Pyrazoles
eMolecules 1-(Hydroxyethyl)pyrazole-4-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | 1040377-08-9 | MFCD12033564 | 238.090 | C11H19BN2O3 | 95.000 | CC1(C)OB(OC1(C)C)c1cnn(CCO)c1 | 10g | 600820776
1-(Hydroxyethyl)pyrazole-4-boronic Acid Pinacol Ester | Accela ChemBio (ASD) | 1040377-08-9 | MFCD12033564 | 238.090 | C11H19BN2O3 | 95.000 | CC1(C)OB(OC1(C)C)c1cnn(CCO)c1 | 10g | 600820776
eMolecules 4-Methyl-6-nitro-1H-indazole | 885520-77-4 | MFCD07781465 | 1g
Combi-Blocks | 4-Methyl-6-nitro-1H-indazole | 1g | 388721695 | SH-6633 | 95.000 | 885520-77-4 | MFCD07781465 | 177.163 | C8H7N3O2
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eMolecules Ambeed / 2-Chloro-34-dimethylpyridine / 250mg / 552713545 / A348580 / / 72093-11-9 / MFCD16610314 / 141.600 / C7H8ClN
Ambeed / 2-Chloro-34-dimethylpyridine / 250mg / 552713545 / A348580 / / 72093-11-9 / MFCD16610314 / 141.600 / C7H8ClN
Chem-Impex International, Inc. 1-Methyl-1H-indazole-4-carbaldehyde | MFCD10699167 | 100MG
1-Methyl-1H-indazole-4-carbaldehyde, MFCD10699167, 100MG
Medchemexpress LLC 1,3-Dimethylpyrazole | 694-48-4 | 96.13 | 1 G
1,3-Dimethylpyrazole is a bioactive compound isolated from Moso Bamboo Root. It is an active small molecule that can be used as a building block for the synthesis of multiple compounds.
Apexbio Technology LLC SU 4312 5812-07-7 10mM (in 1mL DMSO)
SU 4312 (CAS 5812-07-7) is a racemic mixture comprising both (Z)- and (E)-isomers each exhibiting distinct receptor tyrosine kinase inhibitory profiles The (Z)-isomer selectively inhibits platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor 2 (VEGFR2/FLK-1) while the (E)-isomer targets PDGFR VEGFR2 epidermal growth factor receptor (EGFR) human epidermal growth factor receptor 2 (HER-2) and insulin-like growth factor 1 receptor (IGF-1R) SU 4312 is widely employed in studies investigating tumor angiogenesis cellular signal transduction pathways and the development of targeted therapies in cancer research
eMolecules Pharmablock / 4-bromo-1H-pyrazole-3-carbonitrile / 25mg / 599151773 / PB125335 / 0.000 / 288246-16-2 / MFCD00105683 / 171.985 / C4H2BrN3
Pharmablock / 4-bromo-1H-pyrazole-3-carbonitrile / 25mg / 599151773 / PB125335 / 0.000 / 288246-16-2 / MFCD00105683 / 171.985 / C4H2BrN3
![Medchemexpress LLC 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000236420.png-250.jpg)
Medchemexpress LLC 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2-phenyl-1(2H)-phthalazinone | 880487-62-7 | MFCD28399120 | 98.0% | 317.34 | C18H15N5O | 50MG
Phthalazinone pyrazole is a potent, selective, orally active small-molecule inhibitor of Aurora-A kinase intended for laboratory research. It arrests mitosis and induces apoptosis in proliferating cells, and has been reported to modulate epithelial-mesenchymal transition during cellular differentiation. Supplied as a high-purity solid for biochemical and cellular studies.
- Potent Aurora-A kinase inhibitor (IC50 = 0.031 μM).
- Demonstrated cellular activity in multiple cancer cell lines (MCF7 IC50 1.6 μM; COLO 205 IC50 2.9 μM; HCT-116 IC50 7.8 μM).
- High purity (98.0%).
- Molecular weight 317.34; formula C18H15N5O.
- Supplied as a brown to gray solid; recommended solvent DMSO (≥ 11.11 mg/mL).
- Store solid at 4°C protected from light; in solution store at -80°C for long-term stability.
eMolecules 3-Indazolinone | 7364-25-2 | 1G | Purity: 95%
Combi-Blocks | 3-Indazolinone | 1G | 7364-25-2 | MFCD00005685
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Medchemexpress LLC RuvC E.coli His-SU 50ug
RuvC Protein, E. coli (His-SUMO) is a lyophilized recombinant endonuclease derived from Escherichia coli that processes Holliday junctions during homologous recombination. The protein is supplied with an N-terminal SUMO and 6xHis tag, and is provided with quality data including purity and endotoxin testing to support molecular biology and biochemical applications.
- Recombinant endonuclease expressed in E. coli with N-terminal SUMO and 6xHis tags.
- Lyophilized powder formulation for long-term storage and transport.
- Purity of at least 90% as determined by reducing SDS-PAGE.
- Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
- Formulated in PBS with trehalose for stability after lyophilization.
- Recommended reconstitution concentration of at least 100 μg/mL to preserve activity.
- Stable storage options include -20°C (lyophilized) and -80°C for long-term aliquots.
eMolecules 7-METHYL-6-NITRO-1H-INDAZOLE | 208457-81-2 | MFCD16620021 | 1g
AstaTech | 7-METHYL-6-NITRO-1H-INDAZOLE | 1g | 206681316 | 66074 | 95.000 | 208457-81-2 | MFCD16620021 | 177.163 | C8H7N3O2
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Medchemexpress LLC Phenol, 4-(di-1H-indol-3-ylmethyl)- | 151358-47-3 | 98.1% | 338.40 | 10 MG
DIM-C-pPhOH is a nuclear receptor 4A1 (NR4A1) antagonist. It inhibits cancer cell growth and mTOR signaling, while inducing apoptosis and cellular stress. This compound has been shown to reduce cell proliferation in various cell lines.
- Significantly decreases cell proliferation
- Induces apoptosis and cleavage of caspases 7 and 8
- Inhibits NR4A1-regulated expression of survivin, bcl-2, and EGFR
- Activates AMPKα and inhibits activation of mTOR and downstream kinases
- Decreases expression of β1-integrin protein and mRNA
- Inhibits migration of breast cancer cell lines
- Significantly inhibits tumor growth in an animal model
Chem-Impex International, Inc. 5-Amino-1,3-dimethylpyrazole | MFCD00051651 | 1G
5-Amino-1,3-dimethylpyrazole, MFCD00051651, 1G
eMolecules Ethyl 4-amino-1h-pyrazole-5-carboxylate | 55904-61-5 | MFCD06739331 | 1g
Combi-Blocks | Ethyl 4-amino-1h-pyrazole-5-carboxylate | 1g | 448003360 | QH-0758 | 97.000 | 55904-61-5 | MFCD06739331 | 155.157 | C6H9N3O2
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Medchemexpress LLC 3-Methylpyrazole | 1453-58-3 | 99.54% | C4H6N2 | 100 G
3-Methylpyrazole is utilized as a nitrification inhibitor to impede the nitrification process in soil, and has been shown to inhibit the metabolism of MAM by rat liver microsomes. For optimal stability, store the pure form at -20°C for 3 years or 4°C for 2 years. If in solvent, store at -80°C for 6 months or -20°C for 1 month.
- Purity of 99.54%
- Molecular weight of 82.11
- Appears solid below 36.5°C and liquid above 36.5°C
- Color is light yellow to reddish brown
- Solubility in H₂O of 25 mg/mL (304.48 mM), requiring ultrasonic
- Solubility in PBS of 50 mg/mL (608.97 mM), forming a clear solution and requiring ultrasonic
- Inhibits the metabolism of MAM by rat liver microsomes