General Cell Lines and Cell Cultures
Eurofins Discoverx Ready-to-Assay CXCR2 Chemokine Receptor Frozen Cells, 2 Vials of Cells. (HTS002RTA)
The Ready-to-Assay CXCR2 Chemokine Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. CXCL8/IL8) based activation of CXCR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CXCR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of CXCR2, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter CHO-K1 P2RY6 β-Arrestin Cell Line, 2 vials. (93-0500C2)
The PathHunter P2RY6 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. UTP) based activation of P2RY6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY6 and EA-tagged β-Arrestin-2. Activation of P2RY6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
ACROBiosystems HEK293/Human OX40 Ligand / TNFSF4 Stable Cell Line
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) is also known as glycoprotein Gp34, OX40 ligand (OX40L), TAX transcriptionally-activated glycoprotein 1 and CD252, which belongs to the tumor necrosis factor family. TNFSF4 is the ligand for CD134 and is expressed on such cells as DC2s (a subtype of dendritic cells) enabling amplification of Th2 cell differentiation. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. Furthermore, similar to other TNF superfamily members, membrane-bound OX40 Ligand (TNFSF4) exists as a homotrimer. Human TNFSF4 shares 46% amino acid sequence identity with its mouse counterpart.
Innovative Research Inc Hmn PAI1 Rcmb WT Act 1 mg
Human PAI-1 Recombinant Wild Type Active 1 mg - Human PAI-1 Recombinant Wild Type Active from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 and a purity of >95% as determined by SDS-PAGE. More Details Species Human Target PAI-1 Purification Method Affinity purified Purity >95% as determined by SDS-PAGE Analysis Source E. coli Storage Conditions -70C Additional Information Gentle purification conditions create an active fraction that is greater than 99% pure and 98% active. This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more.
Miltenyi Biotec, Inc. MACSxpress LRSC CD4 TC Iso Kit, h
Untouched isolation of CD4+ cells directly from LRSC
ATCC Staphylococcus aureus; subsp. aureus
Staphylococcus aureus subsp. aureus strain Seattle 1945 is a whole-genome sequenced clinical isolate. This culture is used as a quality control strain for the CAMP test, assay of wood smoke concentrate, evaluation of Mueller-Hinton agar, examination of dairy products, media testing, CLSI disk diffusion, and for Abbott, and Autobac products.
Genscript Corporation CHO-K1/ADRA1A Stable Cell Line
Recombinant CHO-K1 cells stably overexpress human adrenoceptor alpha 1A (ADRA1A) on the surface and contain high levels of G protein G q to couple with the receptor in downstream signaling pathways
ATCC Vascular Cell Basal Medium
Vascular Cell Basal Medium is a sterile, phenol-red-free, liquid tissue culture medium intended for use as one component in a complete ATCC Primary Cell Solutions system. Vascular Cell Basal Medium is designed to support cells derived from normal human large vessels such as human umbilical vein endothelial cells, aortic endothelial cells or aortic smooth muscle cells, as well as microvascular endothelial cells. Also to support the proliferation and plating efficiency of cells derived from the vascular system, Vascular Cell Basal Medium must be supplemented with the appropriate cell-specific growth kit.
Biochain Institute Inc Paraffin Tissue Section Panel - Human Disease Tissue, Alzheimer's Disease, Multi-tissue IV, 7 different tissues, 5 slides/PK
BioChain's FFPE Alzheimer's diseased brain tissue panels are designed for rapidly screening Alzheimer's disease-specific genes or proteins in brain tissues. Tissues are arrayed on positively charged glass slides. Alzheimer's diseased brain tissues on T8236444Alz are selected based on functional regions, while those on T8236445Alz are selected based on anatomical regions. T8236564Alz contains both functional and anatomical regions of Alzheimer's diseased brain tissues. Normal brain tissue panels are also available in the identical format as controls. T8236446Alz contains both Alzheimer's diseased brain tissues and normal brain tissues.
Cell Biologics Immortalized RFP-Expressing Mouse Primary Uterine Microvascular Endothelial Cells
Immortalized RFP-Expressing Mouse Primary Uterine Microvascular Endothelial Cells
Amsbio LLC IL-6 Leeporter™ Luciferase Reporter-NIH 3T3 Cell Line
IL-6 Leeporter™ Luciferase Reporter-NIH 3T3 Cell Line