Oxazoles
Medchemexpress LLC Pomalidomide-CO-C5-Br | 2227423-38-1 | 450.28 | 250 MG
Pomalidomide-CO-C5-Br is a conjugated compound derived from the E3 ligand Pomalidomide and a linker. It is designed for synthesizing highly effective PROTAC molecules, specifically those targeting ADC. This product is intended for research use only.
- Conjugated E3 ligand Pomalidomide compound.
- Used to synthesize PROTAC molecules.
- Targets ADC.
- Available as a solid, white to light yellow in appearance.
- Stable for 3 years at -20°C as powder.
- Stable for 6 months at -80°C in solvent.
Medchemexpress LLC Pomalidomide-C6-O-C5-O-C4-COOH | 2375774-54-0 | 98.6% | 559.65 | 100 MG
Pomalidomide-C6-O-C5-O-C4-COOH is an E3 ligase ligand-linker conjugate, utilized in the synthesis of PROTACs. It comprises a Pomalidomide-based cereblon ligand and a linker.
- E3 ligase ligand-linker conjugate
- Comprises a cereblon ligand and a linker
- Used for the synthesis of PROTACs
Medchemexpress LLC 2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride | 72830-09-2 | 99.7% | 224.087 | 25 G
2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride is a biochemical reagent. It can be utilized as a biological material or an organic compound for life science-related research.
- Biochemical reagent
- Suitable for life science related research
- Purity: 99.70%
Medchemexpress LLC 4-(Chloromethyl)-7-hydroxycoumarin | 25392-41-0 | 98.01% | C10H7ClO3 | 1 ML
4-(Chloromethyl)-7-hydroxycoumarin is a hydroxycoumarin derivative exhibiting potent antioxidant effects and high hydroxyl radical-scavenging properties. It contains a methyl group and a chlorine group within its heterocyclic ring and has been investigated as a potent inhibitor of zinc enzyme carbonic anhydrase isoforms CA IX and XII.
- Potent antioxidant effect
- High hydroxyl radical-scavenging property
- Investigated as inhibitors of tumor-associated carbonic anhydrase isoforms CA IX and XII
Medchemexpress LLC An-12-h5 | 1193340-31-6 | 98.0% | 5 MG
AN-12-H5 is a small-molecule antienterovirus research compound that inhibits replication of poliovirus (PV) and enterovirus 71 (EV71). It is supplied for in vitro research use and includes recommended solubility and storage conditions.
- Antienterovirus compound targeting replication of PV and EV71.
- Purity 98.0%.
- Molecular formula C24H23N3O4S3 and molecular weight 513.65 g/mol.
- Soluble in DMSO at 100 mg/mL; may require ultrasonic treatment.
- Storage: powder -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (6 months) or -20°C (1 month).
- For research use only; not for human or clinical applications.
Medchemexpress LLC (S)-1-tert-butyl 2-methyl 4-oxopiperidine-1,2-dicarboxylate | 756486-14-3 | MFCD12547027 | 97.0% | 257.28 g/mol | C12H19NO5 | 250 MG
AN-12-H5 intermediate-2 (CAS 756486-14-3) is a synthetic small-molecule intermediate used in the synthesis of the viral inhibitor AN-12-H5 and as a building block for antibody-drug conjugate (ADC) development. It is supplied as a solid with reported purity ≥97.0% and is intended for research and medicinal chemistry applications.
- High purity: ≥97.0%.
- Solid form supplied in small research pack sizes.
- Intended application: intermediate for small-molecule synthesis and ADC preparation.
- Typical pack sizes: 50 mg-1 g (research quantities).
- Storage guidance: pure form typically stored at -20°C; in solvent at -80°C.
Medchemexpress LLC Mal-C5-N-bis(PEG2-C2-acid) | 3026691-12-0 | 96.3% | 530.57 | C24H38N2O11 | 25mg
Mal-C5-N-bis(PEG2-C2-acid) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]
Medchemexpress LLC VISTA/B7-H5 Rat HE 500ug
VISTA/B7-H5 protein an immunoregulatory receptor inhibits T-cell response and may regulate embryonic stem cell differentiation by inhibiting BMP4 signaling It also stimulates MMP14-mediated MMP2 activation suggesting a role in matrix metalloproteinase processes These roles highlight the significance of VISTA/B7-H5 in immune regulation embryonic development and extracellular matrix dynamics VISTA/B7-H5 Protein Rat (HEK293 Fc) is the recombinant rat-derived VISTA/B7-H5 protein expressed by HEK293 with C-hFc labeled tag
Medchemexpress LLC AN-12-H5 intermediate-1 | 254882-14-9 | 99.7% | 259.30 | 50 MG
AN-12-H5 intermediate-1 is a compound primarily used in the synthesis of the viral inhibitor AN-12-H5 and for developing Antibody-Drug Conjugates (ADCs). The viral inhibitor AN-12-H5 specifically targets the replication of Poliovirus (PV) and Enterovirus 71 (EV71).
- Precursor for viral inhibitor synthesis.
- Applicable in antibody-drug conjugate (ADC) development.
- Exhibits high purity for research use.
Medchemexpress LLC TCS 2510 | 346673-06-1 | 98.3% | 383.49 | 1 ML
TCS 2510 is a selective EP4 agonist. It can be used for the research of metabolic diseases. This product is for research use only and not sold to patients.
- Stimulates glucagon like peptide 1 secretion in GLUTag cells.
- Activates the Gas signaling pathway.
- Increases Gcg mRNA expression levels in GLUTag cells.
- Produces a concentration-dependent increase in cAMP levels.
- Elevates plasma glucagon like peptide 1 levels in fasted mice.