General Cell Lines and Cell Cultures
Human herpesvirus 2; Strain: ATCC-2011-2; Herpes simplex virus 2
Human herpesvirus 2 strain ATCC-2011-2 is propagated in Vero cells (ATCC CCL-81). The virus was isolated from a clinical sample from a patient positive for HSV-2 in Virginia in 2011. It has applications in infectious disease and sexually transmitted disease research.
ATCC Saccharomyces cerevisiae; Strain: BCY123
Saccharomyces cerevisiae strain BCY123 is provided as an ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant. This strain can be used for protein production in yeast.
ATCC Porphyromonas gingivalis
Porphyromonas gingivalis strain RB22 D-1 is a whole-genome sequenced bacterium that was isolated from a periodontal lesion.
ATCC Metarhizium frigidum
An ampoule containing viable cells (may include spores and mycelia) suspended in cryoprotectant.
ATCC Organoid Growth Kit 1F
ATCC Growth Kits are packages of recombinant proteins, small molecules and other supplements designed to make the preparation of complex media formulations for select organoid culture models easy and reliable. Kit components are supplied as powders to maximize stability and in convenient, pre-portioned, ready-to-reconstitute format that does not require aliquoting or storage once prepared.
ATCC Monkeypox virus; Isolate: hMPXV/USA/MA001/2022
Monkeypox virus strain hMPXV/USA/MA001/2022 is propagated in BSC40 cells (ATCC CRL-2761). This virus was isolated in Massachusetts from a human in May 2022 and it belongs to Clade IIb and lineage B.1.This product requires a VS 16-6A permit, which can be downloaded at the USDA website here. Please submit the completed permit form to SalesPermits@atcc.org with your ATCC sales order number and/or your purchase number noted in the subject line and body of the email.
Eurofins Discoverx ChemiScreen P2Y11 Purinergic Receptor Stable Cell Line, 2 vials. (HTS213C)
The ChemiScreen P2Y11 Purinergic Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY11 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses P2RY11 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of P2RY11, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx ChemiScreen V1B Vasopressin Receptor Membrane Preparation, 1 vial. (HTS136M)
The ChemiScreen V1B Vasopressin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of AVPR1B surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Eurofins Discoverx Ready-to-Assay LPA3 Lysophospholipid Receptor Frozen Cells, 2 Vials of Cells. (HTS130RTA)
The Ready-to-Assay LPA3 Lysophospholipid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. LPA) based activation of LPAR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses LPAR3 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of LPAR3, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.