Oxazoles
Medchemexpress LLC Trans-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride | 129830-38-2 | MFCD03490488 | 99.9% | 320.26 | C14H23Cl2N3O | 100 MG
Y-27632 dihydrochloride is an ATP-competitive inhibitor of Rho-associated kinases used as a research reagent to probe ROCK signaling pathways. Provided as the dihydrochloride salt, it has reported Ki values for ROCK-I and ROCK-II and is suitable for biochemical and cell-based assays investigating neuronal differentiation, epilepsy models, and fibrosis.
- ATP-competitive ROCK inhibitor with defined Ki values for ROCK-I and ROCK-II.
- High reported purity for reliable assay performance.
- Available in multiple pack sizes, including 100 mg, for flexible experimental use.
- Applicable in biochemical and cell-based assays, including neuronal differentiation studies.
- Stable when stored sealed at 4°C according to handling recommendations.
FUJIFILM BIOSCIENCES INC CultureSure Y-27632
Y-27632 is reagent for cell culture applications including human ES/iPS cell culture It enhances cell viability and reduces cell death during passaging and cryopreservation Y-27632 is selective and potent ROCK inhibitor Y-27632 plays various roles including contraction of vascular smooth muscle cells via ROCK signaling pathways Furthermore it suppresses the cell death of human embryonic stem cells hESCs and human induced Pluripotent Stem Cells hiPSCs at cell dispersion and that it increases the survival rate of hESCs and hiPSCs during cryopreservation
Selleck Chemical LLC Y-27632 2HCl S1049-1g
Y-27632 2HCl is a selective ROCK1 and ROCK2 inhibitor with a Ki of 140 nM and 300nM in a cell-free assay exhibits 200-fold selectivity over other kinases including PKC cAMP-dependent protein kinase MLCK and PAK