Halophenols
![Apexbio Technology LLC vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus] 25mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000063054.png-250.jpg)
Apexbio Technology LLC vitamin D binding protein precrusor (208-218) [Homo sapiens]/[Oryctolagus cuniculus] 25mg
Vitamin D binding protein (DBP) precursor (208-218) peptide fragment is derived from the multifunctional serum protein DBP a major plasma protein involved in the systemic transport of vitamin D metabolites DBP facilitates the delivery and bioavailability of vitamin D and its metabolites within tissues thereby influencing calcium homeostasis and bone mineral metabolism Additionally DBP exhibits roles in immunomodulation and innate immune responses The peptide segment from residues 208-218 corresponds specifically to a conserved region known for its functional and binding attributes in humans and rabbit species This peptide fragment serves as a research tool for investigating vitamin D-related physiological pathways calcium metabolism mechanisms and immune function interactions in biomedical studies
Apexbio Technology LLC 8-Bromo-cAMP, sodium salt 76939-46-3 25mg
8-Bromo-cAMP sodium salt (CAS 76939-46-3) is a synthetic cyclic AMP analogue that influences various signal transduction pathways It primarily activates protein kinase A (PKA) and can trigger phosphorylation cascades such as ERK1/2 activation independently of Shc phosphorylation In diverse cell types this molecule modulates gene expression for instance increasing mRNA levels for chorionic gonadotropin subunits and reducing fibronectin mRNA It also enhances catecholamine synthesis via tyrosine hydroxylase phosphorylation Thus 8-Bromo-cAMP serves as a valuable reagent for examining cellular proliferation differentiation and hormonal regulation mechanisms
Apexbio Technology LLC Tetrahydrozoline HCl 522-48-5 5g
Tetrahydrozoline HCl (CAS 522-48-5) is an imidazoline-based small molecule that functions primarily as an agonist at alpha-adrenergic receptors Activation of these receptors by tetrahydrozoline elicits vasoconstriction via smooth muscle contraction reducing redness and swelling Due to this mechanism tetrahydrozoline hydrochloride is commonly utilized as a research tool to investigate alpha receptor-mediated physiological and pharmacological responses particularly in cardiovascular and ocular experimental models
Apexbio Technology LLC HyperScribe™ SP6 High Yield RNA Synthesis Kit 50rxns
The HyperScribe SP6 High Yield RNA Synthesis Kit is developed for efficient RNA generation utilizing SP6 RNA polymerase-mediated in vitro transcription The kit primarily contains recombinant SP6 RNA polymerase transcription buffer optimized for enzyme activity ribonucleotide triphosphates (NTPs ATP CTP GTP UTP) and control DNA template Each provided NTP solution exhibits 99% purity at a concentration compatible with high-yield transcription Each 20 L standard transcription reaction can produce 50 g of RNA product from 1 g control DNA template The synthesized RNA can be applied in various biomedical research fields including in vitro protein expression antisense RNA and RNA interference assays RNA-based vaccine development ribozyme biochemistry RNA-protein interaction analyses nucleic acid probe-based blotting and RNA structural-function studies
Apexbio Technology LLC Recombinant Mouse IL-3 500ug
Interleukin-3 (IL-3) is a cytokine encoded by the IL-3 gene located on chromosome 5 in mice Primarily secreted by activated T cells mast cells and epithelial cells mouse IL-3 plays roles in hematopoiesis by regulating the proliferation differentiation and function of granulocytes and monocyte-macrophage lineage cells IL-3 regulates cellular activities via interaction with the interleukin-3 receptor composed of and subunits initiating downstream intracellular signaling events Mouse IL-3 comprises 140 amino acid residues and exhibits species-specific action due to low homology with its human counterpart Recombinant Mouse IL-3 protein such as Mouse IL-3 (UniProt P01586 Ala27-Cys166) expressed in E coli without tag allows investigation into cytokine-mediated signaling and in vitro hematopoietic assays
Apexbio Technology LLC Sodium molybdate 7631-95-0 10g
Sodium molybdate is an inorganic molybdenum salt functioning as an inhibitor of acid phosphatases as well as a modulator of glucocorticoid receptor dynamics Its primary mode of action involves inhibition of various acid phosphatase enzymes including those secreted by osteoclasts thereby interfering with bone resorption processes in vitro and in vivo This molecular property allows sodium molybdate to be employed as an experimental tool in researching metabolic bone turnover and related osteoclastic activities Additionally sodium molybdate participates in the stabilization of glucocorticoid receptors by preserving the receptor in its nonactivated complex form facilitating receptor characterization and steroid hormone signaling research
Apexbio Technology LLC TNF-alpha/TNFSF2，human recombinant protein 500ug
Tumor necrosis factor-alpha (TNF- ) a cytokine belonging to the TNF superfamily is primarily produced by activated macrophages neutrophils lymphocytes NK cells endothelial cells and several transformed cell types It exists biologically as both membrane-bound and soluble homotrimeric forms interacting with two distinct receptors (TNFR1 and TNFR2) to mediate apoptotic or proliferative signaling pathways including NF- B and MAPK cascades Due to its central involvement in apoptosis inflammation immune regulation and cell differentiation recombinant human TNF- proteins have extensive applications in biomedical research such as studies on autoimmune disorders inflammation oncology and immunomodulation For instance human TNF- recombinant protein (UniProt P01375 Val77-Leu233) expressed with His-tag in E coli is frequently employed in vitro for investigating cytokine receptor signaling pathways and immune cell-mediated responses
Sigma Organic Chemistry Hydrogen hexachloroiridate(IV) hydrate | 1G | 110802-84-1 | MFCD00149906 | 99.9% trace metals basis
Hydrogen hexachloroiridate(IV) hydrate, 1G
About This Item:
Storage: room temp
Sigma Organic Chemistry Camphene | 1kg | 79-92-5 | MFCD00066603
Camphene , 1kg
About this item:
CAS #: 79-92-5
MDL #: MFCD00066603
Purity: ≥95
Molecular Weight: 136.23
UNSPSC Code: 12352100
Selleck Chemical LLC TC-H 106
TC-H 106 (Pimelic Diphenylamide 106) is a slow tight-binding inhibitor of class I histone deacetylases(HDAC) with Ki value of 148 nM about 102 nM 14 nM for HDAC1 HDAC2 HDAC3 respectively
Sigma Organic Chemistry 1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea | 25G | 107819-90-9 | MFCD00239356 | 0.98
1,3-Bis(tert-butoxycarbonyl)-2-methyl-2-thiopseudourea | 25G | 107819-90-9 | MFCD00239356 | 0.98
Sigma Organic Chemistry N-[3-(Trimethoxysilyl)propyl]aniline | 50ML | 3068-76-6 | MFCD00053673
N-[3-(Trimethoxysilyl)propyl]aniline, 50ML
About This Item:
Density: 1.07 g/mL at 25 C (lit.)
Refractive Index: n20/D 1.506 (lit.)
Storage: room temp
Sigma Organic Chemistry Potassium hexacyanoferrate(III) | 100G | 13746-66-2 | MFCD00011392 | 99.98% trace metals basis
Potassium hexacyanoferrate(III), 100G
About This Item:
Storage: room temp
EINECS Number: 237-323-3
Sigma Organic Chemistry tert-Butylchlorodimethylsilane solution | 100G | 18162-48-6 | MFCD00000501 |
tert-Butylchlorodimethylsilane solution | 100G | 18162-48-6 | MFCD00000501 |
Sigma Organic Chemistry 1-Bromo-2-cyclohexyleth | 5G | 1647-26-3 | MFCD00019398
1-Bromo-2-cyclohexyleth , 5G
About this item:
CAS #: 1647-26-3
MDL #: MFCD00019398
Purity: ≥98
Molecular Weight: 191.11
UNSPSC Code: 12352100