Halophenols
- (184)
- (5)
- (51)
- (1)
- (4)
- (6)
- (92)
- (2)
- (20)
- (4)
- (2)
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- (199)
- (1)
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- (219)
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- (16)
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- (28)
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- (1)
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- (5)
- (1)
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- (1)
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- (1)
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- (1)
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- (4)
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- (1)
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- (1)
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- (4)
- (1)
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- (1)
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- (7)
- (30)
- (1)
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- (1)
- (1)
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- (1)
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- (1)
- (1)
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- (1)
- (1)
- (10)
- (15)
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- (1)
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- (9)
- (4)
- (1)
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- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
- (1)
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- (3)
- (2)
- (1)
- (2)
- (1)
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- (1)
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- (8)
- (1)
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- (1)
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- (1)
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- (2)
- (4)
- (1)
- (1)
- (1)
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- (1)
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- (1)
- (23)
- (8)
- (2)
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- (1)
- (1)
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- (1)
- (1)
- (1)
- (7)
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- (2)
- (1)
- (1)
- (4)
- (5)
- (1)
- (1)
- (1)
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- (3)
- (1)
- (1)
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- (1)
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- (5)
- (1)
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- (17)
- (1)
- (3)
- (1)
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- (1)
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- (41)
- (75)
- (110)
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- (114)
- (193)
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Apexbio Technology LLC NPS-1034 1221713-92-3 50mg
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NPS-1034 (CAS 1221713-92-3) is a potent inhibitor of the receptor tyrosine kinase MET with an IC50 of 4 nmol/L MET activated by hepatocyte growth factor is implicated in morphogenesis and tumor progression across various cancers NPS-1034 suppresses cell viability in MET-overexpressing and phosphorylated MET-positive cell lines such as MKN45 and SNU638 with IC50 values of 112 7 nmol/L and 190 3 nmol/L respectively In vivo oral administration of NPS-1034 reduces tumor growth and angiogenesis in MKN45 xenograft models These characteristics support the utility of NPS-1034 in studying MET-driven oncogenic signaling and its therapeutic targeting
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BOP reagent is a peptide-coupling reagent designed to facilitate amide bond formation between amino acids BOP reagent acts by activating carboxyl groups on amino acid derivatives or peptides promoting coupling reactions under mild conditions The mechanism involves the generation of benzotriazole group-bearing intermediates that enable efficient coupling with amino-functionalized reactants Based on these chemical properties BOP reagent is utilized in peptide synthesis and in the preparation of phenyl ester derivatives of amino acids for research in biochemical and pharmaceutical fields
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