Cresols
Apexbio Technology LLC EZ Cap Mouse IL-23 mRNA (m1Ψ HA tag) 1mg (1mg/mL)
Mouse IL-23 mRNA (Interleukin-23) encodes IL-12 cytokine It consists of two subunits IL-23 p19 and IL-12 p40 IL-23 binds to its specific receptor IL-23R activating downstream signaling pathways including the JAK-STAT pathway thus promoting inflammatory responses IL-23 is a potential therapeutic target for various diseases including psoriasis Crohn s disease and multiple sclerosis In recent years biological agents targeting IL-23 such as monoclonal antibodies have been developed for clinical application showing good efficacy and safety EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vivo
Sigma Aldrich Fine Chemicals Biosciences m-Cresol Purple sodium sal10G
m-cresol purple sodium salt (MCP) is a colorimetric pH indicator dye. The dye is blue in anionic form and yellow in protonated form.
Cayman Chemical p-chloro PhenylalnIn 25g
An inhibitor of tryptophan hydroxylase (Ki = 300 µM); a competitive inhibitor in vitro and an irreversible inhibitor in vivo; depletes serotonin to undetectable levels in rats after six days at 300 mg/kg; has commonly been used to deplete brain serotonin levels in animal studies of the serotonergic system
![Medchemexpress LLC 1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone | 1247819-59-5 | MFCD22580421 | ≥98.0% | 315.32 g·mol-1 | C12H7F2NO3S2 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000222915.png-250.jpg)
Medchemexpress LLC 1-[5-(2,4-difluorophenyl)sulfanyl-4-nitrothiophen-2-yl]ethanone | 1247819-59-5 | MFCD22580421 | ≥98.0% | 315.32 g·mol-1 | C12H7F2NO3S2 | 5 MG
A cell-permeable small-molecule inhibitor of the deubiquitinating enzyme ubiquitin-specific protease 7 (USP7) that also inhibits USP47. It is used in biochemical and cell-based studies to probe deubiquitination pathways; reported EC50 values are 8.01 μM for USP7 and 8.74 μM for USP47. Molecular formula C12H7F2NO3S2; molecular weight 315.32 g·mol-1; CAS 1247819-59-5.
- Cell-permeable small-molecule inhibitor of USP7 and USP47 (EC50 8.01 μM and 8.74 μM).
- Suitable for biochemical and cell-based deubiquitination assays.
- Reported activity values support use in target validation and pathway studies.
- Provided in small research quantities for laboratory experiments (1-10 mg).
- Molecular formula C12H7F2NO3S2 and molecular weight 315.32 g·mol-1.
eMolecules 2-Amino-4-(2,5-dimethylphenyl)thiophene-3-carbonitrile | 519016-81-0 | MFCD02244485 | 1g
Combi-Blocks | 2-Amino-4-(2,5-dimethylphenyl)thiophene-3-carbonitrile | 1g | 205395986 | QA-0906 | 95.000 | 519016-81-0 | MFCD02244485 | 228.310 | C13H12N2S
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eMolecules 2-Amino-4-(2,4-dimethylphenyl)-3-thiophenecarbonitrile | 901207-93-0 | MFCD02854968 | 1g
Combi-Blocks | 2-Amino-4-(2,4-dimethylphenyl)-3-thiophenecarbonitrile | 1g | 415497467 | QA-1161 | 98.000 | 901207-93-0 | MFCD02854968 | 228.310 | C13H12N2S
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TARGETMOL CHEMICALS INC DPH 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation. purity: 99%
Cayman Chemical 2-Methoxy-4-methylphenol 100g
A phenolic pyrolysis product of plant biomass; a volatile component of black olives and roasted coffee beans
BIOHIPPO h/m SREBP2-sh-RFP/Luc
h/m SREBP2-sh-RFP/Luc shRNA lentiviral vector expressing RFP/Luc with selection for studies in Human/Mouse Each vial provides a nominal titer of 2x10E6 transducing units TU Validated h/m SREBP2 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse sterol regulatory element binding transcription factor 2 (SREBP2/SREBF2) The shRNA has been validated to meet or exceed 70% knockdown of SREBP2 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs