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Filtered Search Results
Aobchem AOBCHEM
5000862639 1- 2 3-DIFLUOROPHENYL -2 2 2-T
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Apexbio Technology LLC Cytochrome c fragment (93-108) 5mg
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Cytochrome c fragment 93-108 is a peptide derived from cytochrome c a mitochondrial protein involved in apoptosis It is designed to interact with apoptotic protease activating factor-1 (Apaf-1) thereby promoting the assembly of the Apaf-1/caspase-9 apoptosome complex and regulating the caspase activation pathway Cytochrome c fragment 93-108 exerts its biological activity primarily through activation of the caspase cascade specifically the activation of caspase-9 and subsequent caspase-3 Based on these pharmacological properties cytochrome c fragment 93-108 holds research potential in studies of apoptosis-related signaling networks caspase activation pathways and drug screening targeting apoptosis regulators
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Aobchem AOBCHEM
5000862788 1- 2 3-DIFLUOROPHENYL -2 2 2-T
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eMolecules 142266-62-4 | 2,5,6-TRICHLORONICOTINAMIDE | AstaTech | MFCD22493418 | 225.450 | C6H3Cl3N2O | 95.000 | NC(=O)c1cc(Cl)c(Cl)nc1Cl | 0.25g | 347152262
2,5,6-TRICHLORONICOTINAMIDE | AstaTech | 142266-62-4 | MFCD22493418 | 225.450 | C6H3Cl3N2O | 95.000 | NC(=O)c1cc(Cl)c(Cl)nc1Cl | 0.25g | 347152262
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Medchemexpress LLC JH-VIII-157-02 | 1639422-97-1 | 99.0% | 465.55 | 100 MG
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JH-VIII-157-02 is a structural analogue of alectinib, functioning as an ALK inhibitor. It exhibits an IC50 of 2 nM for EML4-ALK G1202R in cells and potently inhibits various other EML4-ALK mutants and wild type (e.g., EML4-ALKwt, EAC1156Y, EAF1174L, EAS1206Y with IC50s of 2-196 nM). It shows selectivity at other kinases like IRAK1, CLK4, RET, and IRAK 4. JH-VIII-157-02 demonstrates inhibitory growth against cancer cell lines like H3122 and DFCI76 (EC50s of 5 nM and 19 nM). It also has good oral bioavailability and penetrates the CNS in mice.
- Structural analogue of alectinib
- Acts as an ALK inhibitor
- Shows potent inhibition of EML4-ALK G1202R mutant (IC50 of 2 nM)
- Potently inhibits other EML4-ALK mutants and wild type
- Exhibits selectivity at several other kinases
- Inhibits growth of cancer cell lines
- Good oral bioavailability in mice
- Penetrates the CNS of mice
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BIOHIPPO
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5000860775 HUMAN MET/C-MET/HGFR PAB
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eMolecules 2 4-DIBROMOTHIAZOLE 5G
5000161283 2 4-DIBROMOTHIAZOLE 5G
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![eMolecules 324017-23-4 | 4-[(Aminocarbonyl)amino]-N-Fmoc-L-phenylalanine | Acrotein ChemBio Inc. | MFCD30475861 | 445.475 | C25H23N3O5 | 97.000 | NC(=O)Nc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1 | 0.25g | 850145292](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000215976.jpg-250.jpg)
eMolecules 324017-23-4 | 4-[(Aminocarbonyl)amino]-N-Fmoc-L-phenylalanine | Acrotein ChemBio Inc. | MFCD30475861 | 445.475 | C25H23N3O5 | 97.000 | NC(=O)Nc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1 | 0.25g | 850145292
4-[(Aminocarbonyl)amino]-N-Fmoc-L-phenylalanine | Acrotein ChemBio Inc. | 324017-23-4 | MFCD30475861 | 445.475 | C25H23N3O5 | 97.000 | NC(=O)Nc1ccc(C[C@H](NC(=O)OCC2c3ccccc3-c3ccccc23)C(O)=O)cc1 | 0.25g | 850145292
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![Medchemexpress LLC (3-chloro-4-methylphenyl)-[4-(4-nitrophenyl)piperazin-1-yl]methanone | 431996-53-1 | MFCD03058358 | 99.3% | 359.81 g/mol | C18H18ClN3O3 | 100MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000237356.png-250.jpg)
Medchemexpress LLC (3-chloro-4-methylphenyl)-[4-(4-nitrophenyl)piperazin-1-yl]methanone | 431996-53-1 | MFCD03058358 | 99.3% | 359.81 g/mol | C18H18ClN3O3 | 100MG
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Filastatin is a small-molecule antifungal research reagent that inhibits Candida albicans filamentation and adhesion. It blocks the yeast-to-hyphal morphological transition and reduces fungal attachment to abiotic and human surfaces, showing activity at low micromolar concentrations.
- Inhibits Candida albicans filamentation.
- Reduces fungal adhesion to polystyrene and human cells.
- Active at low micromolar concentrations (IC50 ~3 μM).
- High reported purity suitable for research applications (≈99.3%).
- Available in multiple pack sizes for experimental flexibility.
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Medchemexpress LLC 2,4-Dimethylthiazole-5-carboxylic acid | 53137-27-2 | MFCD00052943 | 157.19 | 500 MG
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2,4-Dimethylthiazole-5-carboxylic acid is a versatile building block utilized in chemical synthesis, particularly for drug discovery and the development of pharmaceuticals and agrochemicals. Its unique thiazole structure imparts significant functionality, enabling the modification of lead compounds and the enhancement of biological activity. It is suitable for research use only.
- Used as a heterocyclic building block
- Enhances biological activity in compounds
- Important in pharmaceutical and agrochemical synthesis
- Applicable in the flavoring and fragrance industries
- Contributes to advancements in medicinal chemistry and agricultural science
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eMolecules 3-FLUOROBICYCLO 1.1.1 PE 0.25G
5000163602 3-FLUOROBICYCLO 1.1.1 PE 0.25G
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Aobchem AOBCHEM
5000873027 1- 2 5-DIFLUOROPHENYL -2 2-DIF
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Aobchem AOBCHEM
5000873037 ETHYL 2- 2-METHOXY-4- METHYLTH
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Aobchem AOBCHEM
5000873083 1- 4 5-DIMETHYL-2-THIAZOLYL -1
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Aobchem AOBCHEM
5000873188 1- 2- METHYLTHIO THIAZOL-5-YL
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