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Abcam Nefazodone hydrochloride, 5-HT2A antagonist, 10MG
MW 506.5 Da, Purity >99%. Potent 5-HT2A receptor antagonist (Ki = 7.1 nM for inhibition of [3H] ketanserin binding in rat cortex). Additionally blocks α1 adrenoceptors (Ki values are 5.5 and 84 nM at α1 and α2, respectively). Acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) (Ki values are 220 and 555 nM at rat SERT and NET, respectively). Antidepressant.
The product is subject to the following: Abcam Restricted Use Statement
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