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Filtered Search Results
Medchemexpress LLC (Z)-orantinib ((Z)-SU6668) | 210644-62-5 | MFCD09743433 | 99.4% | 310.35 g/mol | C18H18N2O3 | 100 MG
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(Z)-Orantinib is a research-grade small-molecule tyrosine kinase inhibitor with activity against VEGFR, PDGFR, and FGFR family kinases. It is supplied as a solid (orange to red) for use in in vitro and in vivo laboratory experiments and is intended for research use only.
- Potent inhibitor of VEGFR, PDGFR, and FGFR kinases.
- Supplied as an orange to red solid suitable for laboratory research.
- High purity (99.4%) as determined by supplier analysis.
- Chemical formula C18H18N2O3; molecular weight 310.35 g/mol.
- Recommended storage: powder at -20°C for long-term stability.
- For research use only; not for human or clinical application.
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Medchemexpress LLC HY-13566A 5mg Medchemexpress, Belotecan (hydrochloride) CAS:213819-48-8 Purity:>98%
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Medchemexpress, HY-13566A 5mg Belotecan (hydrochloride) CAS:213819-48-8 Belotecan hydrochloride (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic and water-soluble camptothecin derivative. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Geldanamycin 30562-34-6 100mg
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Geldanamycin is an antibiotic from Streptomyces hygroscopicus that inhibits heat shock protein 90 (Hsp90) by binding to its ATP-binding pocket This disruption affects protein folding and stabilization impacting cell proliferation stress response and tumor biology Geldanamycin is used as a molecular tool in these studies and has activity against various microbes including bacteria fungi protozoa and nematodes IC50 values range from nanomolar to micromolar levels depending on the cell line and conditions It is also applied in research on vascular relaxation glucocorticoid receptor modulation and inflammation-related signaling pathways
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Medchemexpress LLC HY-17397 100mg Medchemexpress, Strontium Ranelate CAS:135459-87-9 Purity:>98%
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Medchemexpress, HY-17397 100mg Strontium Ranelate CAS:135459-87-9 Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate also can activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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U.S. Pharmacopeia Tobramycin, 32986-56-4, MFCD00077885, 350mg
Molecular formula C18H37N5O9, Molecular weight 467.52, Melting Point 548.6 °F (287 °C), Synonyms: Nebramycin Factor 6
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Medchemexpress LLC Tomatidine hydrochloride | 6192-62-7 | MFCD00133866 | 99.6% | 452.11 | C27H46ClNO2 | 10 MG
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Tomatidine hydrochloride is the hydrochloride salt of tomatidine, a steroidal alkaloid used as a research reagent that inhibits NF-κB and modulates JNK signaling and has been reported to induce autophagy in mammalian cells and Caenorhabditis elegans. It is supplied as a high-purity small molecule for laboratory use.
- Hydrochloride salt, molecular formula C27H46ClNO2.
- Molecular weight 452.11.
- CAS number 6192-62-7.
- Purity 99.6% (reported).
- Reported activities: NF-κB inhibition, JNK modulation, autophagy induction.
- Suitable for cell biology and signaling pathway studies.
- Store sealed at 4°C, protected from moisture and light.
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Medchemexpress LLC (3S,4S)-PF-06459988 | 1858291-14-1 | 99.0% | 10 MG
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(3S,4S)-PF-06459988 is the S-enantiomer of PF-06459988, provided as a high-purity research compound that irreversibly inhibits the T790M mutant form of the epidermal growth factor receptor (EGFR). It is intended for biochemical and cellular studies of mutant EGFR signaling, inhibitor selectivity, and related preclinical research applications.
- Has selectivity for T790M mutant EGFR.
- Acts as an irreversible EGFR inhibitor.
- Supplied as a high-purity powder suitable for research use.
- Soluble in DMSO at high concentration; in vivo formulations reported.
- Stable under recommended frozen storage; follow solvent storage guidelines for prepared solutions.
- Suitable for biochemical assays, cellular studies, and selectivity profiling.
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Medchemexpress LLC HY-111455 5mg Medchemexpress, LP-211 CAS:1052147-86-0 Purity:>98%
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Medchemexpress, HY-111455 5mg LP-211 CAS:1052147-86-0 LP-211 is a selective and blood−brain barrier penetrant 5-HT7 receptor agonist, with a Ki of 0.58 nM, with high selectivity over 5-HT1A receptor (Ki, 188 nM) and D2 receptor (Ki, 142 nM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Cefetamet | 65052-63-3 | 99.4% | 397.43 | C14H15N5O5S2 | 10 MG
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Cefetamet is a cephalosporin antibiotic research compound that acts as the active metabolite of cefetamet pivoxil. It binds bacterial penicillin-binding proteins and exhibits activity against a range of Gram-negative and Gram-positive bacteria. It is supplied as a solid in small-mass packs and as DMSO solutions for assay use.
- Cephalosporin antibiotic with defined antibacterial activity.
- Active metabolite used in studies of penicillin-binding proteins.
- High purity suitable for biochemical and microbiological research.
- Offered in small solid packs and 10 mM DMSO solutions for assays.
- Well characterized by CAS number 65052-63-3 and molecular weight 397.43.
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Medchemexpress LLC HY-109035 10mg Medchemexpress, Inarigivir soproxil CAS:942123-43-5 Purity:>98%
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Medchemexpress, HY-109035 10mg Inarigivir soproxil CAS:942123-43-5 Inarigivir soproxil is an agonist of innate immunity and shows potent antiviral activity against resistant hepatitis C virus (HCV) variants, with EC50s of 2.2 and 1.0 μM for HCV 1a/1b in cells of genotype 1 HCV replicon systems. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Mirabegron | 223673-61-8 | MFCD11100356 | 99.9% | 396.51 | 100 MG
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Mirabegron is a selective β3-adrenoceptor agonist, demonstrating potent bladder relaxant properties. It is an orally active compound known for its ability to increase cyclic AMP accumulation, primarily targeting β3-adrenoceptors with an EC50 of 22.4 nM. This compound exhibits significant selectivity, showing minimal agonistic effects on β1- and β2-adrenoceptors.
- Selective β3-adrenoceptor agonist
- Increases cyclic AMP accumulation
- Potent bladder relaxant compound
- Exhibits high selectivity over β1- and β2-adrenoceptors
- Effective in treating overactive bladder symptoms such as urgency and frequency
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MEDCHEMEXPRESS LLC LY3214996 5MG
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501871836 LY3214996 5MG
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Medchemexpress LLC HY-13553 5mg Medchemexpress, Anidulafungin CAS:166663-25-8 Purity:>98%
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Medchemexpress, HY-13553 5mg Anidulafungin CAS:166663-25-8 Anidulafungin is a new semisynthetic echinocandin with antifungal potency. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Clarithromycin 81103-11-9 10mM (in 1mL DMSO)
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Clarithromycin is a macrolide antibiotic exhibiting inhibitory activity against the cytochrome P450 isoform CYP3A a critical enzyme involved in drug metabolism Through CYP3A inhibition clarithromycin elevates the plasma concentrations of substrates notably statins thereby potentially altering their pharmacokinetic profiles Clarithromycin demonstrates potent CYP3A inhibition with an approximate IC50 value of 32 M making it suitable for in vitro and in vivo research investigating drug-drug interaction mechanisms and pharmacokinetic studies involving CYP3A-dependent pathways Experimental applications include assessing clarithromycin s impact on hepatic CYP3A activity evaluating the metabolic stability of CYP substrates and characterizing interaction risks between concurrent medications that share CYP3A-mediated metabolic routes
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Medchemexpress LLC HY-101922 5mg Medchemexpress, IRAK4-IN-1 CAS:1820787-94-7 Purity:>98%
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Medchemexpress, HY-101922 5mg IRAK4-IN-1 CAS:1820787-94-7 IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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