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Filtered Search Results
Aobchem AOBCHEM
5000916128 1- 2 6-DIFLUOROPYRIDIN-3-YL PR
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Aobchem AOBCHEM
5000940837 METHYL 2- 2-FLUORO-3- METHYLTH
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(C)OCCI | 1g | 449720363](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170842.jpg-250.jpg)
eMolecules 101166-65-8 | TERT-BUTYL(2-IODOETHOXY)DIMETHYLSILANE | AstaTech | MFCD09909940 | 286.228 | C8H19IOSi | 95.000 | CC(C)(C)[Si](C)(C)OCCI | 1g | 449720363
TERT-BUTYL(2-IODOETHOXY)DIMETHYLSILANE | AstaTech | 101166-65-8 | MFCD09909940 | 286.228 | C8H19IOSi | 95.000 | CC(C)(C)[Si](C)(C)OCCI | 1g | 449720363
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eMolecules 2-BROMONAPHTHALEN-1-AMIN 100MG
5000191475 2-BROMONAPHTHALEN-1-AMIN 100MG
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eMolecules 2-BROMONAPHTHALEN-1-AMINE 50MG
5000191474 2-BROMONAPHTHALEN-1-AMINE 50MG
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eMolecules IMINOMETHYLPHENYL-L6 500MG
5000191534 IMINOMETHYLPHENYL-L6 500MG
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Medchemexpress LLC TH-Z145 | 2260887-57-6 | C16H28O7P2 | 25 MG
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TH-Z145 is a lipophilic bisphosphonate that functions as an FPPS inhibitor with an IC50 of 210 nM. It has shown promising effects in preclinical studies, including strong prophylactic effects in pathogenic influenza models and inhibition of tumor growth in xenograft mouse models.
- Exhibits strong prophylactic effects in pathogenic influenza models
- Inhibits tumor growth and prolongs survival in B16-OVA xenograft mouse models
- Functions as an FPPS inhibitor with an IC50 of 210 nM
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL
- Not classified as a hazardous substance or mixture
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eMolecules 166525-49-1 | 1-(4,6-Dichloro-3-pyridyl)propan-1-one | ChemScene204.050 | C8H7Cl2NO | 98.000 | CCC(=O)c1cnc(Cl)cc1Cl | 100mg | 801481345
1-(4,6-Dichloro-3-pyridyl)propan-1-one | ChemScene | 166525-49-1204.050 | C8H7Cl2NO | 98.000 | CCC(=O)c1cnc(Cl)cc1Cl | 100mg | 801481345
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Selleck Chemical LLC GGTI 298 TFA salt
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GGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in the G1 phase of the cell cycle and induce apoptosis
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Medchemexpress LLC TH-237A | 1 ML
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TH-237A | 1 ML
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Medchemexpress LLC FAM49B (190-198) mouse | 1588388-60-6 | 1042.20 | 10 MG
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FAM49B (190-198) mouse is a peptide fragment of FAM49B. FAM49B is a mitochondria-localized protein that regulates mitochondrial fission, function and integrity, and tumor progression. It also acts as a negative regulator in T cell activation by repressing GTPase Rac activity and modulating cytoskeleton reorganization.
- Regulates mitochondrial fission
- Involved in mitochondrial function and integrity
- Contributes to tumor progression
- Acts as a negative regulator in T cell activation
- Represses GTPase Rac activity
- Modulates cytoskeleton reorganization
- Soluble in DMSO at 50 mg/mL
- Store as powder at -80°C for 2 years or -20°C for 1 year in sealed, moisture-free conditions
- Store in solvent at -80°C for 6 months or -20°C for 1 month in sealed, moisture-free conditions
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Medchemexpress LLC ENDO S2 S. PYOGENES 10UG
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5000194766 ENDO S2 S. PYOGENES 10UG
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Apexbio Technology LLC TH-302 918633-87-1 200mg
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TH-302 (CAS 918633-87-1) is a hypoxia-activated prodrug comprising a 2-nitroimidazole moiety linked to a brominated isophosphoramide mustard Under severe hypoxic conditions (approximately 0 1% O ) TH-302 undergoes bioreductive activation releasing the cytotoxic alkylating agent Br-IPM selectively within hypoxic tumor microenvironments In vitro studies demonstrate markedly increased cytotoxicity against tumor cell lines under hypoxia with IC50 values ranging from 0 1 to 0 8 M for H460 Caki-1 SK-MEL-5 DU145 and HCT116 cells while IC50 values exceed 40 M in normoxic conditions In H460 xenograft mouse models TH-302 induces dose-dependent tumor growth inhibition without hematological toxicity and increases H2AX-positive cells indicating DNA damage TH-302 is utilized to investigate tumor hypoxia-targeting therapies and mechanisms of selective cytotoxicity
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eMolecules 42014-51-7 | 2,5-dioxopyrrolidin-1-yl 2-bromoacetate | Absolute Chiral | MFCD00058571 | 236.021 | C6H6BrNO4 | 95.000 | BrCC(=O)ON1C(=O)CCC1=O | 1g | 345476321
2,5-dioxopyrrolidin-1-yl 2-bromoacetate | Absolute Chiral | 42014-51-7 | MFCD00058571 | 236.021 | C6H6BrNO4 | 95.000 | BrCC(=O)ON1C(=O)CCC1=O | 1g | 345476321
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(C)OCCBr | 1g | 459636791](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000165670.jpg-250.jpg)
eMolecules 86864-60-0 | (2-Bromoethoxy)(tert-butyl)dimethylsilane | Synthonix - Stock | MFCD00209550 | 239.228 | C8H19BrOSi | 96.000 | CC(C)(C)[Si](C)(C)OCCBr | 1g | 459636791
(2-Bromoethoxy)(tert-butyl)dimethylsilane | Synthonix - Stock | 86864-60-0 | MFCD00209550 | 239.228 | C8H19BrOSi | 96.000 | CC(C)(C)[Si](C)(C)OCCBr | 1g | 459636791
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