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Filtered Search Results
eMolecules 126-38-5 | 1-Bromo-2,2-dimethoxypropane | Ambeed | MFCD00000208 | 183.045 | C5H11BrO2 | 97.000 | COC(C)(CBr)OC | 5g | 525235803
1-Bromo-2,2-dimethoxypropane | Ambeed | 126-38-5 | MFCD00000208 | 183.045 | C5H11BrO2 | 97.000 | COC(C)(CBr)OC | 5g | 525235803
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Medchemexpress LLC NVP-BSK805 dihydrochloride | 1942919-79-0 | 99.0% | 563.47 | 25 MG
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NVP-BSK805 dihydrochloride is an ATP-competitive inhibitor primarily targeting JAK2, with high selectivity over other JAK family members like JAK1, JAK3, and TYK2. It effectively suppresses the growth of JAK2V617F-bearing acute myeloid leukemia cell lines and blocks STAT5 phosphorylation. This compound also enhances the sensitivity of drug-resistant cancer cells to certain treatments by improving P-gp inhibitory activity.
- Potent ATP-competitive JAK2 inhibitor
- Selective inhibition over JAK1, JAK3, and TYK2
- Suppresses JAK2V617F-bearing acute myeloid leukemia cell growth
- Blocks STAT5 phosphorylation
- Improves P-gp inhibitory activity
- Increases sensitization of drug-resistant cancer cells to treatments
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eMolecules 50270-27-4 | 2,4,6-Trichloropyrimidine-5-carbaldehyde | Oakwood Chemicals | MFCD02257700 | 211.430 | C5HCl3N2O | 97.000 | Clc1nc(Cl)c(C=O)c(Cl)n1 | 25g | 532639835
2,4,6-Trichloropyrimidine-5-carbaldehyde | Oakwood Chemicals | 50270-27-4 | MFCD02257700 | 211.430 | C5HCl3N2O | 97.000 | Clc1nc(Cl)c(C=O)c(Cl)n1 | 25g | 532639835
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Apexbio Technology LLC PTC209 HBr 1217022-63-3 10mM (in 1mL DMSO)
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PTC209 HBr (CAS 1217022-63-3) is the hydrobromide salt form of PTC-209 known as a selective inhibitor of BMI-1 a component of the Polycomb Repressive Complex 1 (PRC1) involved in epigenetic regulation PTC209 HBr inhibits BMI-1 with an IC50 of 0 5 M and suppresses both UTR-mediated reporter activity and endogenous BMI-1 expression in HCT116 colorectal and HT1080 fibrosarcoma cells in a dose-dependent manner independent of cytotoxic effects In vivo treatment of colorectal cancer cells with PTC209 HBr prior to xenotransplantation into mice results in reduced or arrested tumor growth This compound is utilized in studies of cancer stem cell biology and epigenetic modulation in colorectal cancer
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Aobchem AOBCHEM
5000865055 2 4 5-TRIBROMOPHENOL 1G
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Aobchem AOBCHEM
5000865044 3-BROMO-6-CHLORO-2-FLUOROPHEN
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Ambeed AMBEED
5000868693 2-3-BROMO-2-CHLOROPHENYLAC 1GR
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000701411 LACTAMIDE 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370248 ELLIPTICINE HYDROCH 25MG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000370287 HG-9-91-01 25MG
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Apexbio Technology LLC β-Interleukin I (163-171), human 106021-96-9 5mg
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beta-Interleukin I 163-171 human is a peptide fragment derived from human interleukin-1 (IL-1 ) It is utilized to investigate immune signaling pathways particularly those involved in inflammatory responses and T cell activation beta-Interleukin I 163-171 human exerts its biological activity by participating in the modulation of inflammatory signaling cascades relevant to immune system regulation Based on these pharmacological properties beta-Interleukin I 163-171 human holds research potential in the study of immune activation inflammation and associated signaling mechanisms in biomedical research
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Medchemexpress LLC Cephapirin (sodium) | 24356-60-3 | 95.7% | C17H16N3NaO6S2 | 1 ML
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Cephapirin sodium is an ephalosporin antibiotic known for its broad-spectrum antimicrobial activity. It is effective against various bacterial strains, including Staphylococcus aureus, S. epidermidis, S. viridans, S. pyogenes, and Diplococcus pneumonia.
- Appearance: White to off-white solid
- Purity: 95.74%
- Molecular weight: 445.45
- Solubility in water: ≥ 100 mg/mL (224.49 mM)
- Solubility in DMSO: 33.33 mg/mL (74.82 mM)
- Effective against Staphylococcus aureus in vivo
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Medchemexpress LLC 5-Bromo-3-pyridinol | 74115-13-2 | 952150 | 100.0% | C5H4BrNO | 10 G
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5-Bromo-3-pyridinol is a chemical and pharmaceutical intermediate used in the research of biological activities. Its chlorinated derivatives are known to be potential fungicides.
- Chemical and pharmaceutical intermediate
- Used in research of biological activities
- Chlorinated derivatives are potential fungicides
- Chlorinated derivatives provide at least 70% control of Plasmopara viticola at 200 ppm
- Derivatives can be used to control fungal infections of plants
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Aobchem AOBCHEM
5000863895 5-BROMO-3-METHYL-2- 2 2 2-TRIF
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Medchemexpress LLC Highly purified type III collagen, from bovine skin | 90.0% | 300000.00 | 1 MG
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Highly purified Type III collagen, from bovine skin, is an immune grade collagen derived from bovine skin. It is designed to stimulate the animal's immune system to produce specific antibodies against this collagen and also functions as a substrate for hydrolysis by Matrix Metalloproteinases (MMPs).
- Immune grade collagen
- Derived from bovine skin
- Stimulates specific antibody production
- Substrate for Matrix Metalloproteinase (MMP) hydrolysis
- For research use only
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