Protein Molecular Weight Markers
ABclonal Technology BCR Rabbit pAb
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The unregulated tyrosine kinase activity of BCR-ABL1 contributes to the immortality of leukaemic cells. The BCR protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac and other kinases. Two transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology SERPINF2 Rabbit pAb
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology WBP11 Rabbit pAb
This gene encodes a nuclear protein, which colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. This protein has 95% amino acid sequence identity to the mouse Wbp11 protein. It contains two proline-rich regions that bind to the WW domain of Npw38, a nuclear protein, and thus this protein is also called Npw38-binding protein NpwBP. The Npw38-NpwBP complex may function as a component of an mRNA factory in the nucleus.
ABclonal Technology NOS1 Rabbit pAb
The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5 UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
ABclonal Technology FAM107A Rabbit pAb
Predicted to enable actin binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle, negative regulation of focal adhesion assembly, and regulation of cytoskeleton organization. Located in several cellular components, including focal adhesion, ruffle membrane, and stress fiber.
ABclonal Technology MIEF1 Rabbit pAb
Enables ADP binding activity, GDP binding activity, and identical protein binding activity. Involved in several processes, including positive regulation of mitochondrial fission, positive regulation of mitochondrial translation, and positive regulation of protein targeting to membrane. Located in mitochondrial matrix and mitochondrial outer membrane. Colocalizes with mitochondrial large ribosomal subunit.
ABclonal Technology COMMD5 Rabbit pAb
Predicted to be involved in proximal tubule morphogenesis. Located in cytosol and nucleoplasm.
Proteintech Group Inc Prestained protein marker
The PL00001 Regular Range Protein Marker is a ready to use three-color protein standard with 10 prestained proteins covering a wide range of molecular weights from 10 to 180 kDa. The PL00001 Prestained Protein Marker is designed for monitoring protein separation during SDS-polyacrylamide gel electrophoresis, verification of Western transfer efficiency on membranes, (PVDF, nylon, or nitrocellulose) and for estimating the size of proteins.
ABclonal Technology ZNF296 Rabbit pAb
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and spermatogenesis. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus.
ABclonal Technology ZMAT2 Rabbit pAb
Predicted to enable DNA binding activity and zinc ion binding activity. Involved in mRNA splicing, via spliceosome. Located in nucleus. Part of U2-type precatalytic spliceosome.
Revvity Health Sciences Inc Protein Low Molecular Weight Assay Reagent Kit
Protein Low Molecular Weight Assay Reagent Kit
ABclonal Technology PDE7A Rabbit pAb
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
American Radiolabeled Chemicals Inc PROT MOL MARKER 14C 1UC
Protein molecular weight markers-14C 1uCi in 0.01M sodium phosphate (pH 7.2), 0.01 mCi/ml, S.A. 10-100 ug/mg, Mixture of Myosin-methyl-14C methylated, Phosphorylase B-methyl-14C methylated, BSA-methyl-14C methylated, Ovalbumin-methyl-14C methylated, Carbon