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Filtered Search Results
eMolecules DEPBT 100G
5000163123 DEPBT 100G
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eMolecules 3-BENZYLOXYCYCLOBUTANONE 10G
5000225967 3-BENZYLOXYCYCLOBUTANONE 10G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000657047 TIRON 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000381005 FERRIOXAMINE E 1MG
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Medchemexpress LLC Tk-112690 | 22423-26-3 | 240.21 | 100 G
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TK-112690 is an inhibitor of UPP1 (uridine phosphorylase 1). It effectively inhibits murine small intestinal uridine phosphorylase (UPase) with an IC50 of 12.5 μM and human small intestinal UPase with an IC50 of 20.0 μM in laboratory settings. The compound has been observed to increase plasma uridine concentration in mice and is utilized for research purposes related to cancer and pulmonary fibrosis.
- Functions as a UPP1 inhibitor.
- Demonstrates in vitro inhibition of murine small intestinal uridine phosphorylase (UPase) with an IC50 of 12.5 μM.
- Exhibits in vitro inhibition of human small intestinal UPase with an IC50 of 20.0 μM.
- Increases plasma uridine concentration in mice.
- Applicable for the study of cancer and pulmonary fibrosis.
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Medchemexpress LLC Skatole | 83-34-1 | 131.17 | 25 G
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Skatole (3-methylindole) is a heterocyclic compound found naturally in the feces of vertebrates and certain plants. It is produced by intestinal bacteria and can induce apoptosis of intestinal epithelial cells by activating aryl hydrocarbon receptors (AhR) and p38. Skatole is also used in the perfume industry and as a flavor additive in ice cream.
- Human endogenous metabolite
- P38 target
- Microbial metabolite
- Aryl hydrocarbon receptor target
- Leads to intestinal epithelial cell apoptosis in a time and dose dependent manner
- Activates AhR and p38
- Reverses the suppression of Irisin on Ang II-evoked proliferation, migration, and phenotypic transformation in VSMCs
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eMolecules DIHYDROURACIL 25G
5000160994 DIHYDROURACIL 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369770 ELLIPTICINE HYDROCH 100MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369795 LB AGAR 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000369800 NUTRIENT AGAR 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000596549 SODIUM ACETYLATED HY 500MG
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Medchemexpress LLC Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) | FZD7 receptors antagonist | 2247635-23-8 | 99.6% | 1796.05 | 1 MG
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Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors. It selectively binds to the FZD7 CRD subclass, altering the conformation of the CRD and the architecture of its lipid-binding groove. This compound impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids.
- Potent peptide antagonist of FZD7 receptors
- Selectively binds to FZD7 CRD subclass
- Alters CRD conformation and lipid-binding groove architecture
- EC50 values: 58 nM (human FZD7 CRD) and 34 nM (mouse FZD7 CRD)
- Impairs Wnt signaling with an IC50 value of 100 nM in HEK293-TB cells
- Blocks WNT3A-mediated stabilization of β-catenin in mouse L cells with an IC50 value of 50 nM
- Disrupts LGR5+ stem cell function in LGR5-GFP+ stem cells at 200 μM over 48 hours
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Medchemexpress LLC Diphenylmethanimine | 1013-88-3 | 181.23 | 100 G
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Diphenylmethanimine is a biochemical reagent used in life science research as a biological material or organic compound.
- It is useful in the preparation of nitrogen ylide dimers.
- It functions as an ammonia surrogate in certain reactions.
- It serves as an intermediate material for the synthesis of various organic chemicals.
- It can be used in catalytic enantioselective alkylation of the benzophenone imine of glycine t-butyl ester, yielding amino acid derivatives with excellent yields when using phosphazene (Schwesinger) bases and chiral quaternary ammonium salts.
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Alkali Scientific ALKALI SCIENTIFIC INC
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5000661911 BROMOPHENOL BLUE TRACKING DYE
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Alkali Scientific ALKALI SCIENTIFIC INC
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5000661912 R2B BROTH/ 500G
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