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Filtered Search Results
Medchemexpress LLC Phenol, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis- | 51094-17-8 | MFCD00191501 | 98.0% | 678.73 | C44H30N4O4 | 1 G
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5,10,15,20-Tetrakis(4-hydroxyphenyl)porphyrin is a porphyrin-based organic reagent used in life-science research, photophysical studies, and materials science. Provided as a solid (brown to black) with high reported purity, it is applied in photodynamic experiments, sensor development, and porphyrin chemistry research.
- High purity suitable for analytical and research applications.
- Solid form simplifies storage and handling.
- Useful in photodynamic and photophysical experiments.
- Applicable in sensor and materials research.
- Stable when stored protected from light under recommended conditions.
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Medchemexpress LLC Pivaloyloxymethyl chloride | 18997-19-8 | MFCD00000884 | 100.0% | 150.60 g/mol | C6H11ClO2 | 100g
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Pivaloyloxymethyl chloride is an intermediate Pivaloyloxymethyl chloride can be used in the synthesis of Compound 8b Compound 8b can stimulate the production of interferon gamma[1]
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Apexbio Technology LLC Rolapitant HCl 552292-08-7 (free base) 1mg
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Rolapitant HCl is a small-molecule antagonist targeting the neurokinin NK1 receptor It is designed to block NK1 receptor signaling pathways thereby reducing receptor activation mediated by substance P Rolapitant HCl exerts its biological activity primarily through competitive antagonism of the NK1 receptor In preclinical models including gerbils and ferrets rolapitant suppressed both acute and delayed emetic responses induced by NK1 receptor agonists Based on these pharmacological properties rolapitant HCl holds research potential in the management of postoperative nausea and vomiting
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Apexbio Technology LLC Ginsenoside F2 62025-49-4 20mg
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Ginsenoside F2 (CAS 62025-49-4) is a saponin compound isolated from Panax ginseng C A Mey It has been studied for its modulatory effects on cellular signaling pathways involved in cell proliferation apoptosis and metabolic regulation Ginsenoside F2 is reported to influence key mediators such as caspases and the PI3K/Akt pathway contributing to its investigation in cancer biology and neuroprotection The compound is soluble in water methanol and ethanol supporting its use in a variety of in vitro and in vivo research settings Its stability is maintained under sealed cool and dry storage conditions
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Apexbio Technology LLC ZM 39923 HCl 1021868-92-7 10mM (in 1mL DMSO)
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ZM 39923 HCl (CAS 1021868-92-7) is a small molecule that selectively inhibits Janus kinases JAK1 and JAK3 displaying pIC50 values of 4 4 and 7 1 respectively As JAK family kinases play a pivotal role in cytokine-mediated signaling via the JAK-STAT pathway ZM 39923 HCl is frequently employed to investigate signal transduction mechanisms linked to hematological malignancies autoimmune conditions and inflammatory disorders The compound also inhibits tissue transglutaminase 2 (TGM2) with an IC50 of 10 nM and exhibits equivalent inhibition of EGFR In cellular studies ZM 39923 HCl modulates T cell proliferation and apoptosis and affects pathways involving VEGF and TGF 2 underscoring its utility in cytokine oncology and cell biology research
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Medchemexpress LLC Chloropretadalafil 25g
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Chloropretadalafil (Compound 31) is a key intermediate that can be used to synthesize Tadalafil (HY-90009A) derivatives[1]
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Medchemexpress LLC 2,3,4,6-tetra-O-pivaloyl-α-D-glucopyranosyl bromide | 81058-27-7 | MFCD08275217 | 100g
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Empagliflozin impurity 15 is an impurity of Empagliflozin (HY-15409)
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eMolecules 131747-43-8 | 2-Trifluoromethylnicotinic acid | Ambeed | MFCD01862052 | 191.109 | C7H4F3NO2 | 98.000 | OC(=O)c1cccnc1C(F)(F)F | 100g | 552709069
2-Trifluoromethylnicotinic acid | Ambeed | 131747-43-8 | MFCD01862052 | 191.109 | C7H4F3NO2 | 98.000 | OC(=O)c1cccnc1C(F)(F)F | 100g | 552709069
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Medchemexpress LLC L-selectin/CD62L protein, mouse (HEK293, His) | ≥98.0% | 50 UG
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Recombinant mouse L-selectin (CD62L) is the extracellular domain of the protein expressed in HEK293 cells with a C-terminal His tag. It is supplied as a 0.22 μm filtered PBS solution (pH 7.4) at 0.34 mg/mL, with an approximate molecular weight of 70-80 kDa and high purity suitable for research applications in immunology and cell adhesion studies.
- Recombinant mouse extracellular domain suitable for in vitro assays.
- Expressed in HEK293 for mammalian-like post-translational modifications.
- C-terminal His tag facilitates purification and detection.
- Supplied as a filtered PBS solution ready for dilution or use.
- High purity (≥98.0%) supports biochemical and binding studies.
- Concentration provided for convenient aliquoting and dosing.
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Medchemexpress LLC Ethanol, 2,2'-[iminobis(2,1-ethanediyloxy)]bis- | 54384-47-3 | MFCD00239212 | 97.0% | 193.24 g/mol | C8H19NO4 | 1 G
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NH-bis-PEG2 is a short, non-cleavable two-unit polyethylene glycol (PEG) linker used as a hydrophilic spacer in conjugation chemistry. It is commonly employed in the synthesis of antibody-drug conjugates (ADCs) and proteolysis targeting chimeras (PROTACs) for research applications.
- Non-cleavable two-unit PEG linker
- Used for ADC and PROTAC synthesis
- High purity: 97.0% (NMR)
- Molecular weight 193.24 g/mol and formula C8H19NO4
- Available as a 1 G package
- Store protected from light at 4°C; in solvent, -80°C (up to 6 months) or -20°C (up to 1 month)
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Medchemexpress LLC Cucurbitacin E | 18444-66-1 | 556.69 | 1 ML
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Cucurbitacin E is a natural compound derived from Cucurbitaceae plants. It significantly suppresses the activity of the cyclin B1/CDC2 complex and exhibits antitumor activity.
- Natural compound
- Suppresses cyclin B1/CDC2 complex activity
- Used in cancer research
- Explored for antitumor activity against colorectal cancer cells
- Induces morphological changes in primary colon cancer cells
- Inhibits tumor growth by arresting the cell cycle
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Medchemexpress LLC 6-bromo-3-fluoropyridine-2-carbaldehyde | 885267-36-7 | MFCD07781224 | 99.9% | 204.00 g/mol | C6H3BrFNO | 25 G
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6-Bromo-3-fluoropyridine-2-carbaldehyde is an organic intermediate used in medicinal chemistry and small-molecule synthesis. It features a brominated and fluorinated pyridine ring with an aldehyde functionality, enabling a range of derivatization and coupling reactions. CAS 885267-36-7; molecular formula C6H3BrFNO; molecular weight 204.00 g/mol.
- Used as an intermediate in medicinal chemistry and small-molecule synthesis.
- White to light yellow solid appearance.
- High purity: 99.9% (GC).
- Molecular formula C6H3BrFNO; molecular weight 204.00 g/mol.
- Suitable for aldehyde-based derivatization and coupling reactions.
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Medchemexpress LLC Griseofulvin | 126-07-8 | 98.9% | 352.77 | 25 G
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Griseofulvin is an orally active antifungal antibiotic that also exhibits antitumor activity. It induces apoptosis and G2/M cell cycle arrest in cancer cells. Additionally, Griseofulvin has cardiovascular modulatory effects, including reducing angina pectoris, alleviating hand artery spasm associated with onychomycosis, and treating peripheral vascular diseases like shoulder-hand syndrome.
- Orally active antifungal antibiotic
- Exhibits antitumor activity
- Induces apoptosis and G2/M cell cycle arrest in cancer cells
- Cardiovascular modulatory effects
- Reduces angina pectoris
- Alleviates hand artery spasm associated with onychomycosis
- Treats peripheral vascular diseases like shoulder-hand syndrome
- For research use only
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Medchemexpress LLC INCB059872 dihydrochloride | 3062683-32-0 | 97.9% | C23H34N2O3 • 2HCl | 50 MG
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INCB059872 dihydrochloride is a potent, selective, and irreversible inhibitor of Lysine-Specific Demethylase 1 (LSD1). It exhibits potential antineoplastic activity and can be used in acute myeloid leukemia (AML) research. It has been shown to decrease proliferation in THP-1 acute monocytic and MV4-11 acute myeloid leukemia cells, and to increase the levels of CD11B in THP-1 cells when used at a concentration of 100 nM.
- Potent, selective, and irreversible LSD1 inhibitor
- Potential antineoplastic activity
- Useful in acute myeloid leukemia (AML) research
- Decreases proliferation in acute monocytic and myeloid leukemia cells
- Increases levels of CD11B in THP-1 cells
- Cited in Nature Medicine
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Medchemexpress LLC 2-BROMO-2 -METHOXYAC 10G | 10G
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2-BROMO-2 -METHOXYAC 10G | 10G
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