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Filtered Search Results
Medchemexpress LLC Plozasiran sodium | 2379776-41-5 | 97.9% | 15618.77 (free acid) | 1 MG
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Plozasiran sodium is an siRNA targeting APOC3 for the study of mixed hyperlipidemia.
- siRNA targeting APOC3
- For the study of mixed hyperlipidemia
- Appearance: Solid
- Color: White to off-white
- Shipping: Room temperature in continental US; may vary elsewhere.
- Storage: -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture).
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Medchemexpress LLC N-phenylpivalamide | 6625-74-7 | MFCD00043691 | 100.0% | 177.24 | C11H15NO | 5 G
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N-Phenylpivalamide is an organic small-molecule building block used in the synthesis of biologically active compounds. It is represented by the formula C11H15NO and has a reported CAS number 6625-74-7 and high reported purity.
- small-molecule building block for synthesis of biologically active compounds.
- chemical formula C11H15NO.
- molecular weight approximately 177.24 g/mol.
- reported high purity suitable for research applications.
- available in small-scale packages for laboratory use.
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Medchemexpress LLC DMNB | 20357-25-9 | 100.0% | 211.17 | C9H9NO5 | 25 G
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DMNB (6-nitroveratraldehyde) is a high-purity chemical intermediate used as a precursor in radiochemical synthesis, notably for preparing no-carrier-added 6-[18F]fluoro-L-DOPA for PET studies. The solid reagent is provided with analytical documentation and recommended storage to preserve stability for research applications.
- High purity: 99.98% (HPLC).
- Chemical formula C9H9NO5 and molecular weight 211.17.
- Used as a precursor for synthesis of no-carrier-added 6-[18F]fluoro-L-DOPA.
- Storage: store at 4°C under inert atmosphere; in solvent: -80°C (6 months), -20°C (1 month).
- Supplied with a certificate of analysis and safety data sheet.
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Apexbio Technology LLC RVX-208 1044870-39-4 10mM (in 1mL DMSO)
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RVX-208 (CAS 1044870-39-4) is a small-molecule inhibitor targeting BET (bromodomain and extra-terminal) proteins It is designed to selectively inhibit the binding of BET bromodomains to acetylated lysine residues thereby modulating transcriptional regulation RVX-208 exerts its biological activity primarily through competitive inhibition of the second bromodomain (BD2) of BET proteins In in vitro studies using human hepatic (HepG2) cells RVX-208 demonstrates BD2 inhibitory activity with an IC50 value of 0 51 M and lower affinity for BD1 (IC50 87 M) Based on these pharmacological properties RVX-208 holds research potential in lipid metabolism cholesterol efflux and atherosclerotic disease processes
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Apexbio Technology LLC Adrenalone HCl 62-13-5 10mM (in 1mL DMSO)
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Adrenalone hydrochloride (CAS 62-13-5) is a synthetic adrenergic agonist primarily targeting alpha-1 adrenergic receptors Through activation of these receptors Adrenalone induces vasoconstriction leading to reduced local blood flow This pharmacological property underpins its utility as a topical hemostatic agent in research settings where precise modulation of vascular tone is required Adrenalone is frequently employed to investigate adrenergic receptor signaling pathways and the physiological mechanisms underlying vascular constriction
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Apexbio Technology LLC Difloxacin HCl 91296-86-5 10mM (in 1mL DMSO)
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Difloxacin HCl (CAS 91296-86-5) is a small-molecule inhibitor targeting DNA gyrase and topoisomerase IV It is designed to interfere with DNA gyrase-mediated DNA synthesis thereby inhibiting bacterial DNA replication and cell division Difloxacin HCl exerts its biological activity primarily through inhibition of DNA gyrase and topoisomerase IV In cultured human neuroblastoma cells exhibiting multidrug resistance associated protein (MRP)-mediated chemoresistance difloxacin HCl (50 g/ml) increases cell sensitivity to MRP substrates including doxorubicin vincristine daunorubicin and potassium antimony tartrate indicating reversal of the drug-resistance phenotype Based on these pharmacological properties difloxacin HCl holds research potential in antimicrobial susceptibility testing and studies of multidrug resistance reversal
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000724428 DORAMAPIMOD HYDROCH 50MG
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Medchemexpress LLC N-(furan-2-yl(8-hydroxyquinolin-7-yl)methyl)isobutyramide | 332173-89-4 | 99.2% | 10MM 1ML
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N-(furan-2-yl(8-hydroxyquinolin-7-yl)methyl)isobutyramide | 332173-89-4 | 99.2% | 10MM 1ML
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Aobchem AOBCHEM
5000863066 2 4-DIFLUORO-6-IODOPHENOL 250M
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Alkali Scientific Benzamidine Hydrochloride, 25 G
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Benzamidine Hydrochloride is a highly pure protease inhibitor offered in a 25g package, designed for laboratory use in biochemical and molecular biology studies. It is primarily utilized to inhibit serine proteases, such as trypsin and thrombin, to protect proteins from degradation during various analytical and preparatory procedures. This reagent is essential in experiments requiring the preservation of protein structure and activity, particularly in enzyme assays, protein purification, and cell lysate preparation. Benzamidine Hydrochloride is widely applied in research focused on enzyme kinetics, protein-protein interactions, and the study of protease functions.
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Medchemexpress LLC Fuzapladib sodium | 141284-73-3 | 99.6% | 402.39 | 10 MM 1 ML
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Fuzapladib sodium | 141284-73-3 | 99.6% | 402.39 | 10 MM 1 ML
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Alkali Scientific Imipenem Monohydrate, 100 Mg
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Imipenem Monohydrate, 100 mg, is an antibiotic reagent used in microbiological research to study bacterial resistance patterns and efficacy of antibiotic treatments. As a broad-spectrum beta-lactam antibiotic, it is highly effective against a variety of both Gram-positive and Gram-negative bacterial pathogens. Imipenem inhibits the synthesis of bacterial cell walls, leading to cell death. This 100 mg concentration is used for more concentrated applications in laboratory tests, including minimal inhibitory concentration (MIC) assays and susceptibility testing. Researchers also utilize this reagent to examine resistance mechanisms and explore the use of imipenem in combination therapies against resistant strains.
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eMolecules 2-CHLORO-1-METHYLPYRIDINIU 25G
5000159953 2-CHLORO-1-METHYLPYRIDINIU 25G
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Medchemexpress LLC ASO 556089 sodium | 96.3% | 5414.60 | 1 MG
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ASO 556089 sodium is a 16 nucleotide length gapmer (3-10-3) that targets the human and mouse long non-coding RNA MALAT1, with the sequence: 5'-GmCATTmCTAATAGmCAGmC-3' (mC:5-methyl cytosine, 3 bases at 3' and 5' ends:constrained ethyl; cEt). This compound is for research use only.
- Targets PCSK9 and MALAT1 in 2D HRPTEC cultures.
- Causes target transcriptional downregulation in HRTEC cultured on chip.
- Inhibits MALAT1 gene expression in 2D HRPTEC culture.
- Does not cause cytotoxicity.
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000712117 3-METHYLTHIOPROPYL 50G
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