Oxazoles
Apexbio Technology LLC Y-320 288250-47-5 10mg
Y-320 (CAS 288250-47-5) is a phenylpyrazoleanilide small molecule immunomodulator that inhibits interleukin-17 (IL-17) production in CD4 T cells stimulated by IL-15 exhibiting an IC50 of 20 60 nM In vivo oral administration of Y-320 (0 3 3 mg/kg) reduces IL-17 mRNA expression and suppresses the progression of collagen-induced arthritis (CIA) in mice with additional efficacy observed in cynomolgus monkey CIA models Combination with anti-TNF- monoclonal antibody yields a synergistic effect Y-320 serves as a valuable tool for studying IL-17-mediated inflammatory pathways and for preclinical research in rheumatoid arthritis and related autoimmune diseases
Medchemexpress LLC Raf1 protein, human (Y340D, Y341D, sf9, His, GST) | ≥80.0% | 10UG
Recombinant human RAF1 protein containing Y340D and Y341D activating mutations. Produced in Sf9 insect cells and expressed with N-terminal His and GST tags, this kinase fragment (residues S306-F648) is supplied as a filtered solution formulated in 50 mM HEPES pH 7.5, 200 mM NaCl, 20% glycerol, and 1 mM DTT. It is designed for biochemical assays and studies of MAPK/ERK signaling.
- Activating Y340D and Y341D mutations enhance kinase activity.
- Expressed in Sf9 insect cells for eukaryotic folding and modifications.
- N-terminal His and GST tags facilitate purification and detection.
- Supplied as a ready-to-use filtered solution; no reconstitution required.
- Formulated for stability with 20% glycerol and a reducing agent.
- Suitable for kinase assays, signaling studies, and protein-protein interaction experiments.
- Store at -80°C and avoid repeated freeze-thaw cycles.
eMolecules 4570-45-0 | Oxazol-2-amine | ChemScene | MFCD07364485 | 84.078 | C3H4N2O | 96.000 | Nc1ncco1 | 25g | 536834866
Oxazol-2-amine | ChemScene | 4570-45-0 | MFCD07364485 | 84.078 | C3H4N2O | 96.000 | Nc1ncco1 | 25g | 536834866
Aobchem 4-(5 5-Dimethyl-1 3 2-dioxaborinan-2-yl)-3-methyl-benzonitrile | ≥97% | CAS 2231089-47-5 | C13H16BNO2 | 1g
4-(5 5-Dimethyl-1 3 2-dioxaborinan-2-yl)-3-methyl-benzonitrile | ≥97% | CAS 2231089-47-5 | C13H16BNO2 | 1g
Aobchem 4-(5 5-Dimethyl-1 3 2-dioxaborinan-2-yl)-3-methyl-benzonitrile | ≥97% | CAS 2231089-47-5 | C13H16BNO2 | 250mg
4-(5 5-Dimethyl-1 3 2-dioxaborinan-2-yl)-3-methyl-benzonitrile | ≥97% | CAS 2231089-47-5 | C13H16BNO2 | 250mg
Aobchem 3-[(2 4-Difluorophenoxy)methyl]benzonitrile | 97% | CAS 1019128-43-8 | C14H9F2NO | 10g
3-[(2 4-Difluorophenoxy)methyl]benzonitrile | 97% | CAS 1019128-43-8 | C14H9F2NO | 10g
Aobchem (4-((2 3-Difluorophenoxy)methyl)phenyl)boronic acid | 97% | CAS 1312811-55-4 | C13H11BF2O3 | 5g
(4-((2 3-Difluorophenoxy)methyl)phenyl)boronic acid | 97% | CAS 1312811-55-4 | C13H11BF2O3 | 5g
Aobchem 1-(3 5-Difluorophenoxy)-2-methylpropan-2-ol | 97% | CAS 1340190-63-7 | C10H12F2O2 | 1g
1-(3 5-Difluorophenoxy)-2-methylpropan-2-ol | 97% | CAS 1340190-63-7 | C10H12F2O2 | 1g
Aobchem Methyl 2-(2 4-difluorophenoxy)-2-methylpropanoate | 95% | CAS 1267527-25-2 | C11H12F2O3 | 5g
Methyl 2-(2 4-difluorophenoxy)-2-methylpropanoate | 95% | CAS 1267527-25-2 | C11H12F2O3 | 5g
Aobchem 1 5-Dibromo-2 4-dimethyl-3-nitrobenzene | 95% | CAS 90221-68-4 | C8H7Br2NO2 | 250mg
1 5-Dibromo-2 4-dimethyl-3-nitrobenzene | 95% | CAS 90221-68-4 | C8H7Br2NO2 | 250mg
Aobchem 1-(3-Ethyl-5-methoxyphenyl)-1-propanone | 95% | CAS 1806553-65-0 | C12H16O2 | 250mg
1-(3-Ethyl-5-methoxyphenyl)-1-propanone | 95% | CAS 1806553-65-0 | C12H16O2 | 250mg
Aobchem 2-Formyl-4-methoxyphenyl acetate | 97% | CAS 62536-85-0 | C10H10O4 | 250mg
2-Formyl-4-methoxyphenyl acetate | 97% | CAS 62536-85-0 | C10H10O4 | 250mg
Aobchem 1-(3-Methoxyphenyl)cyclobutanol | ≥95% | CAS 1202643-83-1 | C11H14O2 | 500mg
1-(3-Methoxyphenyl)cyclobutanol | ≥95% | CAS 1202643-83-1 | C11H14O2 | 500mg
Aobchem Ethyl(4-methoxyphenyl)sulfane | ≥97% | CAS 7205-58-5 | C9H12OS | 250mg
Ethyl(4-methoxyphenyl)sulfane | ≥97% | CAS 7205-58-5 | C9H12OS | 250mg