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Filtered Search Results
Medchemexpress LLC Seco rapamycin sodium salt | 148554-65-8 | 90.6% | 936.15 g/mol | C51H78NNaO13 | 10 MG
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Seco Rapamycin sodium salt is the ring-opened derivative of rapamycin supplied as the monosodium salt. It is reported not to affect mTOR function and has been characterized in vitro for NADPH-dependent conversion to dihydro sirolimus (M2) in human tissue homogenates and Caco-2 models. Supplied as a white to yellow solid with specified purity and recommended low-temperature storage.
- Ring-opened derivative of rapamycin
- Reported not to affect mTOR function
- Metabolized in vitro to dihydro sirolimus (M2) in an NADPH-dependent manner
- Provided as a monosodium solid salt
- Recommended storage -20°C; protect from light and store under nitrogen
- Suitable for in vitro research and metabolic studies
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eMolecules 1263094-00-3 | Medchem Express | 7-Chlorokynurenic acid (sodium salt) | 10mg | 446256128 | HY-100811A | MFCD12195840 | 245.59 | C10H5ClNNaO3
Medchem Express | DGAT1-IN-1 | 5mg | 446261225 | HY-12425 | 1449779-49-0 | MFCD28167832 | 551.566 | C30H28F3N3O4
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eMolecules 152946-68-4 | Medchem Express | Nolatrexed dihydrochloride | 5mg | 448038994 | HY-108474 | 357.25 | C14H14Cl2N4OS
Medchem Express | CLK1-IN-1 | 5mg | 446257954 | HY-103082 | 2123491-32-5 | 409.424 | C24H16FN5O
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Abcam Rapamycin, mTORC1 comple x inhibitor, 5MG
MW 914.2 Da, Purity >98%. Immunosuppressant and antifungal agent . Complexes with FKBP-12 and inhibits mTOR (mammalian target of rapamycin). In complex with its cellular receptor, the FK506-binding protein (FKBP12), rapamycin binds and inhibits the function of the mammalian target of rapamycin (mTOR).
The product is subject to the following: Abcam Restricted Use Statement
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Medchemexpress LLC JH-X-119-01 | 2227368-54-7 | 99.0% | 452.46 g/mol | C25H20N6O3 | 50 MG
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JH-X-119-01 is a potent, selective small-molecule inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) with an in vitro IC50 of 9 nM. It is supplied for research use as a powder or as a 10 mM solution in DMSO, with a reported purity of 99.03% and molecular weight of 452.46 g/mol.
- Potent IRAK1 inhibition (IC50 9 nM).
- High reported purity (99.03%).
- Molecular weight 452.46 g/mol.
- Available as powder and as 10 mM DMSO solution.
- Multiple packaging sizes from milligram to gram scale.
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eMolecules 322413-04-7 | (E)-2-(4-METHYLBENZYLIDENEAMINO)-1-PHENYLETHANOL | AstaTech | MFCD00768776 | 239.318 | C16H17NO | 95.000 | Cc1ccc(\C=N\CC(O)c2ccccc2)cc1 | 1g | 112531815
(E)-2-(4-METHYLBENZYLIDENEAMINO)-1-PHENYLETHANOL | AstaTech | 322413-04-7 | MFCD00768776 | 239.318 | C16H17NO | 95.000 | Cc1ccc(\C=N\CC(O)c2ccccc2)cc1 | 1g | 112531815
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Sigma Aldrich Fine Chemicals Biosciences Loratadine United States Pharmacopeia (USP) Reference Standard | 79794-75-5 | MFCD00672869 | 200MG
Loratadine United States Pharmacopeia (USP) Reference Standard | Mol Wt: 382.88 | 79794-75-5 | MFCD00672869 | 200MG
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Selleck Chemical LLC CZC-54252
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CZC-54252 is a potent and selective LRRK2 inhibitor with IC50s of 1 28 nM and 1 85 nM for human wild type LRRK2 and G2019S LRRK2 respectively
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Medchemexpress LLC SCD1 inhibitor-1 | 1069094-65-0 | 99.9% | 451.54 | 10 MG
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SCD1 inhibitor-1 (Compound 48) is an orally active and liver-selective inhibitor of stearoyl-CoA desaturase 1 (SCD1) with an IC50 of 8.8 nM for recombinant human SCD1 enzyme. SCD1 inhibitor-1 can be used in the study of diseases such as diabetes, hepatic steatosis and obesity.
- Orally active and liver-selective inhibitor of stearoyl-CoA desaturase 1 (SCD1).
- IC50 of 8.8 nM for recombinant human SCD1 enzyme.
- Improved effect in high-fat mice models (3-10 mg/kg; oral administration; 43 days), showing improved glucose tolerance in a dose-dependent manner and decreased body weight.
- Improved effect in high-sucrose rat models (1-10 mg/kg; oral administration; single dose), inhibiting SCD1 inhibitory activity in a dose-dependent manner in epididymal adipose tissue and the liver 6 hours after oral administration.
- Selective tissue distribution of liver/eyelid.
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Apexbio Technology LLC Napabucasin 83280-65-3 5mg
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Napabucasin (CAS 83280-65-3) also known as BBI608 is an orally bioavailable small molecule that targets STAT3 (signal transducer and activator of transcription 3) a regulator of cancer cell pluripotency and survival Napabucasin inhibits STAT3 transcriptional activity with IC50 values of 0 395 M in bulk cancer cells and 0 142 M in cancer stem cells In vitro it reduces cell viability migration colony formation and stemness marker expression induces cell cycle arrest and apoptosis and sensitizes cells to chemotherapy In vivo napabucasin suppresses tumor growth and recurrence and limits self-renewal and metastasis of cancer stem cells in xenograft models This compound is widely utilized in studies of cancer stemness and STAT3-driven oncogenesis
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eMolecules 1261590-48-0 | Medchem Express | Duvelisib (R enantiomer) | 5mg | 446268210 | HY-17044A | MFCD30187518 | 416.87 | C22H17ClN6O
Ambeed | 2-Ethylhexyl 3-(35-di-tert-butyl-4-hydroxyphenyl)propanoate | 250mg | 696731383 | A1364274 | 144429-84-5 | 390.608 | C25H42O3
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Medchemexpress LLC PF-4191834 50mg | 1029317-21-2 | 393.50 g·mol⁻¹ | C22H23N3O2S | 50 MG
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PF-4191834 is an orally active, non-iron-chelating, non-redox inhibitor of 5-lipoxygenase (5-LOX) used in research to probe leukotriene biosynthesis and 5-LOX-mediated pathways. It is supplied as a solid, characterized by high purity, and has documented solubility and storage recommendations for both powder and solution forms.
- Submicromolar potency against 5-LOX (reported IC50 ≈ 229 nM).
- High purity (reported 99.77%).
- Soluble in DMSO at approximately 100 mg/mL; in vivo formulation protocols documented.
- Stable as powder when stored at -20°C (up to 3 years) or 4°C (up to 2 years).
- Available in small research pack sizes including 50 mg.
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AdipoGen Lactacystin, 133343-34-7, MFCD01076525, 200 ug
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MF: C15H24N2O7S, MW: 376.4, ≥98%, Appearance: White to off-white solid. Induces neuritogenesis, Apoptosis inducer, Anticancer compound, and Induces differentiation and inhibits cell cycle progression in several tumor cell lines.
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Medchemexpress LLC HY-10009 5mg Medchemexpress, Semagacestat CAS:425386-60-3 Purity:>98%
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Medchemexpress, HY-10009 5mg Semagacestat CAS:425386-60-3 Semagacestat is a γ-secretase inhibitor, inhibits β-amyloid ( Aβ42 ), Aβ38 and Aβ40 with IC 50 of 10.9, 12 and 12.1 nM, respectively; also inhibits Notch signaling with IC 50 of 14.1 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-100792 10mg Medchemexpress, URB602 CAS:565460-15-3 Purity:>98%
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Medchemexpress, HY-100792 10mg URB602 CAS:565460-15-3 URB602 is a selective monoacylglycerol lipase ( MGL ) inhibitor, which inhibits rat brain MGL with IC 50 of 28±4 μM through a noncompetitive mechanism. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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