Choose the brand aligned with your industry so we can best serve your needs.
For researchers, scientists, and technical professionals: Your one-stop shop for the complete range of laboratory, production, and safety products and services.
Platelet derived growth factors (PDGfs) are disulfide-linked glycoprotein dimers consisting of two 12.0-13.5kDa polypeptide chains designated as PDGf-A and PDGf-B chains. There are three naturally occurring PDGfs PDGf-AA PDGf-BB and PDGf-AB. Recombinant human PDGf-AA is a 28.5kDa disulfide-linked homodimer of two A chains (250 total amino acids).
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Heat Stable FGF-basic Human is a pleiotropic cytokine and one of the prototypic members of the heparin-binding FGF family Like other FGF family members FGF-basic has the trefoil structure In vivo FGF-basic is produced by a variety of cells including cardiomyocytes fibroblasts and vascular cells FGF-basic regulates a variety of processes including cell proliferation differentiation survival adhesion motility apoptosis limb formation and wound healing FGF-basic can be tumorigenic due to its role in angiogenesis and blood vessel remodeling The angiogenic effects of FGF-basic can produce beneficial cardioprotection during acute heart injury
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Four distinct genes encoding closely related FGF receptors FGF R1-4 are known All four genes for FGF Rs encode proteins with an N-terminal signal peptide three immunoglobulin (Ig)-like domains an acid box region containing a run of acidic residues between the IgI and IgII domains a transmembrane domain and the split tyrosine-kinase domain FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation differentiation and apoptosis Plays an essential role in the regulation of chondrocyte differentiation proliferation and apoptosis and is required for normal skeleton development Regulates both osteogenesis and postnatal bone mineralization by osteoblasts
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More