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Filtered Search Results
Cambridge Isotope Laboratories Isobutyl paraben (isobutyl 4-hydroxybenzoate) (ring-13C6 99%) 1 mg/mL in methanol 1 2 mL
Isobutyl paraben (isobutyl 4-hydroxybenzoate) (ring-13C6 99%) 1 mg/mL in methanol 1 2 mL
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Medchemexpress LLC Dasotraline hydrochloride | 675126-08-6 | >98.0% | 328.66 g/mol | C16H16Cl3N | 5 MG
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Dasotraline hydrochloride is the hydrochloride salt of dasotraline (SEP-225289), a triple reuptake inhibitor that blocks dopamine, norepinephrine, and serotonin transporters. It is provided for research use in biochemical and pharmacological studies of monoamine transporter inhibition.
- Triple reuptake inhibitor activity at DAT, NET, and SERT with reported low-nanomolar IC50 values.
- High purity suitable for research and analytical applications.
- Available in small mass quantities for preparation of stock solutions.
- Analytical data (HPLC, NMR) provided in accompanying documentation.
- Suitable as a reference compound in transporter and pharmacokinetic assays.
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Medchemexpress LLC (1S,2S)-2-PCCA hydrochloride | 1609563-70-3 | 99.7% | 528.56 g/mol | C30H39Cl2N3O | 5 MG
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(1S,2S)-2-PCCA hydrochloride is the (1S,2S) diastereomer of 2-PCCA supplied as the hydrochloride salt for research use. It is reported as a less active isomer compared with the active enantiomer and is used in studies of GPR88 receptor pharmacology and cAMP signaling in cell-based assays.
- Hydrochloride salt, suitable for biochemical and cell-based assays.
- CAS number 1609563-70-3.
- Molecular formula C30H39Cl2N3O; molecular weight 528.56 g/mol.
- Purity 99.7% (reported).
- Available as a solid or 10 mM solution in DMSO.
- Typical pack sizes include 5 mg.
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Medchemexpress LLC Blarcamesine hydrochloride | 195615-84-0 | MFCD30146449 | 99.9% | 317.85 g/mol | C19H24ClNO | 100 MG
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Blarcamesine hydrochloride is the hydrochloride salt of blarcamesine, an investigational small-molecule sigma-1 receptor agonist supplied for research and preclinical studies. It is provided as a high-purity solid with reported in vitro activity and specific storage recommendations. Not for human or clinical use.
- High purity solid suitable for in vitro and preclinical research.
- Sigma-1 receptor agonist with reported IC50 of 860 nM.
- Molecular formula C19H24ClNO and molecular weight 317.85 g/mol.
- White to off-white appearance for easy identification.
- Storage recommendations: store sealed, away from moisture; in solvent, -80°C (6 months) or -20°C (1 month).
- Intended for research use only; not for human use.
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Medchemexpress LLC Pimonidazole (hydrochloride) | 70132-51-3 | MFCD01700599 | 100.0% | 290.75 | C11H19ClN4O3 | 5 MG
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Pimonidazole hydrochloride is a nitroimidazole-based hypoxia marker used to label and detect hypoxic cells in tissues and cell cultures. It accumulates selectively in low-oxygen environments, enabling downstream detection by immunohistochemistry or biochemical assays. The product is supplied as a high-purity solid and should be stored sealed at recommended temperatures for stability.
- Detects and accumulates in hypoxic cells for staining and quantification.
- Suitable for immunohistochemistry, biochemical assays, and in vivo labeling.
- High purity supports reproducible experimental results.
- Available in small solid quantities appropriate for laboratory studies.
- Stable when stored sealed at recommended temperatures (short-term and long-term conditions apply).
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Medchemexpress LLC Crinecerfont hydrochloride | 321839-75-2 | MFCD05260970 | 98.0% | 519.50 g·mol⁻¹ | C27H29Cl2FN2OS | 50 MG
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Crinecerfont hydrochloride is the hydrochloride salt of crinecerfont (SSR-125543), a selective corticotropin-releasing factor type-1 (CRF1) receptor antagonist supplied as a research reagent for pharmacology and preclinical studies.
- Selective corticotropin-releasing factor type-1 (CRF1) receptor antagonist.
- Intended for pharmacology and biochemical research applications.
- Purity 98.0%.
- Molecular weight 519.50 g·mol⁻¹.
- Molecular formula C27H29Cl2FN2OS.
- Typical packaging 50 mg.
- CAS number 321839-75-2.
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Medchemexpress LLC Raxatrigine hydrochloride | 934240-31-0 | 99.1% | 1 ML
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Raxatrigine hydrochloride, also known as Vixotrigine hydrochloride, is a novel small molecule state-dependent sodium channel blocker and a Nav1.7 sodium channel inhibitor. This compound is intended for research use only.
- Inhibits Nav1.7 sodium channel
- Acts as a state-dependent sodium channel blocker
- Soluble in DMSO and water
- Compatible with various in vivo protocols
- Specific storage recommendations for solid and solution forms
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Medchemexpress LLC Dasotraline hydrochloride | 675126-08-6 | 99.0% | 10 MG
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Dasotraline hydrochloride is a triple reuptake inhibitor that effectively blocks dopamine, norepinephrine, and serotonin transporters. This compound is intended for research use only.
- Blocks dopamine, norepinephrine, and serotonin transporters
- Exhibits IC50 values of 4 nM (dopamine), 6 nM (norepinephrine), and 11 nM (serotonin)
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Medchemexpress LLC HY-078020 | 2756222-90-7 | 98.9% | 515.09 | 5 MG
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HY-078020 (compound III-4) is a selective, orally active antagonist for the histamine H1 receptor with an IC50 of 24.12 nM. It exhibits an anti-inflammatory effect in allergic diseases.
- Selective, orally active histamine H1 receptor antagonist.
- Exhibits an anti-inflammatory effect in allergic diseases.
- Potent inhibitory activity towards H1R (IC50 of 24.12 nM).
- Weak inhibition against M3R and hERG.
- Moderate permeability and good liver microsome stability.
- Long half-life in human, beagles, and mice.
- Inhibits cytochrome P450 (CYP) isozyme CYP3A4.
- Inhibits histamine-induced skin vasodilation and capillary permeability in mice.
- Exhibits weak anticholinergic activity in mice.
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Medchemexpress LLC Metipranolol hydrochloride | 36592-77-5 | 99.9% | 345.86 | 100 MG
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Metipranolol hydrochloride is a non-selective β adrenergic receptor blocking agent. It is used systemically for the treatment of arterial hypertension and topically for the management of glaucoma.
- Non-selective β adrenergic receptor blocking agent
- For research use only
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Medchemexpress LLC Rimantadine (hydrochloride) | 1501-84-4 | 98.0% | 100 G
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Rimantadine hydrochloride is an orally active inhibitor for M2 protein, blocking hydrogen ion channel activity, preventing virus entry and replication, and exhibiting broad-spectrum antiviral activity. It is intended for research use only.
- Inhibits RNA levels of hepatitis A virus (HAV) in Huh7 and IHH cells.
- Increases LC3 expression and promotes autophagy in HAV-infected Huh7 cells.
- Exhibits anti-infectious activity in H3N2-infected mouse models, lowering lung virus titer.
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Medchemexpress LLC PF-06815345 hydrochloride | 2334434-49-8 | 98.2% | 634.49 | 100 MG
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PF-06815345 hydrochloride is an orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) with an IC50 value of 13.4 μM. PF-06815345 hydrochloride significantly decreases the PCSK9 level in vivo in mouse.
- Orally active and potent inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9).
- IC50 value of 13.4 μM.
- Significantly decreases the PCSK9 level in vivo in mouse.
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Medchemexpress LLC PF-00356231 hydrochloride | 820223-77-6 | 99.5% | 464.96 | 25 MG
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PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). It forms a complex with MMP-12 and also demonstrates potency against MMP-13, MMP-8, MMP-9, and MMP-3.
- Specific inhibitor of MMP-12
- Non-peptidic, non-zinc chelating ligand
- Potent against MMP-13, MMP-8, MMP-9, and MMP-3
- For research use only
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Medchemexpress LLC Venlafaxine hydrochloride | 99300-78-4 | 99.8% | 25 MG
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Venlafaxine hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. It is an antidepressant used for research purposes only.
- Potent serotonin/norepinephrine reuptake dual inhibitor
- Antidepressant for research purposes
- Inhibits [3H]-5-HT reuptake in human SERT transfected cells (IC50: 0.2 μM)
- Inhibits [3H]-NE reuptake in human NET transfected cells (IC50: 2.55 μM)
- Inhibits human DAT expressed in HEK293 cells by neurotransmitter reuptake assay (IC50: 15700 nM)
- Dose-dependently blocks depletion of norepinephrine levels in rat hypothalamus
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Medchemexpress LLC 3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one) | 3722-51-8 | 98.4% | 212.20 | 50 G
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3-Hydroxyxanthone is a xanthone compound. It inhibits NADPH-catalysed lipid peroxidation in human umbilical vein endothelial cells (HUVECs) and also inhibits TNF-alpha induced ICAM-1 expression.
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