Cryostats and Accessories

Instruments used to cut histology slides and/or maintain low temperatures of samples or devices mounted within them. Products also include cryostat accessories and replacement parts such as specimen chucks, freezing sprays, and blade carriers.

Cryostats are typically located in the surgical area of a healthcare facility to allow for immediate examination of tissue pathology, usually during surgical procedures. The examination of tissue during a surgical procedure helps the surgeon determine whether additional tissue should be removed or further surgery is required.

Cryostats operate like microtomes for tissue sectioning, but the tissue is not processed chemically to prepare it for sectioning. Instead, freezing makes the tissue solid enough to be sliced. Excess tissue from the frozen section sample is then sent to the histology laboratory for chemical tissue processing, sectioning, staining, and more extensive evaluation by a pathologist.

The excised tissue is embedded in frozen section media for faster freezing and to create a bond between the tissue and the specimen stage or specimen chuck that holds it. The media also helps reduce tissue curling and artifacts from ice formation.

Cryostats may be electrical or, less commonly, use liquid nitrogen or helium to rapidly freeze the tissue specimens. Although more frequently used in healthcare, cryostats may also be used in research settings.

Current models may also feature:

Automatic UV disinfection
Motorized handwheel
Peltier temperature controls
Multiple freezing stations
Touchscreen operation
Ergonomic design
Emergency stop via foot pedal or control panel
Debris removal systems

Additional cryostat accessories and replacement cryostat parts and blades are also available

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Epredia™ CryoStar™ NX50 Cryostat With Blade Carrier

Manual cryostat designed to accommodate the needs of the routine clinical laboratory by offering a form-fitting ergonomic design, with optional height adjustment, vacutome and cold D disinfection.

Pricing & Availability
Specifications

Product Type	Cryostat with Carrier

Epredia™ CryoStar™ NX70 Cryostat

Accommodate the needs of both research and clinical laboratories with the Epredia™ CryoStar™ NX70.

Pricing & Availability
Specifications

Width (English)	29.7 in.
Chamber Temperature	-60°C Max.
Cutting Window	Manually adjusted to specimen size
Width (Metric)	75.5 cm
Includes	All standard features: electronic height adjustment, Rapid Response Temperature Control, multi-axis specimen orientation, motorized sectioning, specimen retraction, form-fitting design
Lighting	LED
Defrost	Programmed/Immediate
Fine Section Resolution	0.5 to 5μm in 0.5μm steps; 5 to 10μm in 1μm steps; 10 to 20μm in 2μm steps; 20 to 50μm in 5μm steps; 50 to 100μm in 10μm steps
Specimen Orientation	x- and y-axes universal 7° with zero positioning; z-axis up to 360°
Certifications/Compliance	Certificate of Hygiene, CE Marked
Vertical Cutting Stroke	64 mm
Weight (Metric)	200 kg
Height (English)	32.3 to 44.0 in.
Height (Metric)	82 to 112 cm
Specimen Approach Manual	3 mm/sec. max. (variable speed by joystick control)
Depth (English)	39.4 in.
Cutting Speed	0 to 256 mm/sec.
Sectioning Range	0.5 to 100μm (Fine Section), 5 to 500μm (Trim Section)
Horizontal Specimen Movement	48 mm
Clearance Angle Adjustment	Disposable blade carrier 8 to 16°
Specimen Retraction	20 μm
Trim Section Resolution	0.5 to 5μm in 0.5μm steps, 5 to 10μm in 1μm steps, 10 to 20μm in 2μm steps, 20 to 50μm in 5μm steps, 50 to 100μm in 10μm steps
Depth (Metric)	100 cm
Weight (English)	440 lb.
Cutting Drive	Manual and motorized, electronically controlled
Specimen Temperature Control	-50°C to +10°C at +20°C Room Temperature (decrease 0.7°C/1°C room temp. increase)
Coarse Feed	Motorized (on/off)
Knife Temperature Control	-35°C to -5°C at 20°C room temp. (decrease 0.5°C/1°C room temp. increase)
Display	Integrated Color LCD Touchscreen

Epredia™ HM525 NX Cryostat, HM525 NX, 115V 60Hz

Deliver high quality routine results comfortably and efficiently with the Epredia™ Microm HM525 NX Cryostat, a high performance routine cryostat.

Pricing & Availability
Specifications

Height (Metric)	1150 mm
Depth (English)	25.19 in.
Chamber Temperature	-35°C +/-3°C Max. at +20°C Room Temperature
Trim Section Resolution	5 to 30μm in 5μm steps; 30 to 100μm in 10μm steps; 100 to 200μm in 20μm steps; 200 to 500μm in 50μm steps
Depth (Metric)	760 mm
Defrost	Programmed/Immediate
Weight (English)	315.2 lb.
Certifications/Compliance	CSA, CE
Weight (Metric)	143 kg
Height (English)	45.3 in.
Sectioning Range	5 to 500μm

Epredia™ Microm HM525 NX Cryostat

A high performance routine cryostat with intuitive software and touchscreen for simple, efficient operation

Pricing & Availability
Specifications

Electrical Requirements	115 V 60 Hz

Epredia™ CryoStar™ NX50 Cryostat

Manual cryostat designed to accommodate the needs of the routine clinical laboratory by offering a form-fitting ergonomic design, with optional height adjustment, vacutome and cold D disinfection.

Pricing & Availability
Specifications

Height (Metric)	82 to 112 cm
Depth (English)	39.4 in.
Width (English)	29.7 in.
Cutting Window	Manually adjusted to specimen size
Width (Metric)	75.5 cm
Sectioning Range	0.5 to 100μm (Fine Section), 5 to 500μm (Trim Section)
Horizontal Specimen Movement	48 mm
Clearance Angle Adjustment	Disposable blade carrier 8 to 16°
Specimen Retraction	20 μm
Trim Section Resolution	5 to 30μm in 5μm steps; 30 to 100μm in 10μm steps; 100 to 200μm in 20μm steps; 200 to 500μm in 50μm steps
Product Type	Cryostat
Depth (Metric)	100 cm
Defrost	Programmed/Immediate
Cryobar Cooling	-57°C ±3°C (-70.6°F +35.6° to -26.6°F) at +20°C/+58°F ambient
Fine Section Resolution	0.5 to 5μm in 0.5μm steps; 5 to 10μm in 1μm steps; 10 to 20μm in 2μm steps; 20 to 50μm in 5μm steps; 50 to 100μm in 10μm steps
Specimen Orientation	y-axes 8° adjustable for increased stability; Z axis adjustable 360°
Weight (English)	440 lb.
Cutting Drive	Manual
Vertical Cutting Stroke	64 mm
Specimen Temperature Control	43 ±2°C at +20°C Room Temperature
Blade Holder Approach	Stepper motor controlled through simple touch screen display
Coarse Feed	Motorized (on/off)
Weight (Metric)	200 kg
Height (English)	32.3 to 44.0 in.
Knife Temperature Control	-27°C; to -20°C ±2°C at +20° to +30°C Room Temperature