Cresols
BIOHIPPO h/m KRT10 shRNA Set GFP Puro
h/m KRT10 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated h/m keratin 10 (KRT10) shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse keratin 10 (KRT10) The shRNA has been validated to meet or exceed 70% KRT10 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Cayman Chemical p-chloro PhenylalnIn 25g
An inhibitor of tryptophan hydroxylase (Ki = 300 µM); a competitive inhibitor in vitro and an irreversible inhibitor in vivo; depletes serotonin to undetectable levels in rats after six days at 300 mg/kg; has commonly been used to deplete brain serotonin levels in animal studies of the serotonergic system
Apexbio Technology LLC EZ Cap Mouse IL-36γ mRNA (m1Ψ HA tag) 100ug (1mg/mL)
Mouse IL-36 mRNA encodes cytokine interleukin-36 (IL-36)Gamma primarily involved in inflammatory responses and immune regulation IL-36 acts through binding to the IL-36 receptor activating downstream signaling pathways like NF- B and MAPK promoting the release of inflammatory cytokines and activation of immune cells IL-36 is involved in multiple inflammatory disorders including psoriasis inflammatory bowel diseases and rheumatoid arthritis IL-36 may have pro-inflammatory functions in the pathological processes of these diseases making it a potential therapeutic target EZ Cap Mouse IL-36 mRNA (m1 HA tag) is supplied at 1 mg/mL It expresses mouse IL-36 cytokine fused with an HA tag facilitating subsequent detection With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo