocking Ca2+ influx, and inducing apoptosis, making it suitable for glioblastoma and atherosclerosis research.
- Selective inhibitor of PDGFRβ, ERK1/2, and caspase-8
- Possesses antioxidant, anti-atherosclerotic, and anti-inflammatory properties
- Inhibits glioblastoma cells
- Reduces PDGF signaling and blocks Ca2+ influx
- Induces apoptosis through caspase-8 activation
- Improves atherosclerosis and aortic wall enlargement
eMolecules 20734-74-1 | Ambeed | 5-Methoxy-2-methylphenol | 1g | 525168609 | A278327 | MFCD12405727 | 138.166 | C8H10O2
Ambeed | (2S3R4S5S6R)-2-(4-((E)-35-Dimethoxystyryl)phenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-345-triol | 1g | 649268962 | A1380614 | 38967-99-6 | 418.442 | C22H26O8
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TARGETMOL CHEMICALS INC SPHINX31 25MG
Also available in 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50 5.9 nM). purity: 99%
Apexbio Technology LLC DiscoveryProbe™ Anti-cancer Compound Library Plus 100uL/well(10 mM solution),96 Well Deep Well Plate
DiscoveryProbe Anti-cancer Compound Library comprises 1 164 bioactive compounds targeting multiple oncological pathways with documented activity against cancers including leukemia lymphoma lung and breast cancer The library integrates compounds approved by globally recognized regulatory authorities such as FDA and EMA as well as preclinical candidates extensively documented in oncology research Compounds are selected based on clearly-defined mechanisms including kinase inhibition apoptosis induction cell-cycle regulation and epigenetic modulation Representative agents within the library include Paclitaxel Imatinib Sorafenib and Vorinostat This library is suitable for cancer biology research mechanism-of-action studies drug repurposing screening and preliminary evaluations in therapeutic development contexts