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Filtered Search Results
Medchemexpress LLC Desipramine hydrochloride | 58-28-6 | 99.8% | 500 MG
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Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT) with Ki values of 4, 61, and 78,720 nM, respectively. It is intended for research use only.
- Inhibits norepinephrine transporter (NET), 5-HT transporter (SERT), and dopamine transporter (DAT).
- High purity of 99.76%.
- Available in various quantities and formulations (solid, solution in DMSO).
- Used in numerous publications, including studies on cell proliferation/viability, apoptosis-related proteins, and various cellular staining methods.
- Relevant in research areas such as infection, neurological diseases, and cancer.
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Medchemexpress LLC Cefazolin sodium | 27164-46-1 | 98.5% | 10 MM 1 ML
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Cefazolin sodium is a first-generation cephalosporin antibiotic used in bacterial infections research. It has anti-inflammatory effects and can attenuate post-operative cognitive dysfunction (POCD). It demonstrates various biological activities including:
- Direct anti-inflammatory effect on C8-B4 cells
- Inhibition of IL-2, IL-4, and IL-15-induced cell proliferation
- Improvement of learning and memory in mice after surgery
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Medchemexpress LLC Methanediol, 1-(5-nitro-2-furanyl)-, 1,1-diacetate | 92-55-7 | MFCD00003244 | >98.0% | 500g
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IITR01324 is an antimicrobial agent IITR01324 has antimicrobial activity against Escherichia coli (MIC 3 58 mg/L) and other Gram-negative bacteria (Shigella flexneri MIC 3 58 mg/L Cronobacter sakazakii MIC 28 63 mg/L) IITR01324 exerts its antimicrobial activity by destroying bacterial DNA after activation of intracellular reductases IITR01324 can be used to study the development of new antimicrobial drugs especially against multidrug-resistant (MDR) pathogens[1]
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Medchemexpress LLC Quinacrine (dihydrochloride) | 69-05-6 | 99.4% | 472.88 | 1 G
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Quinacrine dihydrochloride, also known as Mepacrine dihydrochloride, is an orally bioavailable antimalarial agent with demonstrated anticancer effects both in vitro and in vivo. It functions by suppressing NF-kB and activating p53 signaling pathways, which ultimately leads to the induction of apoptosis.
- Targets autophagy, mitophagy, parasite, and apoptosis
- Involved in autophagy, anti-infection, and apoptosis pathways
- Inhibits the growth of SGC-7901 cells
- Induces apoptosis in SGC-7901 cells via mitochondria-dependent signaling
- Increases levels of proapoptotic proteins (cytochrome c, Bax, p53)
- Decreases antiapoptotic protein Bcl-2
- Significantly suppresses circulating blast cells in an AML-PS model
- Increases median survival time in AML mouse models
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Medchemexpress LLC MSX-122 | 897657-95-3 | 98.2% | 292.34 | 1 ML
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MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions with an IC50 of approximately 10 nM. This compound demonstrates anti-inflammatory and anti-metastatic activity. It is intended for research use only.
- Orally active partial antagonist of CXCR4
- Inhibits CXCR4/CXCL12 actions
- Exhibits anti-inflammatory activity
- Exhibits anti-metastatic activity
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Medchemexpress LLC Chloroxylenol | 88-04-0 | 99.5% | 100 G
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Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi, and viruses. It inhibits the viability, proliferation, migration, invasion, and sphere formation, and induces apoptosis in HCT116 and SW480 cells by inhibiting the Wnt/β-catenin signaling pathway. It also inhibits nuclear translocation of β-catenin in HCT116 and SW480 cells and inhibits the growth of CRC organoids. In vivo, Chloroxylenol inhibits tumor growth in a MC38 cell xenograft model.
- Broad-spectrum antibacterial agent
- Effective against bacteria, algae, fungi, and viruses
- Inhibits Wnt/β-catenin signaling pathway
- Induces apoptosis in certain cancer cells
- Inhibits tumor growth in xenograft models
- Potential for anti-cancer activity in colorectal cancer
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Chemscene CHEMSCENE
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5000578552 HEXADECYLTRIMETHYLAMMONIU 250G
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Chemscene CHEMSCENE
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5000578028 RHODANINE 500G
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Chemscene CHEMSCENE
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5000578079 BENZYLTRIPHENYLPHOSPHONIU 100G
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Chemscene CHEMSCENE
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5000578072 ALLYLTRIPHENYLPHOSPHONIUM 100G
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Medchemexpress LLC PR-104A | 680199-06-8 | 99.0% | C14H19BrN4O9S | 1 ML
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PR-104A (SN 27858) is the alcohol metabolite of the phosphate proagent PR-104. It functions as a hypoxia-selective DNA cross-linking and damaging agent and cytotoxin with antitumor activity. It undergoes metabolism under hypoxic conditions via the 1-electron NADPH:cytochrome P450 oxidoreductase and is utilized in research concerning relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL).
- Functions as a hypoxia-selective DNA cross-linking agent
- Acts as a DNA-damaging agent and cytotoxin
- Exhibits antitumor activity
- Undergoes metabolism under hypoxic conditions via 1-electron NADPH:cytochrome P450 oxidoreductase
- Utilized in research concerning relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL)
- For research use only
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Medchemexpress LLC Methenamine hippurate | 5714-73-8 | MFCD00072147 | >95.0% | 319.36 g/mol | C15H21N5O3 | 10 MG
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Methenamine hippurate is the analytical reference standard of methenamine hippurate supplied for research and analytical use. The compound is the hippurate salt of methenamine, an orally active urinary antiseptic that releases formaldehyde under acidic conditions; supplied as a dry solid and handled per SDS storage recommendations.
- Analytical reference standard suitable for research and quality control.
- CAS number 5714-73-8; molecular weight 319.36 g/mol.
- Purity reported by suppliers as ≥95% (HPLC) to ≥98%; check lot-specific certificate.
- Recommended storage: 4°C sealed and dry; in solution -80°C (6 months) or -20°C (1 month).
- Provided as a solid for analytical preparation and formulation testing.
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Medchemexpress LLC Bupivacaine hydrochloride | 18010-40-7 | MFCD00078956 | 100.0% | 324.89 | C18H29ClN2O | 10 MG
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Bupivacaine hydrochloride is an analytical reference standard of the local anesthetic bupivacaine supplied for research and analytical applications. It is intended for use in chromatographic assays, method development, and studies of sodium-channel and NMDA-receptor pharmacology.
- Analytical reference standard for chromatography and assay.
- High purity: 99.99% (as stated by manufacturer).
- CAS number: 18010-40-7.
- Molecular formula: C18H29ClN2O.
- Molecular weight: 324.89.
- Packaged in a brown glass bottle and supplied in small-mass quantities suitable for analytical use.
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Medchemexpress LLC TPABR 98 100G
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5000206043 TPABR 98 100G
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Takara Bio Takara IVTpro mRNA Synthesis System (BspQ )
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Takara IVTpro mRNA Synthesis S
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