General Cell Lines and Cell Cultures
ATCC Salmonella enterica; Strain MZ1445; genomic DNA
Genomic DNA isolated from Salmonella enterica subsp. enterica serovar Paratyphi C Strain MZ1445. This bacterial strain is also available as ATCC Catalog No. BAA-1715™.
Eurofins Discoverx ChemiScreen NPBW1 Neuropeptide B/W Receptor Membrane Preparation, 1 vial. (HTS180M)
The ChemiScreen NPBW1 Neuropeptide B/W Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of NPBWR1 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
ATCC AFT024; Embryonic liver; Mouse (Mus musculus)
AFT024 is a fibroblast cell that was isolated from the stroma of a mouse. This cell has applications in stem cell research. SCRC-1007 can serve as a support layer for stem cells at 37°C; however, to ensure that all AFT024 cells are mitotically inactive, irradiation or Mitomycin C treatment is recommended.
ATCC M059J; Malignant Glioblastoma; Human (Homo sapiens)
M059J is a glial cell isolated from the brain of a 33-year-old, male patient with malignant glioblastoma. These cell lines provide helpful model systems in which to study the role of DNA protein kinase in cellular and molecular processes involving DNA damage recognition and repair. It can be used in neuroscience research.
ATCC Human adenovirus 6; Strain: Tonsil 99
Human adenovirus 6 strain Tonsil 99 is propagated in HeLa cells (ATCC CCL-2). This strain was isolated from the tonsil tissue of a 7-year-old girl with chronically infected and enlarged tonsils in Washington, DC. The strain has applications in respiratory disease research.
Eurofins Discoverx ChemiScreen P2Y11 Purinergic Receptor Stable Cell Line, 2 vials. (HTS213C)
The ChemiScreen P2Y11 Purinergic Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY11 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses P2RY11 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of P2RY11, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx Ready-to-Assay NPBW1 Neuropeptide B/W Receptor Frozen Cells, 2 Vials of Cells. (HTS180RTA)
The Ready-to-Assay NPBW1 Neuropeptide B/W Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. neuropeptide B/W) based activation of NPBWR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses NPBWR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NPBWR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Creative Bioarray MOUSE RETINAL PIGMENT EPITHELI
Mouse Retinal Pigment Epithelial Cells0.5 million cells/vial
Eurofins Discoverx 1321N1 P2RY1 Gq Cell Line, 2 vials. (95-1018C6)
The 1321N1 P2RY1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses P2RY1, a naturally Gq coupled GPCR. Upon activation of P2RY1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx RBL-2H3 MRGPRX1 Gq Cell Line, 2 vials. (95-1019C11)
The MRGPRX1 Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. BAM (8-22)) based activation of MRGPRX1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses MRGPRX1, a naturally Gq coupled GPCR. Upon activation of MRGPRX1, the resulting calcium activity can be fluorescently assayed using the Calcium No WashPLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ATCC Eikenella corrodens; 6 x 0.3mL
ATCC BAA-1152-MINI-PACK™ consists of 6 ready-to-use vials of ATCC BAA-1152™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.