Cresols
Medchemexpress LLC 3-(2-Pyridyldithio)propanoic acid | 68617-64-1 | 99.5% | 1 G
3-(2-Pyridyldithio)propanoic acid is an alkyl chain-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are molecules that contain two different ligands connected by a linker, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- For research use only
Medchemexpress LLC NPR2 Human P. past 2ug
NPR2 Protein Human (P pastoris His) serves as the receptor for C-type natriuretic peptide NPPC/CNP activating guanylate cyclase upon ligand binding NPR2 potentially regulates skeletal growth indicating involvement in bone development Its interaction with C-type natriuretic peptide highlights its significance in mediating cellular responses especially in signaling pathways influencing skeletal growth dynamics NPR2 Protein Human (P pastoris His) is the recombinant human-derived Atrial natriuretic peptide receptor 2/NPR2 expressed by P pastoris with N-His labeled tag
Medchemexpress LLC NY-ESO-1 (157-165) peptide TFA | 97.6% | 1208.37 | 10 MG
NY-ESO-1 (157-165) peptide (TFA) is a peptide fragment from the NY-ESO-1 protein. It can activate the immune system, particularly in HLA-A2 positive individuals, by being recognized by CD8+ T cells, thereby triggering an immune response. This peptide is expressed in various tumors and can be utilized as a target for tumor immunotherapy.
- Peptide fragment from NY-ESO-1 protein
- Activates the immune system in HLA-A2 positive individuals
- Recognized by CD8+ T cells, triggering an immune response
- Expressed in various tumors
- Can be used as a target for tumor immunotherapy
- Highly immunogenic epitope of NY-ESO-1
- Can induce spontaneous or vaccine-induced T cell immune responses
Medchemexpress LLC P 22077 | 1247819-59-5 | 98.4% | 315.32 | 50 MG
P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with an EC50 of 8.01 μM. It also inhibits USP47 with an EC50 of 8.74 μM.
- USP7 inhibitor (EC50: 8.01 μM)
- USP47 inhibitor (EC50: 8.74 μM)
- Cell-permeable
- Inhibits a smaller subset of DUBs at 15-45 μM
- Causes DUBs inhibition in HEK293T cells at 25 μM
- Greatly reduces cell viability of neuroblastoma (NB) cells
- Increases p53 activity and induces apoptosis in p53 wild-type and HDM2-expressing NB cells at 10 μM
- Enhances cytotoxic effect of Dox and VP-16 on NB cells, and enhances Dox- and VP-16-induced p53-mediated apoptosis at 5 μM
- Shows potent antitumor activities in xenograft mouse models bearing IMR-32-derived tumors
- Exhibits antitumor effects in mice bearing SH-SY5Y-derived tumors and NGP-derived tumors
Medchemexpress LLC Ny-eso-1 (157-165) peptide Tfa | >97.6% | 1208.37 | 5 MG
NY-ESO-1 (157-165) peptide (TFA) is a peptide fragment derived from the NY-ESO-1 protein. It is capable of activating the immune system, particularly in HLA-A2 positive individuals, by being recognized by CD8+ T cells to initiate an immune response. This peptide is expressed in various tumors and is considered a potential target for tumor immunotherapy.
- Highly immunogenic epitope of NY-ESO-1
- Capable of inducing spontaneous or vaccine-induced T cell immune responses
- Expressed in various tumors, making it a target for immunotherapy
Medchemexpress LLC p-Hydroxymandelic acid | 1198-84-1 | 98.9% | 168.15 | 250 MG
p-Hydroxymandelic acid is a valuable aromatic fine chemical used widely for the production of pharmaceuticals and food additives. It is also utilized for the preparation of 4-hydroxyphenylacetic acid, which is a synthetic precursor for the selective β1-receptor antagonist drug atenolol. This compound can conjugate cytotoxic drugs and enzyme substrates, suggesting its application in targeted drug delivery systems.
- Valuable aromatic fine chemical.
- Widely used in pharmaceuticals and food additives.
- Precursor for 4-hydroxyphenylacetic acid, which is used to synthesize atenolol.
- Can be used in targeted drug delivery systems by conjugating cytotoxic drugs and enzyme substrates.
- For research use only.
Medchemexpress LLC Atrial natriuretic peptide (3-28) (human) | 102686-43-1 | 99.7% | 2880.21 | 1 MG
Atrial natriuretic peptide (3-28) (human) is a peptide hormone synthesized and secreted by the atrial myocardium. It plays a role in the regulation of blood pressure, fluid balance, and electrolyte homeostasis.
- Regulates blood pressure
- Affects fluid balance
- Influences electrolyte homeostasis
Medchemexpress LLC Moracin P | 102841-46-3 | 5 MG
Moracin P is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. It exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1) and reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin P has neuroprotective and anti-inflammatory effects, and enhances cell viability against OGD-induced cell death in neuroblastoma SH-SY5Y cells.
- Potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1)
- Reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production
- Possesses neuroprotective effects
- Possesses anti-inflammatory effects
- Enhances cell viability against oxygen-glucose deprivation (OGD)-induced cell death
TARGETMOL CHEMICALS INC 740 Y-P 5MG
Also available in 1 mg 10 mg 25 mg 50 mg and bulk. Please contact Fisher for quotes. 740 Y-P (740YPDGFR) is a potent and cell-permeable activator of PI3K. purity: 99%
eMolecules 6627-55-0 | 2-Bromo-4-methylphenol | Combi-Blocks | MFCD00002151 | 187.036 | C7H7BrO | 98.000 | Cc1ccc(O)c(Br)c1 | 100g | 232308089
2-Bromo-4-methylphenol | Combi-Blocks | 6627-55-0 | MFCD00002151 | 187.036 | C7H7BrO | 98.000 | Cc1ccc(O)c(Br)c1 | 100g | 232308089
Medchemexpress LLC N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide | 134865-74-0 | MFCD00901545 | >99.0% | 279.38 g/mol | C19H21NO | 50 MG
4-P-PDOT is a potent, selective melatonin MT2 receptor antagonist used as an analytical standard and research reagent. It exhibits >300-fold selectivity for MT2 over MT1 and is supplied in small quantities suitable for biochemical and pharmacological studies; consult the Certificate of Analysis for purity and storage.
- Potent and selective MT2 antagonist.
- High receptor selectivity (>300-fold) for MT2 versus MT1.
- Intended for use as an analytical standard and research reagent.
- Available in small packaging sizes, including 50 mg.
- Molecular formula C19H21NO and molecular weight 279.38 g/mol.
- CAS number 134865-74-0 for unambiguous identification.
Medchemexpress LLC phospho-PI3 Kinase p110 beta (Ser1070) Antibody | 10 UL
This antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, specifically targeting phospho-PI3 Kinase p110 beta (Ser1070).
- Host: Rabbit
- Clonality: Polyclonal
- Species reactivity: Human, mouse, rat
- Application: WB (1:500-2000), IHC-P (1:100-500), IHC-F (1:100-500), ICC/IF (1:100-500)
- Purity: Affinity purified
- Modification: Phosphorylated
- Isotype: IgG
- Appearance: Liquid
- Formulation: Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Storage: Stored at -20°C for 1 year
- Avoid repeated freeze / thaw cycles
eMolecules 123-11-5 | p-Anisaldehyde | Chem-Impex | MFCD00003385 | 136.150 | C8H8O2 | 99.000 | COc1ccc(C=O)cc1 | 5kg | 510432154
p-Anisaldehyde | Chem-Impex | 123-11-5 | MFCD00003385 | 136.150 | C8H8O2 | 99.000 | COc1ccc(C=O)cc1 | 5kg | 510432154
Medchemexpress LLC N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide | 134865-74-0 | MFCD00901545 | >99.0% | 279.38 g/mol | C19H21NO | 100 MG
4-P-PDOT is an analytical standard of a selective melatonin MT2 receptor antagonist used as a reference compound in pharmacology and analytical research. It is supplied as a high-purity solid for characterization, assay development, and receptor pharmacology studies.
- Analytical standard for research and assay calibration.
- Selective MT2 melatonin receptor antagonist.
- High purity (>99.0%).
- Molecular formula C19H21NO.
- Molecular weight 279.38 g/mol.
- Provided as a 100 MG solid.
- CAS number 134865-74-0.