Cell Lines and Cell Cultures
Eurofins Discoverx PathHunter CHO-K1 MC5R β-Arrestin Cell Line, 2 vials. (93-0231C2)
The PathHunter MC5R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-MSH) based activation of MC5R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC5R and EA-tagged β-Arrestin-2. Activation of MC5R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS MC5R β-Arrestin Cell Line, 2 vials. (93-0231C3)
The PathHunter MC5R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. α-MSH) based activation of MC5R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC5R and EA-tagged β-Arrestin-2. Activation of MC5R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 PPYR1 (NPY4R) β-Arrestin Cell Line, 2 vials. (93-0233C2)
The PathHunter PPYR1 (NPY4R) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. pancreatic polypeptide) based activation of PPYR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PPYR1 and EA-tagged β-Arrestin-2. Activation of PPYR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter CHO-K1 ADRA1B β-Arrestin Cell line, 2 vials. (93-0274C2)
The PathHunter ADRA1B cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. epinephrine and norepinephrine) based activation of ADRA1B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged ADRA1B and EA-tagged β-Arrestin-2. Activation of ADRA1B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS NMU1R β-Arrestin Cell Line, 2 vials. (93-0232C3)
The PathHunter nMU1R cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. neuromedin U) based activation of nMU1R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged nMU1R and EA-tagged β-Arrestin-2. Activation of nMU1R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS OPRK1 β-Arrestin Cell Line, 2 vials. (93-0234C3)
The PathHunter OPRK1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dynorphin A) based activation of OPRK1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged OPRK1 and EA-tagged β-Arrestin-2. Activation of OPRK1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx PathHunter U2OS HTR2C β-Arrestin Cell Line, 2 vials. (93-0289C3)
The PathHunter HTR2C cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. serotonin) based activation of HTR2C GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged HTR2C and EA-tagged β-Arrestin-2. Activation of HTR2C stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Zen Bio Inc CRYOPRESERVED HUM SPLENOCYTES,
Cryopreserved Human Splenocytes, (Single Donor) 25 million cells/vial
Biolegend PE/Fire™ 700 anti-mouse CD192 (CCR2) [SA203G11]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
PE/Fire™ 700 anti-mouse CD192 (CCR2) [SA203G11]; Isotype: Rat IgG2b, κ; Reactivity: Mouse; Apps: FC; Size: 100 μg
ATCC Mycobacterium smegmatis
Mycobacterium smegmatis strain W-113 is an aerobic, acid fast bacterium.
ATCC Enterococcus faecalis
Resistant to vancomycin. Sensitive to teicoplanin. CLSI quality control strain for HLAR Gentamicin and HLAR Streptomycin.
ATCC Lactobacillus crispatus
Lactobacillus crispatus strain VPI 7635 was isolated from urine. This whole-genome sequenced bacterium is in homology group A2 and is propagated in a 5% CO2 atmosphere.
ATCC Papilloma virus; genome; Purified plasmid DNA
This clone contains the full length viral genome of HPV-11 inserted into the BamHI site of pBR322. It was constructed by linearizing the virus at the unique BamHI site (nt 7072). Note: The depositor has requested that this deposit be distributed exclusively for scientific and not for commercial purposes.