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Filtered Search Results
BIOHIPPO AAV-TH-GCaMP6f-WPRE-hGH-polyA
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Recombinant adeno associated virus expressing GCaMP6f under the TH promoter with WPRE and hGH polyA elements. Offered under the Biohippo AAVX Series with multiple serotypes available including AAV2/1, AAV2/2, AAV2/5, AAV2/6, AAV2/6m, AAV2/6.2FF, AAV2/7m8, AAV2/8, AAV2/9, AAV2/DJ, AAV2/DJ8, AAV2/Retro, AAV2/PHP.eB, AAV2/PHP.B, AAV2/rh10, AAV2/PHP.S, AAV2/anc80, AAV2/B10, AAV2/olig001, AAV2/BI30, AAV2/BR1, AAV2/MG1.2, AAV1/2, AAV2/MaCPNS1, and AAV2/MaCPNS2. Regular titer is greater than or equal to 2.00E+12 vg per mL, with high titer greater than or equal to 1.00E+13 vg per mL available upon request at no additional cost. Customers may specify preferred serotype and titer when placing orders.
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Medchemexpress LLC Phospho-ERK1 + 2 (Thr183/Tyr185) Antibody | 10 UL
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Phospho-ERK1 + 2 (Thr183/Tyr185) Antibody is a rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to phospho-ERK1 + 2 (Thr183/Tyr185). It is for research use only. The antibody recognizes human and mouse species, with predicted reactivity in rat, chicken, dog, cow, horse, rabbit, and guinea pig.
- Host: Rabbit
- Clonality: Polyclonal
- Sensitivity: Endogenous
- Conjugation: Non-conjugated
- Modification: Phosphorylated
- Isotype: IgG
- Appearance: Liquid
- Formulation: Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- Storage and stability: Stored at -20°C for 1 year. Avoid repeated freeze/thaw cycles
- Shipping: With blue ice
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Apexbio Technology LLC YL-109 36341-25-0 10mM (in 1mL DMSO)
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YL-109 (CAS 36341-25-0) is a small molecule with demonstrated antitumor properties primarily acting through modulation of the aryl hydrocarbon receptor (AhR) signaling pathway This compound enhances expression of the molecular chaperone-associated ubiquitin ligase CHIP (C-terminus of Hsp70-interacting protein) leading to downstream regulation of processes implicated in cell proliferation and invasion In breast cancer models YL-109 induces CHIP expression resulting in suppressed proliferation and invasive capabilities of cancer cells YL-109 is thus a valuable tool for investigating AhR-mediated anticancer mechanisms and exploring therapeutic strategies in breast cancer research
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Medchemexpress LLC N-[5-[4-chloro-3-(2-hydroxyethylsulfamoyl)phenyl]-4-methyl-1,3-thiazol-2-yl]acetamide | 593960-11-3 | >98.0% | 100 MG
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PIK-93 is a small-molecule kinase inhibitor used in research to inhibit PI4KIIIβ and certain PI3K isoforms. It is reported to inhibit PI4KIIIβ with an IC50 of 19 nM, PI3Kγ with an IC50 of 16 nM, and PI3Kα with an IC50 of 39 nM.
- Potent PI4KIIIβ inhibitor; IC50 = 19 nM.
- Also inhibits PI3Kγ (IC50 = 16 nM) and PI3Kα (IC50 = 39 nM).
- Chemical formula C14H16ClN3O4S2; molecular weight 389.9 g/mol.
- Typically supplied as a solid for research applications.
- Purity commonly reported ≥98% by suppliers.
- Useful for studies of PI4K/PI3K signaling and viral replication pathways.
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Medchemexpress LLC α-Methyltyrosine methyl ester hydrochloride | 7361-31-1 | MFCD00012606 | 98.9% | 245.71 | 5 G
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α-Methyltyrosine methyl ester hydrochloride is an orally active and competitive tyrosine hydroxylase inhibitor. It can inhibit the conversion of tyrosine to dopamine. It causes kidney damage and urethral calculi in rats and can be used as a tool for sympathetic nervous system research.
- Orally active
- Competitive tyrosine hydroxylase inhibitor
- Inhibits the conversion of tyrosine to dopamine
- Can be used as a tool for sympathetic nervous system research
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Medchemexpress LLC MET kinase-IN-4 | 888719-03-7 | 99.0% | 458.42 | 50 MG
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MET kinase-IN-4 is an orally active Met kinase inhibitor with potent Met kinase inhibitory activity (IC50 = 1.9 nM). It also inhibits Flt-3 and VEGFR-2 kinases. This compound shows good metabolic stability and can be used for cancer research. It exhibits a favorable pharmacokinetic profile in mice and demonstrates significant antitumor activity in the GTL-16 human gastric carcinoma xenograft model.
- Orally active Met kinase inhibitor
- Potent Met kinase inhibitory activity (IC50 = 1.9 nM)
- Inhibits Flt-3 and VEGFR-2 kinases
- Good metabolic stability in human and mouse liver microsomes
- Suitable for cancer research
- Exhibits favorable pharmacokinetic profile in mice
- Demonstrates significant antitumor activity in GTL-16 human gastric carcinoma xenograft model
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Aobchem 1-(5-Chloro-2 4-difluorophenyl)ethanone | ≥97% | CAS 1638980-49-0 | C8H5ClF2O | 250mg
1-(5-Chloro-2 4-difluorophenyl)ethanone | ≥97% | CAS 1638980-49-0 | C8H5ClF2O | 250mg
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Aobchem 1-(4-Chloro-2 6-difluorophenyl)ethanol | ≥97% | CAS 1780642-82-1 | C8H7ClF2O | 250mg
1-(4-Chloro-2 6-difluorophenyl)ethanol | ≥97% | CAS 1780642-82-1 | C8H7ClF2O | 250mg
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Aobchem AOBCHEM
5001037903 2-MORPHOLINOPYRIDIN-4-YL BORO
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Aobchem AOBCHEM
5001045724 5-BROMOTHIEN-2-YL METHANOL 10
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Medchemexpress LLC PNR-7-02 | 1633660-76-0 | 98.0% | 445.92 g·mol⁻¹ | C24H16ClN3O2S | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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PNR-7-02 is a small-molecule inhibitor of DNA polymerase eta (Pol η) used in research on translesion synthesis and polymerase-mediated drug resistance. It is an indole thio-barbituric acid derivative reported to inhibit Pol η (IC50 ≈ 8 μM) and to act synergistically with cisplatin in cancer cell lines.
- Inhibits Pol η with reported IC50 ≈ 8 μM
- Also shows activity against hRev1 and hpol λ
- High purity (98.0%) suitable for biochemical assays
- Available as a 25 MG package, other sizes available
- Indole thio-barbituric acid scaffold, useful as a small-molecule probe
- For research use only; not for human or clinical use
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eMolecules 5694-68-8 | 1,3-Dioxolane-2-methanol | Accela ChemBio | MFCD08062572 | 104.105 | C4H8O3 | 97.000 | OCC1OCCO1 | 0.25g | 789348258
1,3-Dioxolane-2-methanol | Accela ChemBio | 5694-68-8 | MFCD08062572 | 104.105 | C4H8O3 | 97.000 | OCC1OCCO1 | 0.25g | 789348258
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eMolecules 64987-85-5 | (2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarboxylate | Synthonix | MFCD00009634 | 334.328 | C16H18N2O6 | 97.000 | O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1 | 5g | 808570424
(2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarboxylate | Synthonix | 64987-85-5 | MFCD00009634 | 334.328 | C16H18N2O6 | 97.000 | O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1 | 5g | 808570424
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eMolecules 64987-85-5 | (2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarboxylate | Synthonix | MFCD00009634 | 334.328 | C16H18N2O6 | 97.000 | O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1 | 10g | 808570425
(2,5-dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarboxylate | Synthonix | 64987-85-5 | MFCD00009634 | 334.328 | C16H18N2O6 | 97.000 | O=C(ON1C(=O)CCC1=O)C1CCC(CN2C(=O)C=CC2=O)CC1 | 10g | 808570425
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eMolecules 95408-45-0 | 1,1'-Bis(di-tert-butylphosphino)ferrocene Palladium Dichloride | Accela ChemBio | MFCD08064219 | 651.750 | C26H44Cl2FeP2Pd | 98.000 | [Cl-].[Cl-].[Fe].[Pd++].CC(C)(C)P(c1cccc1)C(C)(C)C.CC(C)(C)P(c1cccc1)C(C)(C)C | 0.1g | 783627424
1,1'-Bis(di-tert-butylphosphino)ferrocene Palladium Dichloride | Accela ChemBio | 95408-45-0 | MFCD08064219 | 651.750 | C26H44Cl2FeP2Pd | 98.000 | [Cl-].[Cl-].[Fe].[Pd++].CC(C)(C)P(c1cccc1)C(C)(C)C.CC(C)(C)P(c1cccc1)C(C)(C)C | 0.1g | 783627424
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