Cresols
Apexbio Technology LLC EZ Cap Mouse RLI mRNA (m1Ψ) 100ug (1mg/mL)
Mouse RLI mRNA encodes a fusion protein composed of interleukin-15 (IL-15) fused to the sushi domain of its receptor IL-15R representing an innovative immunotherapeutic agent As a crucial cytokine IL-15 stimulates proliferation of natural killer (NK) cells and T cells thus enhancing immune responses against tumor cells and viruses The IL-15/IL-15R -sushi fusion protein shows promise in cancer immunotherapy by enhancing immune cell function and promoting clearance of tumor cells EZ Cap Mouse RLI mRNA (m1 )is supplied at 1 mg/mL expresses mouse-derived RLI fusion protein It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Selleck Chemical LLC Lac-Phe-E1263-25MG
N-Lactoyl-Phenylalanine (Lac-Phe) is a blood-borne signalling metabolite induced upon exercise
Medchemexpress LLC TIP 39, Tuberoinfundibular Neuropeptide | 277302-47-3 | 99.84% | 4504.20 | 1 MG
TIP 39, Tuberoinfundibular Neuropeptide is an endogenous PTH2 receptor agonist and antihypertensive agent. It selectively activates the PTH2 receptor without activity on the PTH1 receptor, stimulating cAMP production, activating adenylate cyclase, and elevating intracellular calcium levels from intracellular stores. This neuropeptide is highly conserved in humans, mice, and rats.
- Selectively activates PTH2 receptor with no activity on PTH1 receptor
- Stimulates cAMP production
- Activates adenylate cyclase
- Elevates intracellular calcium levels via mobilization from intracellular stores
- Highly conserved across humans, mice, and rats
- Applicable to research related to nociception and inflammation-induced pain
Cayman Chemical EA4 Fatty Acids and Derivative
An inhibitor of PLA2 from red blood cells (Ki = 130 µM); inhibits the ionophore-induced arachidonic acid release from human and bovine RBCs; induces mRNA expression and increases protein levels of CYP1A1 in murine hepatoma Hepa-1c1c7 cells; modulates CYP1A1 and CYP1B1 expression in MCF-7, Hep-G2, and HL-60 cells
BIOHIPPO TetOn h/m P53-sh-BSD
TetOn h/m P53-sh-BSD shRNA lentiviral vector expressing with Blasticidin selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated human P53 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human tumor suppressor protein p53 (P53/TP53) The shRNA has been validated to meet or exceed 70% P53 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Apexbio Technology LLC EZ Cap Mouse IL-12 mRNA (m1Ψ HA tag) 5x1mg (1mg/mL)
Mouse IL-12 mRNA encodes a cytokine Interleukin-12 secreted by antigen-presenting cells such as dendritic cells macrophages and B cells It promotes the activation and proliferation of T cells and natural killer (NK) cells thus enhancing the body s immune response IL-12 induces the differentiation of T cells into Th1 cells thereby enhancing cell-mediated immunity and increasing the production of interferon- (IFN- ) crucial for antiviral and antitumor immune responses EZ Cap Mouse IL-12 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-12 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins It contains a cap 1 structure generated through co-transcriptional capping Incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
TARGETMOL CHEMICALS INC EGFR-IN-9 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity. purity: 99%
Cayman Chemical Purmorphamine Other Receptor M
A 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts; binds to and activates the 7-transmembrane Smo receptor of the Hedgehog signaling pathway
STA PHARMACEUTICAL US LLC Fmoc-L-3,4-Dimethylphe | 5 g | CAS 1217620-19-3 | MDL MFCD08458428
Fmoc-L-3,4-Dimethylphe is a Amino Acid reagent (Subcategory: Phe) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1217620-19-3
- MDL: MFCD08458428
- InChIKey: QMHIEEWTOGXGNA-DEOSSOPVSA-N
- Molecular Weight: 415.489
- Molecular Formula: C26H25NO4
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(3,4-dimethylphenyl)propanoic acid
- SMILES: O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)N[C@@H](CC4=CC=C(C)C(C)=C4)C(O)=O