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Filtered Search Results
Medchemexpress LLC Solithromycin | 760981-83-7 | 99.85% | 845.01 | 100 MG
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Solithromycin is an orally bioavailable, effective antimicrobial agent. It inhibits cell viability, protein synthesis, and growth rate against various bacteria, including *Streptococcus pneumonia*, *Staphylococcus aureus*, and *Haemophilus influenzae*. This macrolide binds to the large 50S subunit of the ribosome, thereby inhibiting protein biosynthesis.
- Orally bioavailable and effective antimicrobial agent
- Inhibits protein synthesis by binding to the large 50S ribosomal subunit
- Macrolide
- Inhibits TNFa and CXCL8 release
- Reduces MMP9 activity
- Suppresses lipopolysaccharide-induced TNFa release and PMA-induced MMP9 activity
- Does not affect cell viability in monocytic U937 and PBMC cells
- Inhibits inflammatory cells accumulation and pro-MMP9 production in cigarette smoke-exposed mice
- Inhibits cigarette smoke-induced neutrophilia and pro-MMP9 production
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![Medchemexpress LLC 2-thiophenecarboxamide, 3-[(4-chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]- | 1203680-76-5 | 100.0% | 371.88 | 50MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000387926-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 2-thiophenecarboxamide, 3-[(4-chlorophenyl)methoxy]-N-[(1S)-1-phenylethyl]- | 1203680-76-5 | 100.0% | 371.88 | 50MG
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AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor. It exhibits IC50 values of 0.34 μM for Mouse SHIP2, 0.62 μM for Human SHIP2, 13 μM for Human SHIP1, and >50 μM for Human PTEN, Human synaptojanin, and Human myotubularin. This compound enhances the phosphorylation of Akt, glucose consumption, and glucose uptake, and it activates intracellular insulin signaling pathways.
- Potent, orally active, selective SHIP2 phosphatase inhibitor.
- Increases Akt phosphorylation.
- Enhances glucose consumption and uptake.
- Activates intracellular insulin signaling pathways.
- Suitable for diabetes research.
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Medchemexpress LLC Neomycin (sulfate) | 1405-10-3 | 99.9% | 1 ML
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Neomycin (sulfate) | 1405-10-3 | 99.9% | 1 ML
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Sigma Aldrich Fine Chemicals Biosciences Diphenhydramine hydrochloride British Pharmacopoeia (BP) Reference Standard | 147-24-0 | MFCD00012479 |
Diphenhydramine hydrochloride British Pharmacopoeia (BP) Reference Standard | Mol Wt: 291.82 | 147-24-0 | MFCD00012479 |
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Medchemexpress LLC Crbn modulator-1 | 2407829-65-4 | MFCD33029299 | 98.0% | C17H12N2O5 | 10MG
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CRBN modulator-1 is a thalidomide analog that modulates cereblon (CRBN), an E3 ligase substrate receptor. Described in WO2020006262A1 (compound 10), the compound has reported biochemical activity (IC50 3.5 μM; Ki 0.98 μM) and is supplied as a solid for research use with supporting analytical documentation.
- Acts as a cereblon modulator with IC50 3.5 μM and Ki 0.98 μM.
- Provided as a solid powder suitable for research applications.
- High purity, 98.0%, with supporting analytical data available.
- Molecular formula C17H12N2O5; molecular weight 324.29 g/mol.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Documentation includes datasheet, certificate of analysis, NMR, HPLC, and MS.
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Medchemexpress LLC Ditolylguanidine | 97-39-2 | 99.66% | C15H17N3 | 500 MG
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Ditolylguanidine (1,3-Di-o-tolylguanidine; DTG) is an agonist of sigma receptor (σ1/σ2 receptor) with Ki values of 69 and 21 nM for σ1 and σ2 receptors, respectively. It effectively inhibits the growth of small cell lung cancer cells and can be used for lung cancer research.
- Agonist of sigma receptor (σ1/σ2 receptor)
- Effectively inhibits the growth of small cell lung cancer cells
- Suitable for lung cancer research
- Inhibits N-(2-piperidinoethyl)4-iodobenzamide) (IPAB)
- Affects micturition intervals and threshold pressure in anaesthetized rats
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![eMolecules 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine | 865362-74-9 | MFCD14585805 | 10mg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502137536.JPG-250.jpg)
eMolecules 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine | 865362-74-9 | MFCD14585805 | 10mg
Ambeed | 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine | 10mg | 514326560 | A867944 | | 865362-74-9 | MFCD14585805 | 327.351 | C18H13N7
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Apexbio Technology LLC Merimepodib 198821-22-6 2mg
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Merimepodib (CAS 198821-22-6) is a small-molecule inhibitor targeting inosine monophosphate dehydrogenase (IMPDH) It is designed to inhibit IMPDH thereby blocking the conversion of inosine monophosphate to xanthosine monophosphate and impacting guanine nucleotide biosynthesis Merimepodib exerts its biological activity primarily through noncompetitive inhibition of IMPDH In in vitro studies Merimepodib demonstrates antiproliferative effects suppressing lymphocyte cell growth at approximately 100 nM It also shows antiviral activity with IC50 values of 0 38 M for HBV 0 80 M for HCMV 1 0 M for EMCV and 1 14 M for RSV Based on these pharmacological properties Merimepodib holds research potential in antiviral therapy immunosuppression and transplant rejection models
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Sigma Aldrich Fine Chemicals Biosciences Undecanoic acid >=99%, FG | 112-37-8 | MFCD00002730 | 1KG
Undecanoic acid >=99%, FG | Purity: >=99% | Mol Wt: 186.29 | 112-37-8 | MFCD00002730 | 1KG
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Medchemexpress LLC JP1302 dihydrochloride | 1259314-65-2 | MFCD10565599 | 99.9% | 441.40 g/mol | C24H26Cl2N4 | 10 MG
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JP1302 dihydrochloride is a dihydrochloride salt small molecule antagonist of the human α2C-adrenoceptor supplied as a solid for research use.
- High purity (99.9%).
- Potent, selective α2C-adrenoceptor antagonist (Kb 16 nM; Ki 28 nM).
- Brown to reddish brown solid appearance.
- Soluble in water and DMSO at research-relevant concentrations (see datasheet for details).
- Store sealed away from moisture; in solvent store at -80°C for up to 6 months or -20°C for up to 1 month.
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Medchemexpress LLC HY-100371 5mg Medchemexpress, (RS)-MCPG CAS:146669-29-6 Purity:>98%
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Medchemexpress, HY-100371 5mg (RS)-MCPG CAS:146669-29-6 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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![eMolecules Medchem Express / Boc-MLF (TFA) / 5mg / 446276223 / HY-103473A / / / [null] / 623.690 / C27H40F3N3O8S](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502455572.PNG-250.jpg)
eMolecules Medchem Express / Boc-MLF (TFA) / 5mg / 446276223 / HY-103473A / / / [null] / 623.690 / C27H40F3N3O8S
Medchem Express / Boc-MLF (TFA) / 5mg / 446276223 / HY-103473A / / / [null] / 623.690 / C27H40F3N3O8S
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Medchemexpress LLC HY-15592 10mg Medchemexpress, Cabotegravir CAS:1051375-10-0 Purity:>98%
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Medchemexpress, HY-15592 10mg Cabotegravir CAS:1051375-10-0 0 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-12516 10mg Medchemexpress, Desogestrel CAS:54024-22-5 Purity:>98%
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Medchemexpress, HY-12516 10mg Desogestrel CAS:54024-22-5 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC ESI-09 | 263707-16-0 | 99.7% | 330.77 | 50 MG
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ESI-09 | 263707-16-0 | 99.7% | 330.77 | 50 MG
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