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Filtered Search Results
eMolecules 56553-60-7 | Sodium triacetoxyborohydride | Oakwood Chemical | MFCD00012211 | 211.940 | C6H10BNaO6 | 90.000 | [Na+].CC(=O)O[BH-](OC(C)=O)OC(C)=O | 1kg | 571831845
Sodium triacetoxyborohydride | Oakwood Chemical | 56553-60-7 | MFCD00012211 | 211.940 | C6H10BNaO6 | 90.000 | [Na+].CC(=O)O[BH-](OC(C)=O)OC(C)=O | 1kg | 571831845
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Medchemexpress LLC Quiflapon (sodium) | 147030-01-1 | C34H34ClN2NaO3S | 1 ML
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Quiflapon (sodium) is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor. Also known as MK-591 sodium, it is an orally active Leukotriene biosynthesis inhibitor that induces apoptosis. This analytical standard is intended for research and analytical applications, suitable for qualitative, quantitative, and methodological research experiments like HPLC, GC, and MS. It is for research use only and not intended for human use.
- Selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor
- Orally active Leukotriene biosynthesis inhibitor
- Induces apoptosis
- Acts as an analytical standard for research
- Suitable for qualitative, quantitative, and methodological experiments (HPLC, GC, MS)
- Triggers apoptosis in prostate cancer cells
- Reduces amyloid burden in Alzheimer's disease models
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Medchemexpress LLC Furamidine dihydrochloride | 55368-40-6 | 99.0% | 377.27 | 100 MG
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Furamidine dihydrochloride is a selective protein arginine methyltransferase 1 (PRMT1) inhibitor, exhibiting an IC50 of 9.4 μM. It demonstrates selectivity for PRMT1 over PRMT5, PRMT6, and PRMT4. Additionally, it functions as a potent, reversible, and competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor, effective with both single- and double-stranded DNA substrates. This compound also possesses antiparasite agent properties.
- Selective PRMT1 inhibitor
- Potent, reversible, and competitive TDP-1 inhibitor
- Effective against single- and double-stranded DNA substrates
- Acts as an antiparasite agent
- Inhibits cell growth in most leukemia cell lines (except HEL cells with JAK2V617F mutations)
- Reduces expression of methylated GFP-ALY protein in 293T cells
- Can intercalate between GC base pairs of duplex DNA
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Medchemexpress LLC Broussonin E | 90902-21-9 | 1 ML
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Broussonin E is a phenolic compound exhibiting anti-inflammatory activity. It suppresses inflammation by modulating the activation state of macrophages through inhibiting the ERK and p38 MAPK pathways, while enhancing the JAK2-STAT3 signaling pathway. This compound can be utilized for research related to inflammation-related diseases, such as atherosclerosis.
- Inhibits LPS (lipopolysaccharides)-stimulated phosphorylation of ERK and p38 MAPK at 20 μM for 3 hours.
- Activates janus kinase (JAK) 2 and signal transducer and activator of transcription (STAT) 3.
- Suppresses LPS-induced pro-inflammatory production in RAW264.7 cells (0-20 μM, 3 h), including TNF-α, IL-1β, IL-6, COX-2, and iNOS.
- Enhances the expression of anti-inflammatory mediators such as IL-10, CD206, and arginase-1 (Arg-1) in LPS-stimulated RAW264.7 cells.
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Medchemexpress LLC Trimethylphenylammonium bromide | 16056-11-4 | 98.0% | 216.12 | 250 G
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Trimethylphenylammonium bromide is a quaternary ammonium salt composed of a positively charged N,N,N-trimethylanilinium cation and a negatively charged bromide anion. It serves as a phase transfer catalyst in organic chemical reactions, aiding the transfer of reactants between immiscible phases. Additionally, it can be utilized as a reagent in the synthesis of various organic compounds and, in some applications, as a surfactant or corrosion inhibitor. It is a biochemical reagent suitable for life science research.
- Appearance: Solid
- Color: Light blue to blue
- Shipping: Room temperature in continental US; may vary elsewhere
- Storage: Powder at -20°C for 3 years, or 4°C for 2 years. In solvent, -80°C for 6 months, or -20°C for 1 month
- Solubility: In H2O: 50 mg/mL (231.35 mM; requires ultrasonic)
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Medchemexpress LLC G0-C14 | 1510653-27-6 | C106H216N10O10 | 25 MG
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G0-C14 is a cationic lipid-like compound, an alkyl-modified polyamidoamine (PAMAM) dendrimer. It is utilized in the preparation of macrophage-targeted nanoparticles (NPs) for agent and vaccine delivery.
- Strong entrapment of mRNA and pDNA with over 95% encapsulation efficiency.
- Appears as an oil.
- Colorless to light yellow in appearance.
- Purity of 98.0%.
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Medchemexpress LLC ODN 24987 sodium | DNA, d(P-thio)(C-C-T-G-G-C-c7G-G-G-G), sodium salt | 1 MG
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ODN 24987 sodium is a Guanine-modified inhibitory oligonucleotide (ODN), targeting TLR9. It can inhibit IL-6 and IFN-α release and can be used for researching immune disorders. The sequence is 5'-C-C-T-G-G-C-c7G-G-G-G-3'.
- Guanine-modified inhibitory oligonucleotide
- Targets toll-like receptor 9 (TLR9)
- Inhibits IL-6 and IFN-α release
- Suitable for immune disorder research
- Sequence: 5'-C-C-T-G-G-C-c7G-G-G-G-3'
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Medchemexpress LLC HuGAL-F2 1mg | 1mg
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HuGAL-F2 is a human-derived antibody expressed in CHO cells targeting FGF2 HuGAL-F2 contains a huIgG2 heavy chain and a hu light chain with a predicted molecular weight (MW) of 150 kDa The isotype control for HuGAL-F2 can refer to Human IgG1 kappa Isotype Control (HY-P99001)
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Medchemexpress LLC BCR-ABL1-IN-1 | 1488090-21-6 | 99.82% | C18H12F3N3O2 | 1 ML
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BCR-ABL1-IN-1 is a potent ABL1 inhibitor with an IC50 of 8.7 nM. This compound is suitable for research applications related to central nervous system (CNS) diseases. It has demonstrated effectiveness in inhibiting the proliferation of Ba/F3-BCR-ABL1-WT cells.
- Inhibitor for ABL1 (64-515)
- IC50 of 8.7 nM against ABL1
- Suitable for CNS disease research
- Inhibits Ba/F3-BCR-ABL1-WT cell proliferation with an IC50 of 30 nM
- Purity of 99.82%
- Stable under recommended storage conditions
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solution storage: -80°C for 6 months, -20°C for 1 month
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Apexbio Technology LLC Agatolimod sodium 541547-35-7 1mg
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Agatolimod sodium (CAS 541547-35-7) also known as ODN 2006 is a synthetic oligodeoxynucleotide classified as a B-type CpG ODN It selectively activates Toll-like receptor 9 (TLR9) by binding to specific CpG motifs leading to the induction of various cytokines and chemokines in immune cells This immunostimulatory activity enhances host immune responses and modulates immune function Agatolimod sodium is widely investigated as an immunomodulatory agent in preclinical and clinical research with applications as a vaccine adjuvant and in studies of antitumor and anti-infective therapies
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Medchemexpress LLC Ethanaminium, 2-(acetylthio)-N,N,N-trimethyl-, chloride (1:1) | 6050-81-3 | MFCD00038727 | 98.0% | 197.73 | C7H16ClNOS | 25 G
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Acetylthiocholine chloride is a biochemical assay substrate commonly used to measure cholinesterase activity in enzymatic and diagnostic assays. It is supplied as a white to off-white solid, characterized by NMR, and accompanied by certificate of analysis information. Store sealed and protected from moisture; when prepared in solvent, follow recommended low-temperature storage for long-term stability.
- Used as a substrate for cholinesterase activity assays.
- Purity 98.0% (NMR).
- CAS number 6050-81-3.
- Molecular weight 197.73.
- White to off-white solid appearance.
- Available in multiple sizes, including 25 g.
- Store sealed, away from moisture; in solvent, -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC Ard-2051 | 2632305-17-8 | 98.6% | 789.32 | C43H45ClN8O5 | 10 MG
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ARD-2051 is a selective, orally active androgen receptor proteolysis-targeting chimera (PROTAC) degrader developed for preclinical research into AR-dependent cancers. It induces potent AR protein degradation in cell-based assays and has demonstrated favorable pharmacokinetics and oral efficacy in animal models.
- Potent AR protein degradation (DC50 ~0.6 nM).
- Orally active with demonstrated in vivo efficacy in preclinical models.
- Effective in AR-positive prostate cancer cell lines, including LNCaP and VCaP.
- Characterized pharmacokinetic profile and oral bioavailability in rodent and canine studies.
- High chemical purity suitable for research applications.
- Supplied as a solid with defined storage recommendations for stability.
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Medchemexpress LLC Sodium methylparaben | 5026-62-0 | MFCD00016470 | 99.3% | 174.13 | C8H7NaO3 | 100 G
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Sodium methylparaben, 99% (sodium methyl 4-hydroxybenzoate) is the sodium salt of methylparaben supplied for research and analytical use as an antifungal preservative and analytical standard. It is commonly used in formulation testing and microbiological assays and shows in vitro antifungal activity against certain molds. CAS: 5026-62-0; molecular weight: 174.13.
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Medchemexpress LLC EGFR-IN-98 | 99.1% | 383.87 | 1 ML
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EGFR-IN-98 (Compound 4c) is an EGFR inhibitor that can be used in the study of tumors. It demonstrates potent inhibitory activity against various EGFR mutations. This product is provided as a solid with high purity, suitable for research applications.
- Targets EGFR, specifically mutations L858R/T790M/C797S and Del19/T790M/C797S
- High purity of 99.12%
- Molecular weight of 383.87
- Available as a solid, or in solution with DMSO
- Suitable for tumor studies
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eMolecules Oakwood Chemicals Saturated aqueous Sodium bicarbonate solution ( 9 6% wt/wt) 1kg 480155352 104315 0 000 144-55-8 MFCD00003528 84 006 CHNaO3
Oakwood Chemicals Saturated aqueous Sodium bicarbonate solution ( 9 6% wt/wt) 1kg 480155352 104315 0 000 144-55-8 MFCD00003528 84 006 CHNaO3
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