Cell Lines and Cell Cultures
Innovative Research Inc Pooled Human Saliva 250ml
Pooled Human Saliva from Innovative Research is collected fresh from two or more donors, pooled, and stored frozen. Produced in the salivary glands, human saliva is 99.5% water, but contains many important substances including electrolytes, mucus, antibacterial compounds, and various enzymes.
Innovative Research Inc Single Donor Human Red Blood Cells Unit CPDA1
Single Donor Human Red Blood Cells from Innovative Research are separated from a standard unit (approximately 450ml starting volume) of whole blood. The whole blood is centrifuged into layers, and the red blood cells are manually extracted (no chemical separators are used). The resulting RBC volume is approximately 250ml. These cells are not washed or resuspended. This product is custom-collected per order.
Viral Testing
Each unit is tested for the standard FDA-required viral markers, and found negative for HBsAg, HCV, HIV-1, HIV-2, HIV-1Ag or HIV-1 NAT, ALT, and syphilis using FDA-approved methods. If you would like any further testing or analysis performed prior to shipping, please let us know.Â
Donor Specifications
Innovative Research has a wide network of FDA-approved collection centers across the United States, which allows us to collect from nearly any donor type. We are able to accommodate demographic requests from a variety of genders, race
Genscript Corporation CHO-K1/OX1 Stable Cell Line
The orexin/hypocretin peptides orexin A and orexin B (also known as hcrt-1 and hcrt-2) are 33- and 28-amino acid peptides respectively They are preferentially expressed in hypothalamus The orexins have a range of physiological functions including feeding control energy metabolism neuroendocrine function modulation and sleep-wake cycle regulation The two orexin receptor subtypes OX1 and OX2 both mediate the action of orexin-A and orexin-B and couple efficiently through Gq/11 to activate phospholipase C and lead to elevation of intracellular calcium
Genscript Corporation CHO-K1/NPS1b/G15 Stable Cell
Recombinant CHO-K1 cells stably overexpress human neuropeptide S receptor 1 (NPSR1) isoform B on the surface and contain high levels of G protein G s and G q to couple with the receptor in downstream signaling pathways
Genscript Corporation HEK293/G15 Stable Cell Line
HEK293/G 15 is a HEK293 cell line stably expressing the G 15 alpha subunit protein which a Gq protein It is used as a host cell for transfection expression of Gs and Gi/o -coupled receptors the constitutively expressed G 15 protein in the cells allows many transfected receptors which normally stimulate/inhibit the cAMP pathway to couple to Gq signal transduction and mobilize intracellular calcium The cell line carries the puromycin resistance gene and is resistant to puromycin
Genscript Corporation CHO-K1/FPR1/G15 Stable Cell L
The formyl peptide receptors (FPR) are a class of G protein-coupled receptors involved in chemotaxis FPR1 is a Gi-coupled GPCR FPR1 is expressed in the vasculature secretory epithelial cells neurons and other tissues FPR is involved in host defense against bacterial infection and in the clearance of damaged cells
Genscript Corporation CHO-K1/CD200 R1 Stable Cell Li
Cell surface glycoprotein CD200 receptor 1 is a protein that in humans is encoded by the CD200R1 gene This gene encodes a receptor for the OX-2 membrane glycoprotein Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner
Genscript Corporation CHO-K1/GNRHR/G15 Stable Cell
The gonadotropin-releasing hormone receptor (GNRHR) also known as the luteinizing hormone releasing hormone receptor (LHRHR) is a member of the seven-transmembrane G-protein coupled receptor (GPCR) family It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes breast ovary and prostate Upon activation the LHRHr stimulates tyrosine phosphatase and elicits the release of LH from the pituitary Evidence exists showing the presence of LHRH and its receptor in extrapituitary tissues as well as a role in progression of some cancers
Genscript Corporation CHO-K1/CD32B Ile232 Stable Cel
Recombinant CHO-K1 cells stably overexpress human immunoglobulin gamma Fc region receptor II-b (Fc RIIb/CD32B 232Ile) on the surface The surface expression of CD32B 232Ile is validated by FACS analysis This stable cell line product is designed for measuring binding affinity and stability of Fc region of antibodies and Fc fusion proteins or antibody based biologics binding with CD32B 232Ile GenScript also offers CD32B 232Thr stable cell line (Cat No M00600) for Fc RIIb polymorphism study
Genscript Corporation HEK293/TP Stable Cell Line
The thromboxane A2 (TxA2) receptor (TP) is a member of the G protein-coupled receptor (GPCR) superfamily which mediates TxA2-induced platelet aggregation and vasoconstriction Dysregulation of TxA2 synthesis and function has been implicated in the pathogenesis of a number of disease states including myocardial ischemia asthma pregnancy-induced hypertension and a variety of kidney diseases TP receptors (Thromboxane A2 receptors) are widely distributed among different organ systems and localized on both cell membranes and in intracellular structures Two isoforms of human TPs have been cloned from placenta (TP ) and endothelium (TP ) that differ in their mechanisms and kinetics of desensitization and internalization The TPs are linked via the Gq/G11 class of G proteins to phospholipase C (PLC) which hydrolyzes phosphoinositides to two potent second messengers inositol 1 4 5-trisphosphate which leads to an increase in cytoplasmic free calcium and diacylglycerol (DAG) which a
iQ Biosciences Human Natural T Regulatory Cells, 1M cells/vial
High-quality, high-viability (typically > 80%) natural human T regulatory cells isolated from PBMCs with confirmed suppressive capacity. Used for a wide variety of in-vitro applications, including co-culture suppression and cytotoxicity assays. All orders come with an iQ Certificate of Analysis.
Brainxell Inc Spinal Astrocytes (Human iPSC-Derived, Male Line, 2M)
Spinal astrocytes derived from iPSC line WC-30, male. Contents: 1 vial of ≥2x10^6 viable cryopreserved cells. Marker Expression and Morphology: Spinal Astrocytes (BX-0650) express key astrocyte markers GFAP (green) at >80% and exhibit mature process-bearing morphologies (shown here with a DAPI stain). Labelling by the spinal-specific marker HOXB4 (red) with a Hoescht stain highlights the regional specificity of the Spinal Astrocytes. Function: Spinal Astrocytes promote mature motor neuron activity. Co-culturing motor neurons with spinal astrocytes promotes maximal calcium influx within 10 days. Co-culture spinal astrocytes with motor neurons also accelerates the development of activity recorded by multi-electrode array. Related diseases: Amyotrophic Lateral Sclerosis (ALS), Spinal muscular atrophy (SMA), & Spinal Cord Injury.
Genscript Corporation CHO-K1/PAC1/G15 Stable Cell L
Recombinant CHO-K1 cells stably overexpress human pituitary adenylate cyclase-activating polypeptide type I receptor (PAC1) on the surface and contain high levels of G protein G q and G s to couple with the receptor in downstream signaling pathways
Amsbio LLC MDA-MB-231 / Luciferase (Puro) Stable Cell Line
MDA-MB-231 / Luciferase (Puro) Stable Cell Line