Wheaton glass containers are the choice for lyophilization. They excel in the three majors factors that contribute to successful Lyophillization: heat transfer, sealability, & water vapor transmission barrier. Heat Transfer–a Wheaton Glass serum vial, as opposed to glass serum bottles, plastic serum bottles, & other containers has a very consistent thin wall & bottom that allows the heating phase of the lyophilization process to take place rapidly & effectively. Sealability–Wheaton glass serum vials feature a inblowbackin feature in neck & bottom that allows for a 2 or 3 legged lyophilization stopper to be securely & evenly seated in the mouth of the vial. Water vapor Transmission Barrier–Wheaton glass serum vials are made from premium, low extractable, borosilicate glass, which offers a superiorbarrier to water vapors. These vials can be autoclaved, by dry heat, by chemical, by gas, or by radiation.