Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. It inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Selective inhibitor of CaM-KK
Cell-permeable
Inhibits AMPKK activity
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK). It inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 of approximately 0.02 g/ml. It is highly selective for CaM-KK without significant effect on downstream CaM kinases.
Inhibits recombinant CaM-KKα and CaM-KKβ isoforms and their autophosphorylation activities.
Has an IC50 value against CaM-KII of 10 μg/mL.
Inhibits constitutively active CaM-KKα and wild-type enzyme.
Suppresses Ca2+-induced activation of CaM-KIV in a dose-dependent manner in transfected HeLa cells.
Reduces endogenous activity of CaM-KK in SH-SY5Y neuroblastoma cells at 1μg/mL (80% inhibitory rate).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More