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Filtered Search Results
eMolecules 5-Bromo-2-phenylthiazole | 53715-67-6 | MFCD00561163 | 1g
Ambeed | 5-Bromo-2-phenylthiazole | 1g | 601095884 | A423722 | | 53715-67-6 | MFCD00561163 | 240.120 | C9H6BrNS
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BIOHIPPO scAAV-TH-NLS-Cre-WPREs
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Recombinant adeno associated virus expressing Cre under the TH promoter with WPRE and hGH polyA elements. The Cre dependent configuration enables expression only after recombination, providing precise targeted control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC M-isobutyl ibuprofen | 66622-47-7 | MFCD08275582 | >=98.0% | 206.28 g/mol | C13H18O2 | 5 MG
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m-Isobutyl Ibuprofen (Compound IMP-A) is an impurity produced during the synthesis of ibuprofen and is supplied as a research-grade impurity standard for analytical and quality-control applications. The material is intended for laboratory and research use only and should be handled according to the certificate of analysis and institutional safety procedures.
- Reference impurity for analytical and quality-control use.
- Intended for research use only, not for human or veterinary use.
- Available in small milligram pack sizes suitable for method development.
- Molecular formula C13H18O2; molecular weight 206.28 g/mol.
- Storage conditions provided in the certificate of analysis; follow laboratory safety guidance.
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eMolecules ChemScene / 1-(3-Bromoisoxazol-5-yl)ethanone / 100mg / 795362638 / CS-0436819 / 0.000 / 76596-53-7 / MFCD18801045 / 189.996 / C5H4BrNO2
ChemScene / 1-(3-Bromoisoxazol-5-yl)ethanone / 100mg / 795362638 / CS-0436819 / 0.000 / 76596-53-7 / MFCD18801045 / 189.996 / C5H4BrNO2
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TARGETMOL CHEMICALS INC S-methyl-KE-298 1MG
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Also available in 5 mg, 10 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes.S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells. Purity 96.9%
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Medchemexpress LLC Th-6 | 3031349-25-1 | 95.0% | 429.44 | 1 ML
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TH-6 is a potent HDAC inhibitor with IC50s of 0.115, 0.135, 0.242, 0.138, and 2.120 μM for HDAC1, HDAC2, HDAC3, HDAC6, and HDAC8, respectively. It demonstrates anti-tumor activity and inhibits cell migration and invasion, inducing apoptosis and cell cycle arrest at the G2/M phase.
- Inhibits cell migration and invasion
- Induces apoptosis
- Causes cell cycle arrest at the G2/M phase
- Demonstrates anti-tumor activity
- Potent HDAC inhibitor
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Medchemexpress LLC OF-02 | 1883431-67-1 | ≥98.0% | C84H152N4O6 | 25 MG
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OF-02 is an ionizable lipid essential for mRNA delivery, serving as a key component of lipid nanoparticles (LNPs). It becomes protonated in acidic endosomal environments, which aids in the escape of mRNA and effective protein expression in target cells. The lipid's pH-responsive membrane fusion properties allow it to complex with mRNA, disrupt endosomal membrane structures, and facilitate mRNA release into the cytoplasm.
- Ionizable lipid for mRNA delivery
- Key component of lipid nanoparticles (LNPs)
- Promotes endosomal escape of mRNA
- Induces protein expression in target cells
- Utilizes pH-responsive membrane fusion properties
- Enables mRNA release into the cytoplasm
- Used in mRNA vaccine development
- Used in gene editing applications
- Used in protein replacement therapy
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BIOHIPPO AAV-TH-fDIO-hChR2(H134R)-mCherry-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing hChR2(H134R) fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Cre and Flp logic configuration enables expression only after recombination, providing precise optogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC (S,R,S)-AHPC-C10-NHBoc | 2412055-13-9 | 713.97 g·mol⁻¹ | C38H59N5O6S | 10 MG
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(S,R,S)-AHPC-C10-NHBoc is a synthesized E3 ligase ligand-linker conjugate that couples the (S,R,S)-AHPC VHL ligand to a 10-carbon alkyl linker. It is designed for use as the VHL-recruiting element in BET-targeted PROTAC design and for studies involving E3 ligase ligand conjugation.
- Provides a VHL-based E3 ligase recruiting moiety for PROTAC development.
- Contains a 10-carbon alkyl linker to provide spacer flexibility between ligand and target binder.
- Designed for chemical synthesis and linker conjugation chemistry.
- Characterized by molecular formula C38H59N5O6S and molar mass 713.97 g·mol⁻¹.
- Store sealed away from moisture and light; in solvent: -80°C up to 6 months, -20°C up to 1 month.
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Medchemexpress LLC BAY-298 | 2471978-97-7 | 99.9% | 10 MM * 1 ML
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BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist. It demonstrates potent activity against human, rat, and cynomolgus monkey LH receptors, effectively reducing sex hormone levels. It is supplied as a 10 MM solution in DMSO.
- Orally active and selective LH-R antagonist
- Reduces sex hormone levels
- Potent inhibitory activity against human, rat, and cynomolgus monkey LH receptors
- Inhibits human ERG in HEK293 cells
- Lowers serum estradiol levels in proestrus female rats
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Medchemexpress LLC Met kinase-IN-2 | 2101241-90-9 | 98.4% | 562.59 g/mol | C33H27FN4O4 | 5 MG
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MET kinase-IN-2 is a potent, selective MET (c-Met/HGFR) kinase inhibitor with an enzymatic IC50 of 7.4 nM. The compound shows cellular growth inhibition across multiple cancer cell lines and demonstrates oral antitumor efficacy in xenograft models. It is supplied for preclinical research and is well characterized for purity and molecular properties.
- Potent MET kinase inhibition (IC50 7.4 nM).
- Selective profile with additional activity against AXL, Flt4, KDR, Mer, TEK, and TYRO3.
- Orally bioavailable with demonstrated in vivo antitumor efficacy.
- Documented cellular activity in multiple cancer cell lines.
- High purity and characterized molecular weight and formula.
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Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 | C24H16ClN3O2S | 5 MG
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A small-molecule inhibitor of DNA polymerase eta (Pol η) supplied for research use. Provided as a solid in milligram quantities for in vitro and preclinical studies, it is suitable for mechanism-of-action experiments and combination cytotoxicity assays.
- High purity: 98.0%.
- Molecular weight 445.92.
- Chemical formula C24H16ClN3O2S.
- Provided in a 5 MG vial suitable for laboratory assays.
- Intended for in vitro pharmacology and mechanism-of-action studies.
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Medchemexpress LLC (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone | 141645-16-1 | 99.6% | C19H17NO5 | 50 G
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This chemical is a drug intermediate utilized in the synthesis of various active compounds. It is intended for research purposes only and not for patient use.
- Drug intermediate
- Solid appearance
- Off-white to yellow color
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Sigma Aldrich Fine Chemicals Biosciences Thiazolyl Blue Tetrazolium Bromide | 298-93-1 | MFCD00011964 | 500mg
Thiazolyl Blue Tetrazolium Bromide | Purity: 98% | MW: 414.32 | 298-93-1 | MFCD00011964 | 500mg
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Medchemexpress LLC Phospho-Met (c-Met) (Tyr1349) Antibody (YA213) | 10 UL
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Phospho-Met c-Met (Tyr1349) Antibody (YA213) is a rabbit-derived, non-conjugated IgG monoclonal antibody specifically targeting Phospho-Met c-Met at the Tyr1349 residue. This antibody is supplied as a liquid in a formulation containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.05% BSA, and 0.01% Sodium azide as a preservative. It is suitable for various applications including Western Blot (WB) and Immunoprecipitation (IP).
- Specific for Phospho-Met c-Met (Tyr1349)
- Rabbit-derived IgG monoclonal antibody
- Non-conjugated for flexible experimental design
- Suitable for Western Blot (WB) and Immunoprecipitation (IP) applications
- Shipped with blue ice to maintain stability
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