Cresols
Apexbio Technology LLC EZ Cap Mouse IL-23 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-23 mRNA (Interleukin-23) encodes IL-12 cytokine It consists of two subunits IL-23 p19 and IL-12 p40 IL-23 binds to its specific receptor IL-23R activating downstream signaling pathways including the JAK-STAT pathway thus promoting inflammatory responses IL-23 is a potential therapeutic target for various diseases including psoriasis Crohn s disease and multiple sclerosis In recent years biological agents targeting IL-23 such as monoclonal antibodies have been developed for clinical application showing good efficacy and safety EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Apexbio Technology LLC EZ Cap Mouse CD86 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse CD86 mRNA encodes CD86P primarily expressed on antigen-presenting cells It binds to CD28 and CTLA-4 receptors on T cells to regulate T-cell activation and immune responses The interaction between CD86 and CD28 promotes T-cell activation and proliferation whereas its binding to CTLA-4 inhibits T-cell activity maintaining immune system balance Expression and function of CD86 are critical in various immune responses including infections tumor immunity and autoimmune diseases CD86 activity may offer novel therapeutic strategies for various immune-related disorders EZ Cap Mouse CD86 mRNA (m1 HA tag) is provided at 1 mg/mL expressing mouse-derived CD86 cytokine fused with HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Cell Signaling Technology Phospho-CSF-1R/M-CSF-R (Tyr723) (49C10) Rabbit mAb 20 ul
Phospho-CSF-1R/M-CSF-R (Tyr723) (49C10) Rabbit mAb 20 ul
Medchemexpress LLC P-CAB agent 2 | 1978371-23-1 | 98.0% | 432.51 g/mol | C22H25FN2O4S | 10 MG
P-CAB agent 2 is a potent, orally active potassium-competitive acid blocker provided as a research reagent for preclinical studies. It inhibits gastric H+/K+-ATPase with sub-100 nM potency and has reported activity in models of histamine-induced gastric acid secretion.
- Potent H+/K+-ATPase inhibitor (IC50 <100 nM).
- Orally active in preclinical models and inhibits histamine-induced gastric acid secretion.
- Documented 98.0% purity suitable for research applications.
- Analytical characterization available: COA, HNMR, LCMS, and SDS.
- Provided in milligram-scale quantities for in vitro and in vivo studies.
- Soluble in DMSO for assay preparation.
Medchemexpress LLC AMG-108 1mg | 1mg
AMG-108 is a humanized antibody expressed in CHO cells targeting IL-1R1/CD121a AMG-108 is composed of a huIgG2 heavy chain and a hu light chain with a predicted molecular weight (MW) of 144 62 kDa The isotype control for AMG-108 can refer to Human IgG2 kappa Isotype Control (HY-P99002)
Cell Signaling Technology Phospho-(Ser) 14-3-3 Binding Motif (4E2) Mouse mAb 20 ul
Phospho-(Ser) 14-3-3 Binding Motif (4E2) Mouse mAb 20 ul
Cell Signaling Technology FKBP1A/FKBP12 (E8H7Y) Rabbit mAb 20 ul
FKBP1A/FKBP12 (E8H7Y) Rabbit mAb 20 ul
eMolecules 4-Amino-o-cresol | 2835-96-3 | MFCD00007878 | 1g
Oakwood Chemical | 4-Amino-o-cresol | 1g | 537693891 | 046721 | | 2835-96-3 | MFCD00007878 | 123.155 | C7H9NO
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Cambridge Isotope Laboratories 5-Isopropyl-2-methylphenol (isopropyl-13C3 99%) 1 mg/mL in methanol 1 2 mL
5-Isopropyl-2-methylphenol (isopropyl-13C3 99%) 1 mg/mL in methanol 1 2 mL