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Filtered Search Results
Cayman Chemical 4-Hydroxybenzyl Alcohol 10g
An aglycone form of gastrodin; inhibits LPS-induced NO and ROS production and decreases iNOS levels in RAW 264.7 cells at 0.5 and 1 mM; reduces exudate volume and leukocyte infiltration in a rat model of carrageenan-induced air pouch inflammation at 1.5 and 4.5 mg/animal; inhibits acetic acid-induced writhing in mice at 50 and 100 mg/kg; reduces infarct volume and the number of TUNEL-positive neurons in the ipsilateral cortex in a rat model of focal cerebral ischemia induced by transient MCAO at 50 mg/kg; increases the number of entries into, and the percentage of time spent in, the open arms of the elevated plus maze in mice at 50 and 100 mg/kg
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Ambeed HPhe 4Ac OH
H-Phe(4-Ac)-OH, 122555-04-8, 97%
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Medchemexpress LLC M-PEG24-alcohol | 2376450-73-4 | 99.7% | C49H100O25 | 250 MG
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m-PEG24-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins by utilizing two ligands connected by this linker: one for an E3 ubiquitin ligase and the other for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates targeted protein degradation
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Medchemexpress LLC 3-chlorogentisyl alcohol | 32744-80-2 | 99.7% | 174.58 g/mol | C7H7ClO3 | 10 MG
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3-Chlorogentisyl alcohol is a small-molecule inhibitor of E. coli β-glucuronidase with reported antiproliferative activity. It is provided as a high-purity solid for biochemical and enzyme inhibition research.
- Potent E. coli β-glucuronidase inhibitor (IC50 0.74 μM; Ki 0.58 μM).
- Molecular formula C7H7ClO3; molecular weight 174.58 g/mol.
- Purity 99.7%.
- Available as solid quantities (including 10 mg) and as a 10 mM solution in DMSO.
- Appearance off-white to light yellow solid.
- Storage: powder -20°C; in solvent -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- | 957205-14-0 | 98.0% | C10H21BrO5 | 100 MG
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are composed of two distinct ligands connected by a linker, where one targets an E3 ubiquitin ligase and the other targets a specific protein. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective degradation of target proteins
- Utilizes the ubiquitin-proteasome system
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Medchemexpress LLC 3,6,9,12-Tetraoxatetradecan-1-ol, 14-bromo- | 957205-14-0 | 98.0% | C10H21BrO5 | 1 G
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Bromo-PEG5-alcohol is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. PROTACs work by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- PROTACs utilize the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Polyvinyl alcohol | 9002-89-5 | 88.7% | 85,000-124,000 | (C2H4O)x | 50g
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Polyvinyl alcohol (Mw 85000-124000 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 85000-124000 and hydrolytic properties The degree of hydrolysis refers to the degree to which the acetate groups in the original polyvinyl acetate are converted into hydroxyl groups during the hydrolysis process Polyvinyl alcohol (Mw 85000-124000 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate And polyvinyl alcohol is obtained A degree of hydrolysis of 87-89% indicates that a large part of the acetate groups have been removed resulting in a large number of hydroxyl groups in the PVA structure Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel which can be used as biological excipient[1]
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Medchemexpress LLC ALC-0315 | 2036272-55-4 | 99.4% | 766.27 | 1 G
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ALC-0315 is an ionisable aminolipid that facilitates mRNA compaction and aids in its cellular delivery and cytoplasmic release through suspected endosomal destabilization. It can be utilized to form lipid nanoparticle (LNP) delivery vehicles, which have been employed in the research of mRNA COVID-19 vaccines.
- Ionisable aminolipid
- Facilitates mRNA compaction
- Aids mRNA cellular delivery
- Supports cytoplasmic release via endosomal destabilization
- Forms lipid nanoparticle delivery vehicles
- Used in mRNA vaccine research
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Medchemexpress LLC p-Coumaryl alcohol | 3690-05-9 | MFCD00018809 | 1 MG
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p-Coumaryl alcohol is an antioxidant that can be isolated from Alpinia officinarum Hance. It exhibits an inhibitory effect during the autoxidation of methyl linoleate. This compound is a phenylpropanoid, acting as a crucial monolignol precursor in the biosynthesis of lignin, a complex organic polymer found in plant cell walls.
- Antioxidant properties.
- Isolated from Alpinia officinarum Hance.
- Inhibits autoxidation of methyl linoleate.
- Crucial monolignol precursor.
- Involved in lignin biosynthesis.
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Aobchem 4-Hydroxymethylphenylboronic acid, pinacol ester, AOBCHEM USA 18256-5G. 302348-51-2. MFCD09837617
4-Hydroxymethylphenylboronic acid, pinacol ester, AOBCHEM USA 18256-5G. 302348-51-2. MFCD09837617
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![eMolecules Broadpharm / DBCO-Val-Cit-PAB-MMAE / 10mg / 718091664 / BP-28214 / 95.000 / 2768446-73-5 / [null] / 1410.766 / C77H107N11O14](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502479553.JPG-250.jpg)
eMolecules Broadpharm / DBCO-Val-Cit-PAB-MMAE / 10mg / 718091664 / BP-28214 / 95.000 / 2768446-73-5 / [null] / 1410.766 / C77H107N11O14
Broadpharm / DBCO-Val-Cit-PAB-MMAE / 10mg / 718091664 / BP-28214 / 95.000 / 2768446-73-5 / [null] / 1410.766 / C77H107N11O14
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Sigma Aldrich Fine Chemicals Biosciences Heptyl alcohol >=97%, FCC, FG | 111-70-6 | MFCD00002986 |
Heptyl alcohol >=97%, FCC, FG | Purity: >=97% | Mol Wt: 116.2 | 111-70-6 | MFCD00002986 |
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Medchemexpress LLC Cetearyl alcohol | 67762-27-0 | MFCD01076350 | 99.1% | 512.93 g/mol | C34H72O2 | 250 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Cetearyl alcohol is a mixed fatty alcohol (cetyl and stearyl alcohols) used as a multifunctional excipient and cosmetic ingredient to soften, thicken, emulsify, and stabilize formulations. It is supplied as a white to off-white solid and is commonly used in topical and oral formulations for its emollient and texture-modifying properties.
- Acts as an emollient to soften and hydrate skin
- Functions as a thickener and viscosity modifier
- Serves as a nonionic emulsifier in many formulation types
- Improves formulation stability and sensory texture
- Compatible with common cosmetic and pharmaceutical ingredients
- Soluble in DMSO at approximately 25 mg/mL with sonication
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Ambeed Boc iodoAlaOMe
Boc-β-iodo-Ala-OMe, 93267-04-0, 98%
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Medchemexpress LLC S-(4-Hydroxybenzyl)glutathione | 129636-38-0 | 10 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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S-(4-Hydroxybenzyl)glutathione is a glutathione derivative. It has been shown to inhibit the in vitro binding of kainic acid to brain glutamate receptors, with an IC50 of 2 μM.
- It is a glutathione derivative.
- It inhibits the in vitro binding of kainic acid to brain glutamate receptors.
- It has an IC50 of 2 μM for inhibiting kainic acid binding.
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