Medchemexpress, HY-100036 2mg MK-4101 CAS:935273-79-3 MK-4101 is a Smoothened (SMO) antagonist ( IC 50 of 1.1 µM for 293 cells ) and also a potent inhibitor of the hedgehog pathway ( IC 50 of 1.5 µM for mouse cells; IC 50 of 1 µM for KYSE180 oesophageal cancer cells). MK-4101 has robust antitumor activity that inhibits tumor cell proliferation and induces extensive apoptosis [1] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.