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Filtered Search Results
Medchemexpress LLC Aminooxy-PEG2-alcohol | 185022-12-2 | MFCD30182047 | 121.14 | C4H11NO3 | 100 MG
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Aminooxy-PEG2-alcohol is a short PEG-based linker containing an aminooxy functional group and a terminal hydroxyl. It is used as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and as a PEG-based linker in PROTAC synthesis.
- Non-cleavable PEG linker for ADC and PROTAC synthesis.
- Contains an aminooxy group for selective oxime ligation and bioconjugation.
- Molecular formula C4H11NO3; molecular weight 121.14.
- Available pack sizes: 100 MG, 250 MG, 1 G.
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eMolecules Ambeed / 6-(Benzyloxy)pyridin-3-ol / 1g / 490514998 / A153122 / / 725256-57-5 / MFCD06798281 / 201.225 / C12H11NO2
Ambeed / 6-(Benzyloxy)pyridin-3-ol / 1g / 490514998 / A153122 / / 725256-57-5 / MFCD06798281 / 201.225 / C12H11NO2
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Apexbio Technology LLC LXR-623 875787-07-8 100mg
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LXR-623 (CAS 875787-07-8) is a small-molecule partial agonist targeting liver X receptors LXR- and LXR- It selectively activates LXR- and LXR- modulating cholesterol homeostasis by regulating gene expression involved in cholesterol transport LXR-623 exerts its biological activity primarily through induction of cholesterol transporters such as ABCA1 and ABCG1 enhancing cholesterol efflux and reverse cholesterol transport In animal models oral administration of LXR-623 increases expression of ABCA1 and ABCG1 in peripheral blood cells and intestinal ABCG5/ABCG8 in mouse atherosclerosis models with reported IC50 values of 24 nM for LXR- and 179 nM for LXR- Based on these pharmacological properties LXR-623 holds research potential in atherosclerosis and Alzheimer s disease
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Ambeed N1 N2Bis 5methyl 1 1 biphenyl
N1,N2-Bis(5-methyl-[1,1'-biphenyl]-2-yl)oxalamide, 1809289-04-0, 98%
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Chem-Impex International, Inc. 2-Methoxybenzyl alcohol | 612-16-8 | MFCD00004611 | 1KG
2-Methoxybenzyl alcohol, 612-16-8, MFCD00004611, 1KG
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eMolecules 2-Fluoro-6-nitrobenzyl alcohol | 1643-60-3 | MFCD11110169 | 1g
Apollo Scientific | 2-Fluoro-6-nitrobenzyl alcohol | 1g | 562440929 | PC51079 | | 1643-60-3 | MFCD11110169 | 171.127 | C7H6FNO3
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Cayman Chemical 4-Hydroxybenzyl Alcohol 100g
An aglycone form of gastrodin; inhibits LPS-induced NO and ROS production and decreases iNOS levels in RAW 264.7 cells at 0.5 and 1 mM; reduces exudate volume and leukocyte infiltration in a rat model of carrageenan-induced air pouch inflammation at 1.5 and 4.5 mg/animal; inhibits acetic acid-induced writhing in mice at 50 and 100 mg/kg; reduces infarct volume and the number of TUNEL-positive neurons in the ipsilateral cortex in a rat model of focal cerebral ischemia induced by transient MCAO at 50 mg/kg; increases the number of entries into, and the percentage of time spent in, the open arms of the elevated plus maze in mice at 50 and 100 mg/kg
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Cayman Chemical 4-Hydroxybenzyl Alcohol 250g
An aglycone form of gastrodin; inhibits LPS-induced NO and ROS production and decreases iNOS levels in RAW 264.7 cells at 0.5 and 1 mM; reduces exudate volume and leukocyte infiltration in a rat model of carrageenan-induced air pouch inflammation at 1.5 and 4.5 mg/animal; inhibits acetic acid-induced writhing in mice at 50 and 100 mg/kg; reduces infarct volume and the number of TUNEL-positive neurons in the ipsilateral cortex in a rat model of focal cerebral ischemia induced by transient MCAO at 50 mg/kg; increases the number of entries into, and the percentage of time spent in, the open arms of the elevated plus maze in mice at 50 and 100 mg/kg
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Medchemexpress LLC Benzyl butyl phthalate | 85-68-7 | 97.0% | 312.36 | 10 MG
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Benzyl butyl phthalate (BBP) is a phthalic acid ester (PAE) that can trigger the migration and invasion of hemangioma (HA) cells by upregulating Zeb1. It also activates aryl hydrocarbon receptor (AhR) in breast cancer cells, stimulating SPHK1/S1P/S1PR3 signaling and enhancing the formation of metastasis-initiating breast cancer stem cells (BCSCs). BBP is commonly added during the manufacturing of plastics to increase flexibility and elasticity.
- Can trigger the migration and invasion of hemangioma (HA) cells via upregulation of Zeb1.
- Activates aryl hydrocarbon receptor (AhR) in breast cancer cells.
- Stimulates SPHK1/S1P/S1PR3 signaling.
- Enhances the formation of metastasis-initiating breast cancer stem cells (BCSCs).
- Induces histone modifications in S1PR3 in side population (SP) cells.
- Commonly added during plastic manufacturing to increase flexibility and elasticity.
- For research use only.
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Medchemexpress LLC Benzyl DC-81 (compound 6a) | 127810-79-1 | C20H20N2O3 | 25 MG
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Benzyl DC-81 (compound 6a) is an anticancer agent that exhibits antiproliferative activity against A375 and MCF-7 cells. It is categorized as an ADC Payload, falling under the Antibody-drug Conjugate/ADC Related pathway.
- Exhibits antiproliferative activity against A375 and MCF-7 cells
- Molecular weight is 336.38
- Targeted as an ADC payload
- Appearance as a light yellow to yellow solid
- Soluble in DMSO at 300 mg/mL (891.85 mM)
- Powder storage: -20°C for 3 years
- In solvent storage: -80°C for 6 months, -20°C for 1 month
- Purity (LCMS): 95.80%
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Medchemexpress LLC N-((Benzyloxy)carbonyl)-N-methyl-L-valine | 42417-65-2 | 99.46% | 265.30 | 5 G
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N-((Benzyloxy)carbonyl)-N-methyl-L-valine is a valine derivative. Amino acids and amino acid derivatives are commercially used as ergogenic supplements, influencing the secretion of anabolic hormones, supplying fuel during exercise, improving mental performance during stress-related tasks, and preventing exercise-induced muscle damage. They are recognized as beneficial ergogenic dietary substances.
- Appearance: Solid
- Color: White to off-white
- Storage powder: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
- Soluble in DMSO at 200 mg/mL (753.86 mM); requires ultrasonic assistance
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Medchemexpress LLC Benzyl butyl phthalate | 85-68-7 | 97.0% | 312.36 | 1 MG
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Benzyl butyl phthalate | 85-68-7 | 97.0% | 312.36 | 1 MG
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Medchemexpress LLC Benzyl-PEG2-azide | 1260001-87-3 | 99.1% | 100 MG
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Benzyl-PEG2-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its azide group, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, and strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Functions as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent with an azide group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Allows for strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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eMolecules ChemScene / 1-(234-Trifluorophenyl)ethanamine / 100mg / 632306221 / CS-0161975 / 0.000 / 780027-85-2 / MFCD17254431 / 175.154 / C8H8F3N
ChemScene / 1-(234-Trifluorophenyl)ethanamine / 100mg / 632306221 / CS-0161975 / 0.000 / 780027-85-2 / MFCD17254431 / 175.154 / C8H8F3N
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Medchemexpress LLC (S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride | 105590-97-4 | 329.82 | 10 G
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(S)-5-Benzyl 1-tert-butyl 2-aminopentanedioate hydrochloride is a glutamic acid derivative that appears as a white to off-white solid. It is intended for research use only. Amino acids and their derivatives, such as this compound, are recognized for their beneficial role as ergogenic dietary substances.
- Utilized as ergogenic supplements in commercial applications
- Influences anabolic hormone secretion
- Supplies fuel during exercise
- Improves mental performance under stress
- Helps prevent exercise-induced muscle damage
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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