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Filtered Search Results
Medchemexpress LLC OT-82 | 1800487-55-1 | 99.95% | 424.47 | 10 MG
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OT-82 is a potent, selective, and orally active inhibitor of NAMPT. It is selectively toxic to cells of hematopoietic origin and induces cell death in a NAD+ dependent manner. It is a promising antineoplastic agent for the study of hematological malignancies.
- Potent, selective, and orally active NAMPT inhibitor
- Selectively toxic to cells of hematopoietic origin
- Induces cell death in a NAD+ dependent manner
- Promising antineoplastic agent
- Demonstrates tissue-selective cytotoxicity
- Inhibits recombinant NAMPT activity
- Reduces cellular NAD and ATP concentrations
- Activates caspase-3 and increases sub-G1 DNA content
- Depolarizes the mitochondrial membrane
- Increases survival in a SC xenograft model of Burkitt's lymphoma
- Potently inhibits tumor growth in a multiple myeloma mouse model
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Medchemexpress LLC Maltodextrin | 9050-36-6 | MFCD00146679 | Variable (no fixed molecular weight; polymeric - represented as (C6H10O5)n·xH2O) | (C6H10O5)n·xH2O | 100 G
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Maltodextrin, dextrose equivalent 16.5-19.5 is a water-soluble polysaccharide used as an excipient and formulation aid in research applications. It provides intermediate hydrolysis (DE 16.5-19.5) and is supplied as a white to off-white powder for laboratory use.
- Water-soluble excipient for stabilization and encapsulation.
- Intermediate dextrose equivalent for balanced solubility and viscosity.
- Forms nanoparticles with narrow size distribution for delivery studies.
- Non-toxic at tested concentrations in cell assays.
- Available in common laboratory pack sizes for research use.
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Apexbio Technology LLC Regorafenib hydrochloride(Synonyms: Regorafenib HCl, BAY 73-4506, Stivarga, BAY73-4506 hydrochloride, Regorafenib hydrochloride salt), 10mM (in 1mL DMSO), CAS: 835621-07-3.
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Regorafenib hydrochloride (CAS 835621-07-3) is an orally bioavailable small molecule inhibitor targeting multiple protein kinases including c-KIT VEGFR2 and B-Raf It inhibits these kinases with IC50 values of approximately 17 nM (c-KIT) 40 nM (VEGFR2) and 69 nM (B-Raf) By blocking kinase signaling Regorafenib hydrochloride effectively interrupts tumor-associated pathways involved in cell proliferation angiogenesis and survival It is widely used in oncology research for studies focused on kinase-mediated tumor growth and vascularization mechanisms
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Medchemexpress LLC (S)-4-amino-3-hydroxybutanoic acid | 7013-05-0 | MFCD00672884 | 95.0% | 119.12 g·mol⁻1 | C4H9NO3 | 25 G
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S-(+)-GABOB (S-4-amino-3-hydroxybutanoic acid) is the S-enantiomer of GABOB, an endogenous GABA metabolite with reported antiepileptic activity. Supplied as a research-grade reagent with 95.0% purity, it is intended for laboratory research use only.
- 95.0% purity
- Molecular weight 119.12 g·mol⁻1
- Chemical formula C4H9NO3
- SMILES: O=C(C[C@@H](CN)O)O
- Available as a 25 G pack for laboratory use
- For research use only; not for human or clinical applications
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Medchemexpress LLC 3,6-dichloropyridine-2-carboxylic acid | 1702-17-6 | MFCD00078655 | 98.5% | 192.00 g/mol | C6H3Cl2NO2 | 25 G
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Clopyralid (3,6-dichloropyridine-2-carboxylic acid) is a selective pyridine herbicide supplied as a research-grade reagent for analytical, formulation, and experimental use. Supplied as a high-purity solid (CAS 1702-17-6), it is used in studies of herbicidal activity, environmental fate, and formulation development; consult the certificate of analysis and safety data sheet for handling and storage.
- High purity (98.52%), suitable for analytical applications.
- Confirmed identity as 3,6-dichloropyridine-2-carboxylic acid (CAS 1702-17-6).
- Available in multiple pack sizes, including 25 g.
- Appropriate for herbicide activity, toxicology, and environmental fate studies.
- Certificate of analysis and safety data sheet available for batch-specific information.
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![Alkali Scientific Luria Broth [Miller's LB] 1 Liter Buffered Capsules, 200 Capsules of 25 Grams, 5 Kg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660615.jpg-250.jpg)
Alkali Scientific Luria Broth [Miller's LB] 1 Liter Buffered Capsules, 200 Capsules of 25 Grams, 5 Kg
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Luria Broth [Miller's LB] 1 Liter Buffered Capsules, 200 Capsules of 25 Grams, 5 Kg is a large-volume culture medium designed for high-throughput laboratories or those requiring a large supply of growth media. The buffered formula ensures pH stability throughout the incubation process, which is crucial for maintaining optimal growth conditions for microorganisms. The 5 Kg size is ideal for labs that frequently perform large-scale culturing, bacterial transformation, or protein expression. This medium is commonly used in molecular biology applications for growing E. coli and other bacterial strains. The capsules are easily dissolved in water, making media preparation fast and convenient.
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Sigma Organic Chemistry Trifluoroethylene | 25G | 359-11-5 | MFCD00039275
Trifluoroethylene , 25G
About this item:
CAS #: 359-11-5
MDL #: MFCD00039275
Purity: 97 5%
Molecular Weight: 82.02
UNSPSC Code: 12352100
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Medchemexpress LLC Decamethylcyclopentasiloxane | 541-02-6 | 99.6% | 370.77 | 250 G
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Decamethylcyclopentasiloxane (D5) is an organosilicon compound utilized as a skin emollient in cosmetics and personal care products. For research use only. We do not sell to patients.
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Medchemexpress LLC Oxalyldihydrazide | 996-98-5 | 98.0% | 118.09 | 100 G
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Oxalyldihydrazide is a crosslinking agent used in proteomics research. It can capture carbonylated proteins on the surface of a microchip. It is for research use only and not sold to patients.
- Crosslinking agent in proteomics research.
- Can capture carbonylated proteins on the surface of a microchip.
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Medchemexpress LLC Ethylenediaminetetraacetic acid | 60-00-4 | MFCD00003541 | ≥98.0% | 292.24 g/mol | C10H16N2O8 | 100g
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Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations including calcium) Ethylenediaminetetraacetic acid has antibacterial anti-inflammatory antioxidant anti-hypercalcemia and anticoagulant activities Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins and allows maintenance of reducing environment during protein purification Ethylenediaminetetraacetic acid can alleviate the liver fibrosis Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7]
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Medchemexpress LLC Cathepsin Z (CTSZ) recombinant protein, mouse | >95.0% | 50 UG
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Recombinant mouse Cathepsin Z (CTSZ) is a C-terminal His-tagged protein expressed in HEK293 cells, supplied as a lyophilized powder formulated in PBS, pH 7.4. It displays enzymatic activity suitable for biochemical assays and is provided at high purity for research applications.
- Expressed in HEK293 cells with C-terminal His tag.
- Supplied as lyophilized powder for stable storage and handling.
- Purity greater than 95% as determined by reducing SDS-PAGE.
- Specific activity 715.46 pmol/min/μg for enzymatic assays.
- Formulated in PBS, pH 7.4; recommend aliquoting and freezing for long-term storage.
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Medchemexpress LLC Pantoprazole impurity 42 | 107512-34-5 | 157.60 | C7H8ClNO | 25 G
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Pantoprazole impurity 42 is a defined impurity and analytical reference standard related to the proton-pump inhibitor pantoprazole. It is intended for research and analytical use, including method development and impurity profiling.
- Defined impurity for analytical characterization.
- Suitable as a reference standard or drug intermediate.
- CAS number 107512-34-5; molecular formula C7H8ClNO.
- Molecular weight 157.60 g/mol.
- Intended for research use only; not for human or clinical use.
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Medchemexpress LLC NVP-BSK805 dihydrochloride | 1942919-79-0 | 99.0% | 563.47 | 25 MG
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NVP-BSK805 dihydrochloride is an ATP-competitive inhibitor primarily targeting JAK2, with high selectivity over other JAK family members like JAK1, JAK3, and TYK2. It effectively suppresses the growth of JAK2V617F-bearing acute myeloid leukemia cell lines and blocks STAT5 phosphorylation. This compound also enhances the sensitivity of drug-resistant cancer cells to certain treatments by improving P-gp inhibitory activity.
- Potent ATP-competitive JAK2 inhibitor
- Selective inhibition over JAK1, JAK3, and TYK2
- Suppresses JAK2V617F-bearing acute myeloid leukemia cell growth
- Blocks STAT5 phosphorylation
- Improves P-gp inhibitory activity
- Increases sensitization of drug-resistant cancer cells to treatments
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Apexbio Technology LLC HyperTrap Q FF Column 5ml
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The HyperTrap Q FF Column is not a small molecule but a chromatography medium designed for the purification of biomolecules particularly proteins and nucleic acids It operates via strong anion exchange chromatography utilizing quaternary ammonium functional groups immobilized on a Fast Flow resin matrix to selectively bind negatively charged molecules under defined buffer conditions This allows for efficient separation and recovery of target biomolecules from complex mixtures The HyperTrap Q FF Column is applied in research settings for desalting buffer exchange and isolation of nucleic acids or proteins supporting downstream analyses and preparative workflows in the biomedical field
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Medchemexpress LLC N-Phenylbenzamide 25g
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N-Phenylbenzamide (N-Benzoylaniline) is a compound skeleton N-Phenylbenzamide can be used for the researches of cancer and infection such as enterovirus and cervical cancer[1][2]
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