Thiazoles

Organic heterocyclic compounds that consist of an azole with both sulfur and nitrogen atoms; includes compounds that are derived from thiazoles.

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931 – 945 of 1,953 results

931

Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 25 MG

Anticancer agent 93 is a 4-Hydroxycoumarin derivative. It can inhibit invasion and migration of lung cancer cells by modulating the expression of epithelial-mesenchymal transition (EMT) effectors.

4-Hydroxycoumarin derivative
Inhibits invasion and migration of lung cancer cells
Modulates expression of epithelial-mesenchymal transition (EMT) effectors
Purity of 98.01%
White to off-white solid appearance
Inhibits A549 cell invasion by approximately 50% at concentrations of 5-15 μM for 24 hours
Significantly inhibits A549 cell migration at 15 μM for 24-72 hours
Inhibits lung cancer cell motility by downregulating EMT markers at 5-15 μM for 4 hours
Decreases expression of N-cadherin and E-cadherin in A549 cells

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932

BIOHIPPO AAV-TH-hM4D(Gi)-mCherry-WPRE-hGH-polyA

Recombinant adeno associated virus expressing hM4D(Gi) fused to mCherry under the TH promoter with WPRE and hGH polyA elements. The Dre dependent configuration enables expression only after recombination, providing precise chemogenetic control of targeted neurons. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.

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933

Medchemexpress LLC TERT activator-1 | 666699-46-3 | 99.5% | 331.77 | 50 MG

TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). It promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. It offers several benefits:

Promotes adult neurogenesis.
Enhances neuromuscular function.
Reduces cellular senescence and systemic inflammation in aged mice.
Can be used in the study of aging.

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934

Medchemexpress LLC Di(adamantan-1-yl)phosphine | 131211-27-3 | 97.0% | 302.43 | 5 G

Di(adamantan-1-yl)phosphine is a biological molecule intended for research use only and not sold to patients. It appears as a white to off-white solid.

Store at 4°C, protected from light, and under nitrogen
When in solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen

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935

Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 100 MG

Anticancer agent 93 is a 4-Hydroxycoumarin derivative that demonstrates efficacy against lung cancer cells. It inhibits invasion and migration by modulating epithelial-mesenchymal transition (EMT) effectors, making it a potential candidate for cancer research.

Inhibits A549 cell invasion by approximately 50%
Significantly inhibits A549 cell migration
Decreases lung cancer cell motility by downregulating EMT markers
Reduces expression of N-cadherin and E-cadherin in A549 cells

Pricing & Availability

936

Medchemexpress LLC 2 4-Dimethylthiazole | 10G

2 4-Dimethylthiazole | 10G

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937

Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 g·mol⁻¹ | C24H16ClN3O2S | 25 MG

PNR-7-02 is a small-molecule inhibitor of DNA polymerase eta (Pol η) used in research on translesion synthesis and polymerase-mediated drug resistance. It is an indole thio-barbituric acid derivative reported to inhibit Pol η (IC50 ≈ 8 μM) and to act synergistically with cisplatin in cancer cell lines.

Inhibits Pol η with reported IC50 ≈ 8 μM
Also shows activity against hRev1 and hpol λ
High purity (98.0%) suitable for biochemical assays
Available as a 25 MG package, other sizes available
Indole thio-barbituric acid scaffold, useful as a small-molecule probe
For research use only; not for human or clinical use

Pricing & Availability

938

Medchemexpress LLC 1,2:5,6-Bis-O-(1-methylethylidene)-α-D-allofuranose | 2595-05-3 | 260.29 | 100 G

1,2:5,6-Bis-O-(1-methylethylidene)-α-D-allofuranose is a biochemical reagent used in glycobiology research. This field investigates the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the role of glycans in biological systems. It is closely related to basic research, biomedicine, and biotechnology.

White to off-white solid
Purity of ≥98.0% (NMR)
¹H NMR spectrum consistent with structure
Used in glycobiology research
Supports studies in carbohydrate chemistry and glycan enzymology
Aids in protein-glycan recognition research

Pricing & Availability

939

eMolecules 1-TERT-BUTOXYCARBONYLPIPERI 1G

5000158372 1-TERT-BUTOXYCARBONYLPIPERI 1G

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940

eMolecules 2-TERT-BUTOXYCARBONYLAMI 5G

5000158375 2-TERT-BUTOXYCARBONYLAMI 5G

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941

eMolecules 3 5-DIFLUOROPYRIDIN-2-YL 25G

5000158965 3 5-DIFLUOROPYRIDIN-2-YL 25G

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942

eMolecules 2-DI-TERT-BUTYLPHOSPHINOB 5G

5000162544 2-DI-TERT-BUTYLPHOSPHINOB 5G

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943

eMolecules 1- TERT-BUTOXYCARBONYLAMI 5G

5000162829 1- TERT-BUTOXYCARBONYLAMI 5G

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944

eMolecules THIAZOL-5-YLMETHYL N- 1S 2 1G

5000164611 THIAZOL-5-YLMETHYL N- 1S 2 1G

Pricing & Availability

945

eMolecules THIAZOL-5-YLMETHYL N- 1S 2 5G

5000164667 THIAZOL-5-YLMETHYL N- 1S 2 5G

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Thiazoles

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Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

BIOHIPPO AAV-TH-hM4D(Gi)-mCherry-WPRE-hGH-polyA Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TERT activator-1 | 666699-46-3 | 99.5% | 331.77 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Di(adamantan-1-yl)phosphine | 131211-27-3 | 97.0% | 302.43 | 5 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 3-Chloro-N-(4-hydroxy-2-oxo-2H-chromen-3-yl)benzamide | 94205-22-8 | C16H10ClNO4 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2 4-Dimethylthiazole | 10G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 g·mol⁻¹ | C24H16ClN3O2S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1,2:5,6-Bis-O-(1-methylethylidene)-α-D-allofuranose | 2595-05-3 | 260.29 | 100 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More