Cell Culture Growth Factors and Hormones
STEMCELL Technologies Human Recombinant CNTF, ACF, Size: 1000 µg
Use ciliary neurotrophic factor (CNTF) to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into astrocytes (Krencik & Zhang. Nat Protoc, 2011). CNTF binds to its receptor CNFTRα and induces a heterodimer formation with the IL-6 receptor gp130 and LIF receptor (LIFR)-β, and activates the JAK/STAT, ERK, and the PI3K signaling cascades (Schuster et al. J Biol Chem, 2003). CNTF plays an important role in neurogenesis and the differentiation of neural stem cells and has been suggested to possess a therapeutic role in treating neurological disorders (Ding et al. J Alzheimers Dis, 2013.) CNTF also has been reported to protect oligodendrocytes from death induced by apoptosis (Louis et al.). Human recombinant CNTF from STEMCELL is animal component free and comes lyophilized with ≥ 95% purity; specific activity EC50 ≤ 200 ng/mL; endotoxin levels verified ≤ 0.2 EU/μg protein. Alternative name: Ciliary neurotrophic factor. Visit STEMCELL.com for more information.
American Research Products Inc Mouse Tumor necrosis factor a
Mouse Tumor necrosis factor a TNF-a ELISA KIT from CUSABIO Detection Range 62 5 pg/mL-4000 pg/mL Sensitivity 15 6 pg/mL Sample cell culture supernates tissue homogenates Method Sandwich
American Research Products Inc Mouse Tumor necrosis factor a
Mouse Tumor necrosis factor a TNF-a ELISA KIT from CUSABIO Detection Range 15 6 pg/ml-1000 pg/ml Sensitivity 3 9 pg/ml Sample serum plasma cell culture supernates tissue homogenates Method Sandwich
American Research Products Inc BoVine Insulin like growth fac
BoVine Insulin-like growth factor II (IGF2) ELISA kit from CUSABIO Detection Range 31 25 ng/mL-2000 ng/mL Sensitivity 7 81 ng/mL Sample serum plasma Method Sandwich
Bioworld HUMAN GROWTH HORMONE RELEAS
HUMAN GROWTH HORMONE RELEASING PEPTIDE-2: Growth Hormone Releasing Peptide-2 Source: Description : Synthetic GHRP-2 is a single, non-glycosylated polypeptide chain containing 6 amino acids, having a molecular mass of 746.9 Dalton and ...
Medchemexpress LLC HB-EGF Human CHO 2ug
HB-EGF Protein Human (CHO) is shown to play a role in wound healing cardiac hypertrophy and heart development and function
Meso Scale Discovery U-PLEX Rat FGF-21 ASYQP
The Meso Scale Discovery U-PLEX Rat FGF-21 Assay Kit is an electrochemiluminescent immunoassay for quantifying FGF-21 in rat serum plasma and tissue culture media It uses MSD s SULFO-TAG labels and multi-array technology for sensitive reproducible results The kit includes a 96-well plate with capture antibodies detection antibodies with ruthenium labels calibrators and buffers Sensitivity is 1 3 pg/mL with an upper limit of 10 000 pg/mL It requires 25 L of sample and takes about 3 5 hours Ideal for research in biomarker discovery and disease
Genscript Corporation FGF-R2 Fc Chimera Mouse
Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 is a receptor for fibroblast growth factor and it has important roles in embryonic development and tissue repair especially bone and blood vessels FGFR2 has two naturally occurring isoforms FGFR2IIIb and FGFR2IIIc created by splicing of the third immunoglobulin-like domain FGFR2IIIb is predominantly found in ectoderm derived tissues and endothelial organ lining Like the other members of the fibroblast growth factor receptor family these receptors signal by binding to their ligand and dimerisation (pairing of receptors) which causes the tyrosine kinase domains to initiate a cascade of intracellular signals On a molecular level these signals mediate cell division growth and differentiation
Meso Scale Discovery R-PLEX Human PDGF-C ASY
The R-PLEX Human PDGF-C Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures PDGF-C levels in human serum plasma and cell culture supernatants The assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker solutions calibrator and controls The assay has a typical sensitivity of 0 3 pg/mL and an upper limit of quantification of 10 000 pg/mL
Medchemexpress LLC ROR1 Rat HEK293 H 10ug | 10ug
ROR1 protein is an important member of the Tyr protein kinase family in the protein kinase superfamily and plays a key role as a tyrosine kinase in cell signaling and regulation Its classification emphasizes its importance in phosphorylation events and shares conserved features with related kinases ROR1 Protein Rat (HEK293 His) is the recombinant rat-derived ROR1 protein expressed by HEK293 with C-10 His labeled tag
ILEX LIFE SCIENCES LLC HUMAN FGF2 147AA E.COLI 10 UG
Ilex Life Sciences FGF-2 (FGF-basic) Human (147 aa), E. coli Recombinant Protein (10 ug). DESCRIPTION: Our bioactive FGF-2 (FGF-basic) Human, E. coli Recombinant Protein (147 aa), also known as truncated Fibroblast Growth Factor 2, is a single, non-glycosylated, polypeptide chain with 147 amino acids and 16.5 kDa molecular mass. The FGF-2 is purified by proprietary chromatographic techniques. APPLICATION: FGF basic is a critical component of human embryonic stem cell (hESCs) culture medium; the growth factor is necessary for the cells to remain in an undifferentiated state. FORMULATION: Sterile filtered white powder lyophilized from a sterile filtered solution containing 20mM Tris-HCl, pH 7.6 and 150mM NaCl. PURITY: Greater than 98.0% (SDS-PAGE). BIOACTIVITY: The ED50, Calculated by the dose- dependent proliferation of mouse BALB/c 3T3 cells is < 0.05 ng/ml corresponding to a specific activity of 2.0x107 units/mg. SYNONYMS: FGF-b, Basic fibroblast growth factor, bFGF, HBGF-2.
American Research Products Inc Mouse Tumor necrosis factor re
Mouse Tumor necrosis factor receptor superfamily member 18 (TNFRSF18) ELISA kit from CUSABIO Detection Range 78 pg/ml - 5000 pg/ml Sensitivity 19 5 pg/ml Sample serum plasma tissue homogenates Method Sandwich
STEMCELL Technologies Human Recombinant G-CSF, ACF, Size: 1000 µg
Use granulocyte colony-stimulating factor (G-CSF) to induce the production of neutrophils and the stimulation of granulocyte colony formation from hematopoietic progenitor cells (Metcalf & Nicola. J Cell Physiol, 1983). This cytokine is involved in the mobilization of hematopoietic stem cells from the bone marrow into the periphery through a variety of mechanisms. Examples include transiently reducing SDF-1 expression (Petit et al. Nat Immunol, 2002), activating metalloproteases that cleave VCAM-1 (Levesque et al. Blood, 2001), and releasing norepinephrine from the sympathetic nervous system (Katayama et al. Cell, 2006). Binding of G-CSF to its receptor also leads to activation of the JAK/STAT, MAPK, PI3K, and AKT signal transduction pathways. Human recombinant G-CSF from STEMCELL is animal component-free and comes lyophilized with ≥ 95% purity; EC50 ≤ 0.05 ng/mL; endotoxin levels verified ≤ 1.0 EU/μg protein. Alternative names: Colony-stimulating factor 3, CSF-3, MGI-1G, Pluripoietin.
Biotium Growth Hormone (Pituitary Marker) (GH/1371), CF568 conjugate, 0.1mg/mL
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.