Pyrazoles
eMolecules 2H-Pyrazole-3-carboxylic acid | 797027-83-9 | 250MG
Chem-Impex | 2H-Pyrazole-3-carboxylic acid | 250MG | 797027-83-9 | MFCD04629633 | MW:103.12
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eMolecules 3,5-DINITRO-1H-PYRAZOLE | 38858-89-8 | MFCD06618360 | 1g
AstaTech | 3,5-DINITRO-1H-PYRAZOLE | 1g | 302798341 | F12439 | 95.000 | 38858-89-8 | MFCD06618360 | 158.073 | C3H2N4O4
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Medchemexpress LLC Propyl pyrazole triol | 263717-53-9 | MFCD03453628 | 99.1% | 386.44 g·mol⁻¹ | C24H22N2O3 | 25 MG
Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist used in biochemical and cellular research to probe ERα-mediated signaling. It is a small-molecule phenolic compound with high selectivity for ERα over ERβ and is supplied as a solid for laboratory use. For research and analytical applications only; not for human use.
- Selective ERα agonist for receptor-specific studies.
- High ERα versus ERβ selectivity supported by binding data.
- CAS number 263717-53-9 for unambiguous identification.
- Molecular formula C24H22N2O3 and molecular weight 386.44 g·mol⁻¹.
- Supplied as a solid powder suitable for solution preparation.
- Intended for research and analytical applications only.
Apexbio Technology LLC DIM-C-pPhOH 151358-47-3 25mg
DIM-C-pPhOH (CAS 151358-47-3) is a small-molecule antagonist that targets the nuclear receptor NR4A1 (nuclear receptor subfamily 4 group A member 1) It has been shown to inhibit tumor cell proliferation by modulating the mTOR signaling pathway induce apoptosis and activate cellular stress responses In in vitro studies using human renal carcinoma cell lines ACHN and 786-O DIM-C-pPhOH demonstrated inhibitory effects on cell proliferation with IC50 values of 13 6 M and 13 0 M respectively This compound serves as a valuable tool for investigating tumor-associated signaling pathways and the mechanisms underlying anticancer therapeutics
Apexbio Technology LLC DIM-C-pPhOH 151358-47-3 10mg
DIM-C-pPhOH (CAS 151358-47-3) is a small-molecule antagonist that targets the nuclear receptor NR4A1 (nuclear receptor subfamily 4 group A member 1) It has been shown to inhibit tumor cell proliferation by modulating the mTOR signaling pathway induce apoptosis and activate cellular stress responses In in vitro studies using human renal carcinoma cell lines ACHN and 786-O DIM-C-pPhOH demonstrated inhibitory effects on cell proliferation with IC50 values of 13 6 M and 13 0 M respectively This compound serves as a valuable tool for investigating tumor-associated signaling pathways and the mechanisms underlying anticancer therapeutics
Medchemexpress LLC Phenol, 4-(di-1H-indol-3-ylmethyl)- | 151358-47-3 | 98.1% | 338.40 | 25 MG
DIM-C-pPhOH is a nuclear receptor 4A1 (NR4A1) antagonist. It inhibits cancer cell growth and mTOR signaling, and induces apoptosis and cellular stress. It reduces cell proliferation with IC50 values of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells.
- Nuclear receptor 4A1 (NR4A1) antagonist
- Inhibits cancer cell growth and mTOR signaling
- Induces apoptosis and cellular stress
- Reduces cell proliferation in ACHN and 786-O cells
- Inhibits NR4A1-regulated expression (survivin, bcl-2, EGFR)
- Induces sestrin 2, activates AMPKα, inhibits mTOR and downstream kinases
- Decreases β1-integrin protein, mRNA, and β1-integrin-dependent responses in MCF7, MDA-MB-231, and SKBR3 cells
- Inhibits migration of MDA-MB-231 and SKBR3 cells
- Significantly inhibits tumor growth in male athymic nude mice (ACHN cells)
eMolecules 6-CHLORO-1H-INDAZOL-4-AMINE | 885519-32-4 | MFCD07781370 | 1g
AstaTech | 6-CHLORO-1H-INDAZOL-4-AMINE | 1g | 412394803 | 76354 | 95.000 | 885519-32-4 | MFCD07781370 | 167.600 | C7H6ClN3
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Accela Chembio Inc 4-fluoro-1h-indazole | 1g | 341-23-1 | MFCD07371561 | 97+% | Shelf Life: 2160 Days | Light Sensitive/n2/+4
4-fluoro-1h-indazole | 1g | 341-23-1 | MFCD07371561 | 97+% | Shelf Life: 2160 Days | Light Sensitive/n2/+4