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Filtered Search Results
Medchemexpress LLC BPK-21 | 2305052-77-9 | 99.6% | C23H16Cl2F3NO2 | 1 ML
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BPK-21 is an active acrylamide that suppresses T cell activation by blocking the function of ERCC3. It specifically targets C342 in the helicase ERCC3, making it suitable for research applications related to T cell biology.
- Suppresses T cell activation
- Blocks ERCC3 function
- Specifically targets C342 in the helicase ERCC3
- Significantly impairs T cell activation at 20 μM
- Molecular weight: 466.28
- Appearance: Solid
- Color: White to off-white
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Medchemexpress LLC Interleukin-21 protein, rat | >95.0% | 500 UG
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Recombinant rat interleukin-21 supplied lyophilized for research use, expressed in E. coli and provided as a 500 μg vial. Intended for functional assays and binding studies; handle and store frozen for extended stability.
- Species: rat, recombinant protein
- Source: expressed in E. coli
- Formulation: lyophilized from PBS, pH 7.4
- Amount: 500 μg per vial
- Purity: >95.0% by reducing SDS-PAGE
- Molecular weight: ~16 kDa (reducing SDS-PAGE)
- Sequence range: P25-S146
- Recommended use: functional ELISA; reported ED50 12.16 ng/mL
- Storage: store at -20°C; freeze aliquots at -20°C or -80°C for long-term
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Apexbio Technology LLC TUG-770 1402601-82-4 25mg
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TUG-770 (CAS 1402601-82-4) is a potent agonist of the free fatty acid receptor 1 (FFA1/GPR40) a G protein-coupled receptor implicated in the enhancement of glucose-stimulated insulin secretion by pancreatic -cells TUG-770 demonstrates high affinity for FFA1 with an EC50 of 6 nM and over 150-fold selectivity compared to FFA4 as well as high selectivity over other receptors and transporters In INS-1E rat -cell lines TUG-770 promotes insulin secretion in the presence of elevated glucose Pharmacokinetic studies in mice indicate favorable oral absorption and bioavailability with dose-dependent reductions in blood glucose during glucose tolerance tests TUG-770 is a valuable tool for investigating FFA1-mediated pathways and glucose homeostasis in metabolic research
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Medchemexpress LLC C2/Complement C2 Mo 50ug
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Complement C2 is a component of the classical pathway of the complement system and is cleaved by activated factor C1 resulting in the formation of two distinct fragments C2b and C2a The subsequent serine protease activity of C2a is critical for its subsequent interaction with the complement factor C4b leading to the formation of C3 or C5 convertase C2/Complement C2 Protein Mouse (HEK293 His) is the recombinant mouse-derived C2/Complement C2 protein expressed by HEK293 with C-His labeled tag
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Cambridge Isotope Laboratories Octabromodibenzofuran (13C12 99%) 5 ug/mL in nonane toluene (70 30) 1 2 mL
Octabromodibenzofuran (13C12 99%) 5 ug/mL in nonane toluene (70 30) 1 2 mL
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Cambridge Isotope Laboratories 4 4-DDE (ring-13C12 99%) 100 ug/mL in acetonitrile 1 2 mL
4 4-DDE (ring-13C12 99%) 100 ug/mL in acetonitrile 1 2 mL
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Medchemexpress LLC Solvent blue 35 (Sudan blue II) | 17354-14-2 | 99.8% | 100 G
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Solvent Blue 35 (Sudan Blue II) is an anthraquinone-based blue solvent dye. It can be used to mark specific diesel fuels and to distinguish agricultural, fishery, and automotive fuels.
- Blue solvent dye
- Suitable for marking specific diesel fuels
- Distinguishes agricultural, fishery, and automotive fuels
- For research use only
- Solid appearance
- Purple to purplish red color
- Insoluble in water
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Medchemexpress LLC Triflumuron | 64628-44-0 | 99.0% | 100 G
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Triflumuron is a potent chitin synthesis inhibitor that shows efficacy in emergence inhibition (EI) against *Culex quinquefasciatus* and *Aedes albopictus*, with EI50 values of 5.28 and 1.59 μg/L, respectively. It can be used as an insecticide and represents a potential tool for controlling disease vectors in public health.
- Potent chitin synthesis inhibitor.
- Shows efficacy in emergence inhibition against Culex quinquefasciatus and Aedes albopictus.
- Can be used as an insecticide.
- Potential tool for controlling disease vectors in public health.
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Medchemexpress LLC GR 64349 | 137593-52-3 | MFCD00153800 | 99.9% | 921.11 | 1 MG
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GR 64349 is a potent and highly selective NK2 receptor peptide agonist with an EC50 of 3.7 nM in rat colon. This compound demonstrates selectivity of over 1000-fold with respect to NK1 receptors and over 300-fold with respect to NK3 receptors.
- Potent and highly selective NK2 receptor peptide agonist.
- Exhibits high selectivity for NK2 receptors over NK1 and NK3 receptors.
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Medchemexpress LLC Α-Helical CRF(9-41) | 90880-23-2 | 98.88% | 3826.40 | 1 MG
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Α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with a KB of ~100 nM. It also acts as a partial agonist of the CRF1 receptor with an EC50 of 140 nM.
- Competitive CRF2 receptor antagonist
- Partial agonist of CRF1 receptor
- White to off-white solid appearance
- In vitro solubility: H2O : 50 mg/mL (13.07 mM; Need ultrasonic)
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Medchemexpress LLC L-Tyrosinamide | 4985-46-0 | 98.95% | 180.20 | 25 G
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L-Tyrosinamide is a derivative of Tyrosine, which is an amino acid amide.
- Purity of 98.95%
- Molecular weight of 180.20
- Appears as a solid
- Store at 4°C under nitrogen
- Solvent storage at -80°C for 6 months or -20°C for 1 month under nitrogen
- Soluble in DMSO at 100 mg/mL
- For research use only
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Medchemexpress LLC Noggin Human CHO 100ug
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Recombinant human Noggin protein, expressed in CHO cells and supplied as a lyophilized, tag-free powder for in vitro research use. Noggin binds BMP-2/4/7 to antagonize BMP signaling and is provided with high purity and formulation components to support stability and storage.
- High purity (>95%) as determined by reducing SDS-PAGE.
- Apparent molecular weight ~27-36 kDa due to glycosylation.
- Lyophilized formulation with trehalose for improved stability.
- Mammalian expression (CHO) for relevant post-translational modifications.
- Suitable for in vitro research applications; not for clinical use.
- Multiple pack sizes available, including 100 μg.
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Medchemexpress LLC Advanced glycation end products | 1 MG
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Advanced glycation end products (AGEs) are stable compounds formed by non-enzymatic reactions of reducing sugars with proteins, lipids, or nucleic acids. They are frequently utilized as a target for assessing the inhibitory effects of anti-glycosylation compounds.
- Used for research purposes
- Supplied as a liquid
- Light yellow to yellow appearance
- Concentration of 50 mg/mL
- Formulated in 0.01 M PBS, pH 7.4
- Store at -20°C for 2 years
- Not classified as a hazardous substance or mixture
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Medchemexpress LLC Highly purified type III collagen, from bovine skin | 90.0% | 300000.00 | 1 MG
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Highly purified Type III collagen, from bovine skin, is an immune grade collagen derived from bovine skin. It is designed to stimulate the animal's immune system to produce specific antibodies against this collagen and also functions as a substrate for hydrolysis by Matrix Metalloproteinases (MMPs).
- Immune grade collagen
- Derived from bovine skin
- Stimulates specific antibody production
- Substrate for Matrix Metalloproteinase (MMP) hydrolysis
- For research use only
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Apexbio Technology LLC Lansoprazole sodium 226904-00-3 10mM (in 1mL Ethanol)
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Lansoprazole sodium is a small-molecule inhibitor targeting gastric H /K -ATPase and several human cytochrome P450 (CYP) isoforms including CYP2C9 and CYP2C19 It is designed to inhibit acid secretion by selectively modulating H /K -ATPase activity in parietal cells and to modulate CYP-mediated metabolism pathways Lansoprazole sodium exerts its biological activity primarily through inhibition of its targets In human liver microsome studies it inhibits CYP2C9 and CYP2C19 with Ki values of approximately 21 M and 1 M respectively its inhibitory effect on CYP2D6 and CYP3A4 is weaker with IC values above 200 M Based on these pharmacological properties Lansoprazole sodium holds research potential in the investigation of gastric acid secretion disorders and drug drug interaction profiles involving CYP-mediated metabolism
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