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Filtered Search Results
MEDCHEMEXPRESS LLC DELAMANID 5MG
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501872210 DELAMANID 5MG
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MEDCHEMEXPRESS LLC ISTRADEFYLLINE 10MG
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501872226 ISTRADEFYLLINE 10MG
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MEDCHEMEXPRESS LLC SALICYL-AMS 5MG
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501872229 SALICYL-AMS 5MG
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MEDCHEMEXPRESS LLC ZOLEDRONIC ACID MONOHYDRATE
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501872959 ZOLEDRONIC ACID MONOHYDRATE
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MEDCHEMEXPRESS LLC BML-277 10MG
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501872990 BML-277 10MG
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MEDCHEMEXPRESS LLC L-655708 5MG
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501873030 L-655708 5MG
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MEDCHEMEXPRESS LLC ETC-159 5MG
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501873713 ETC-159 5MG
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MEDCHEMEXPRESS LLC AB-MECA 5MG
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501873729 AB-MECA 5MG
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MEDCHEMEXPRESS LLC VALGANCICLOVIR HYDROCHLORIDE
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501873998 VALGANCICLOVIR HYDROCHLORIDE
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MEDCHEMEXPRESS LLC TIPIFARNIB 5MG
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501872120 TIPIFARNIB 5MG
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MEDCHEMEXPRESS LLC 5 -DEOXYADENOSINE 5MG
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501872484 5 -DEOXYADENOSINE 5MG
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Medchemexpress LLC Thalidomide-NH-CBP/p300 ligand 2 | 2484739-21-9 | 98.6% | C48H57F2N11O6 | 10MG
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Thalidomide-NH-CBP/p300 ligand 2 is a thalidomide-based PROTAC small molecule designed to induce proteasomal degradation of the transcriptional coactivators CBP and p300. It couples a thalidomide-derived E3 ligase recruiting moiety to a CBP/p300-binding ligand and is provided as a light yellow solid for research use.
- Induces proteasomal degradation of CBP and p300.
- Employs a thalidomide-derived E3 ligase recruiting moiety.
- Designed for use in cellular and mechanistic research applications.
- High purity suitable for research (reported ~98.6%).
- Provided as a light yellow solid with molecular weight ~922.03 g·mol⁻¹.
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Medchemexpress LLC Ym-53601 | 182959-33-7 | 99.4% | 372.86 g·mol⁻¹ | C21H22ClFN2O | 1 MG
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YM-53601 is a small-molecule squalene synthase (FDFT1) inhibitor used in biochemical and pharmacology research to modulate cholesterol and triglyceride biosynthesis. It has demonstrated lipid-lowering effects in vivo and is supplied as a solid or as ready-to-use DMSO solutions for laboratory assays.
- Inhibits squalene synthase (FDFT1) with reported IC50 ≈ 79 nM.
- Reduces plasma cholesterol and triglyceride levels in animal studies.
- Useful for studying lipid metabolism and hepatitis C virus propagation.
- Available as solid and 10 mM DMSO solution for assay flexibility.
- High purity suitable for biochemical and pharmacological assays.
- Comes with QC documents such as data sheet, SDS, COA, HNMR, and LCMS.
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Medchemexpress LLC Losartan Carboxylic Acid | 124750-92-1 | 99.5% | 10 MG
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Losartan Carboxylic Acid (E-3174) is an active carboxylic acid metabolite of Losartan, functioning as an angiotensin II receptor type 1 (AT1) antagonist. It blocks angiotensin II-induced responses in vascular smooth muscle cells and elevates plasma renin activities while reducing mean arterial pressure.
- Blocks angiotensin II-induced responses in vascular smooth muscle cells.
- Elevates plasma renin activities.
- Reduces mean arterial pressure.
- Inhibits specific binding of angiotensin II to vascular smooth muscle cells with an IC50 of 1.1 nM.
- Abolishes angiotensin II-induced formation of inositolphosphates in vascular smooth muscle cells.
- Inhibits angiotensin II-induced elevation of intracellular cytosolic Ca2+ concentration with an IC50 of 5 nM.
- Inhibits angiotensin II-induced cell protein synthesis with an IC50 of 3 nM.
- Induces an 87±4% inhibition of pressor responses to angiotensin I in mongrel dogs at 0.1 mg/kg.
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eMolecules 6338-45-0 | 1,4-DIMETHYLIMIDAZOLE | AstaTech | MFCD02660800 | 96.133 | C5H8N2 | 95.000 | Cc1cn(C)cn1 | 0.25g | 261434247
1,4-DIMETHYLIMIDAZOLE | AstaTech | 6338-45-0 | MFCD02660800 | 96.133 | C5H8N2 | 95.000 | Cc1cn(C)cn1 | 0.25g | 261434247
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