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Filtered Search Results
Apexbio Technology LLC Linsitinib(Synonyms: OSI-906, ASP7487, IGF-1R inhibitor OSI-906, IGF-1R/IR inhibitor OSI-906, OSI906), 5mg, CAS: 867160-71-2.
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Linsitinib (CAS 867160-71-2) also known as OSI-906 is a small-molecule inhibitor targeting both insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) kinases It exhibits potent inhibitory effects with IC50 values of 75 nM against IR and 35 nM against IGF-1R In vitro studies using the 3T3/hulGF-1R (LISN) cell line demonstrate that Linsitinib inhibits IGF-1R ligand-dependent autophosphorylation and downstream signaling via pERK1/2 pAKT and p-p70S6K It shows antiproliferative activity across multiple cancer cell lines and exhibits dose-dependent tumor growth inhibition in LISN xenograft animal models supporting its utility in oncology research
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000433266 5-NITROIMIDAZOLE 100G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000301484 PYRAZINE-2 3-DICARBO 100G
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Medchemexpress LLC 9-fluorenylmethyl carbazate | 35661-51-9 | MFCD00239419 | 99.9% | 254.28 g/mol | C15H14N2O2 | 10 G
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9-Fluorenylmethyl carbazate is a fluorescent labeling reagent used for derivatization and fluorimetric detection of glycans and other analytes. It is supplied for research use and is suitable for HPLC derivatization and fluorescence-based assays.
- Fluorimetric reagent for glycan detection and HPLC derivatization.
- High purity: 99.9%.
- Chemical formula C15H14N2O2; molecular weight 254.28 g/mol.
- Available in multiple pack sizes, including 10 g.
- Stable under recommended refrigerated or frozen storage conditions.
- Intended for research use only.
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EMPOWER MATERIALS INC QPAC-40 POLY PROPYL CARB 20KG
NC3787019 QPAC-40 POLY PROPYL CARB 20KG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
5000449202 METHYL TRIDECANOATE 10G
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Medchemexpress LLC 6-O-METHYL GUANOSINE 50MG
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501872343 6-O-METHYL GUANOSINE 50MG
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eMolecules 1-OCTYL-1H-IMIDAZOLE 1G
5000158967 1-OCTYL-1H-IMIDAZOLE 1G
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eMolecules Medchem Express / Chembridge-5861528 / 5mg / 446264941 / HY-15065 / / 332117-28-9 / MFCD01993436 / 369.425 / C19H23N5O3
Medchem Express / Chembridge-5861528 / 5mg / 446264941 / HY-15065 / / 332117-28-9 / MFCD01993436 / 369.425 / C19H23N5O3
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431842 TERT-BUTYL 4- 2-CARB 1G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
5000446922 PYRIDINE-3 5-DICARBO 50G
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Medchemexpress LLC HY-B0764A 50mg Medchemexpress, Bucladesine (calcium salt) CAS:938448-87-4 Purity:>98%
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Medchemexpress, HY-B0764A 50mg Bucladesine (calcium salt) CAS:938448-87-4 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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eMolecules Medchem Express / L-778123 (hydrochloride) / 5mg / 446267313 / HY-16273A / / 253863-00-2 / MFCD09970379 / 442.340 / C22H21Cl2N5O
Medchem Express / L-778123 (hydrochloride) / 5mg / 446267313 / HY-16273A / / 253863-00-2 / MFCD09970379 / 442.340 / C22H21Cl2N5O
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Apexbio Technology LLC 3,3',5'-Triiodo-L-thyronine 5817-39-0 5mg
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33p5p-Triiodo-L-thyronine (CAS 5817-39-0) is a thyroid hormone metabolite that acts primarily in the cytoplasm by activating a truncated thyroid receptor form (TR 1) which lacks nuclear localization capability It modulates cytoplasmic thyroid hormone receptor pathways and contributes to actin filament polymerization in neuronal and astrocytic cell populations 33p5p-Triiodo-L-thyronine exhibits its biological effects through non-classical signaling mechanisms In primary cultures of neuronal and astrocytic models it induces cytoskeletal remodeling events such as actin polymerization Based on these pharmacological properties 33p5p-Triiodo-L-thyronine serves as a research tool in neuroscience and endocrine studies focused on cytoplasmic thyroid hormone signaling and cellular morphology
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Medchemexpress LLC AICAR PHOSPHATE 50MG
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501872872 AICAR PHOSPHATE 50MG
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