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Filtered Search Results
Apexbio Technology LLC Ansamitocin P-3 66547-09-9 25mg
Ansamitocin P-3 (CAS 66547-09-9) is a small-molecule inhibitor targeting tubulin It is designed to disrupt microtubule assembly by potently inhibiting tubulin polymerization thereby affecting cellular processes reliant on microtubule dynamics Ansamitocin P-3 exerts its biological activity primarily through inhibition of tubulin polymerization In cell-based studies Ansamitocin P-3 demonstrates cytotoxicity with IC50 values of approximately 4 10 g/ml in human lung carcinoma A-549 and colon carcinoma HT-29 cells and 2 10 g/ml in breast carcinoma MCF-7 cells Additionally it inhibits ciliary regeneration in Tetrahymena cells at concentrations around 1 M Based on these pharmacological properties Ansamitocin P-3 holds research potential in oncology particularly in studies of microtubule dynamics anticancer drug mechanisms and ciliogenesis
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Medchemexpress LLC 2,4,6-trimethylphenol | 527-60-6 | MFCD00002235 | 99.5% | 136.19 g/mol | C9H12O | 500 MG
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2,4,6-Trimethylphenol is an aromatic phenol used as a probe compound in research; it reacts mainly with organic matter (3DOM) and is rapidly oxidized by singlet oxygen in aqueous solution. For research use only.
- Probe compound for studies of organic matter reactivity (3DOM).
- Undergoes rapid oxidation by singlet oxygen in aqueous environments.
- High reported purity: 99.48% (data sheet) and 99.98% (documentation).
- Molecular formula C9H12O; molecular weight 136.19 g/mol.
- Solubility: DMSO 100 mg/mL (in vitro); formulatable for in vivo dosing at ≥ 2.5 mg/mL in various vehicles.
- Storage: store at 4°C under nitrogen; in solvent: -80°C (6 months) or -20°C (1 month).
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Medchemexpress LLC Apaf1 protein (human, recombinant, His-tagged) | 96.0% | 20UG
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Recombinant human Apaf1 protein (residues S104-L415) is supplied as a lyophilized, N-terminal 6xHis-tagged protein expressed in Pichia pastoris for biochemical and structural studies. The product is provided with high purity and includes buffer and storage guidance to support reliable reconstitution and downstream assays.
- Recombinant human Apaf1 covering residues S104-L415, His-tagged.
- Expressed in Pichia pastoris and supplied as lyophilized powder.
- Molecular weight approximately 37.4 kDa.
- Purity 96.0% as determined by reducing SDS-PAGE.
- Lyophilized from 20 mM Tris-HCl, 0.5 M NaCl, 6% trehalose, pH 8.0.
- Reconstitution recommended at concentrations ≥100 μg/mL for stability.
- Store lyophilized at -20°C; freeze aliquots at -20°C or -80°C for long-term storage.
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STA Pharmaceutical Fmoc-L-2,4-Dimethylphe | 5 g | CAS 1217728-65-8 | MDL MFCD06659141
Fmoc-L-2,4-Dimethylphe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1217728-65-8
- MDL: MFCD06659141
- InChIKey: MXBSNHLSKRVUBF-DEOSSOPVSA-N
- Molecular Weight: 415.489
- Molecular Formula: C26H25NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(2,4-dimethylphenyl)propanoic acid
- SMILES: CC1=CC(C)=C(C=C1)C[C@@H](C(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O
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Cambridge Isotope Laboratories 1 2 3 6 7 8-HexaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
1 2 3 6 7 8-HexaCDF (unlabeled) 25 ng/mL in nonane 0 2 mL
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Apexbio Technology LLC EZ Cap Mouse CD86 mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse CD86 mRNA encodes CD86P primarily expressed on antigen-presenting cells It binds to CD28 and CTLA-4 receptors on T cells to regulate T-cell activation and immune responses The interaction between CD86 and CD28 promotes T-cell activation and proliferation whereas its binding to CTLA-4 inhibits T-cell activity maintaining immune system balance Expression and function of CD86 are critical in various immune responses including infections tumor immunity and autoimmune diseases CD86 activity may offer novel therapeutic strategies for various immune-related disorders EZ Cap Mouse CD86 mRNA (m1 HA tag) is provided at 1 mg/mL expressing mouse-derived CD86 cytokine fused with HA tag facilitating subsequent detection It contains a cap 1 structure generated via co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
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Ambeed 6 Diphenylphosphino 2 2 bipyri
6-(Diphenylphosphino)-2,2'-bipyridine, 152194-39-3, 98%
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Ambeed 5Bromo2methoxypyridin3amine
5-Bromo-2-methoxypyridin-3-amine, 884495-39-0, 98%
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Ambeed 3 4Amino2methylpyrimidin5yl m
3-((4-Amino-2-methylpyrimidin-5-yl)methyl)-5-(2-hydroxyethyl)-4-methylthiazol-3-ium chloride, 59-43-8, 98%
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Ambeed 6Bromobenzo d isoxazol3amine
6-Bromobenzo[d]isoxazol-3-amine, 177995-39-0, 97%
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Cambridge Isotope Laboratories p-n-Nonylphenol (ring-13C6 99%) 1 mg/mL in methanol 1 2 mL
p-n-Nonylphenol (ring-13C6 99%) 1 mg/mL in methanol 1 2 mL
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Medchemexpress LLC P-Selectin Rhesus M 100ug
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P-Selectin Protein Rhesus Macaque (HEK293 His) is a member of the selectin family of cell adhesion molecules P-selectin (CD62P) has an N-terminal lectin domain an epidermal growth factor motif (generally) nine regulatory protein repeats a transmembrane section and a short intracytoplasmic tail P-selectin mediates leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells P-selectin glycoprotein ligand-1 (PSGL-1) is a major ligand for P-selectin[1][2][3] P-Selectin Protein Rhesus Macaque (HEK293 His) is the recombinant Rhesus Macaque-derived P-Selectin protein expressed by HEK293 with C-His labeled tag
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Medchemexpress LLC Tri(2-methylphenyl)phosphine | 6163-58-2 | 99.99% | C21H21P | 1 KG
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Tri(2-methylphenyl)phosphine is an organic phosphorus ligand that can be used as a drug intermediate to form complexes with metal salts. It is for research use only and not sold to patients.
- Molecular weight: 304.37
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: 4°C, protect from light, stored under nitrogen.
- In solvent: -80°C for 6 months; -20°C for 1 month (protect from light, stored under nitrogen).
- Solubility (in vitro): DMSO: 20 mg/mL (65.71 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).
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Medchemexpress LLC (-)-p-Bromotetramisole oxalate | 62284-79-1 | 99.9% | 373.22 | 25 MG
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(-)-p-Bromotetramisole oxalate (L-p-Bromotetramisole oxalate; 6-Bromolevamisole oxalate) is an alkaline phosphatase inhibitor. It is applicable for research related to erythroleukemia. It potently inhibits purified human liver, bone, spleen, and kidney alkaline phosphatase isoenzymes.
- Inhibits terminal cell division-associated MEL DS-19 cell differentiation
- Reduces B+ cell levels
- Minimally inhibits purified human intestinal and placental alkaline phosphatase isoenzymes
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Cambridge Isotope Laboratories p-n-Nonylphenol diethoxylate (ring-13C6 99%) 100 ug/mL in nonane 1 2 mL
p-n-Nonylphenol diethoxylate (ring-13C6 99%) 100 ug/mL in nonane 1 2 mL
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