General Cell Lines and Cell Cultures
ATCC Lactobacillus delbrueckii; subsp. lactis; Strain L110
Lactobacillus delbrueckii subsp. lactis strain L110 was isolated from dairy products. This bacterial type strain is propagated aerobically in lactobacilli MRS medium.
Eurofins Discoverx KILR HT-1080 Cell Pool, 2 vials. (97-1031P043)
The KILR HT-1080 cell pool is a stable, engineered target cell pool, which closely reflects the heterogeneous native protein expression of tumor environments, used to measure direct cell death mediated by immunooncology treatments (e.g. checkpoint modulators, bispecifics, CAR-T, etc.) via Antibody Dependent Cell-mediated Cytotoxicity (ADCC), Complement Dependent Cytotoxicity (CDC), and Antibody Dependent Cell Phagocytosis (ADCP). This product uses EFC technology. The cell pool is a heterogeneous population of HT-1080 cells that overexpress a ProLabel-tagged housekeeping gene. Upon effector cells-mediated cell lysis, ProLabel is released to the media, where EA in the detection kit produces an EFC signal proportional to the level of ProLabel released. This allows for calculation of percent lysis of the KILR cell pool. This stable cell pool is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kilr.
ATCC Candida albicans; Y537
An ampoule containing viable cells (yeast cells, spores, or agar cubes with mycelia) suspended in cryoprotectant.
ATCC Human rhinovirus 1B; Strain: B632
Human rhinovirus 1B strain B632 is propagated in H1HeLa cells (ATCC CRL-1958). This strain was isolated from human throat washings and was deposited by the National Institute of Allergy and Infectious Diseases (NIAID). It has applications in respiratory disease research and infectious disease research.
ATCC Legionella anisa
Legionella anisa strain WA-316-C3 [NCTC 11974] is a whole-genome sequenced type strain that was isolated from tap water in Los Angeles, California.
ATCC Organoid Growth Kit 1B
ATCC Growth Kits are packages of recombinant proteins, small molecules and other supplements designed to make the preparation of complex media formulations for select organoid culture models easy and reliable. Kit components are supplied as powders to maximize stability and in convenient, pre-portioned, ready-to-reconstitute format that does not require aliquoting or storage once prepared.
Genscript Corporation CHO-K1/NK3 Stable Cell Line
Recombinant CHO-K1 cells stably overexpress human tachykinin receptor 3 (NK3) on the surface and contain high levels of G protein G q to couple with the receptor in downstream signaling pathways
Eurofins Discoverx Ready-to-Assay PAR2 Receptor Frozen Cells, 2 Vials of Cells. (HTS037RTA)
The Ready-to-Assay PAR2 Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. PAR2) based activation of F2RL1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses F2RL1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of F2RL1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter CHO-K1 mSSTR2 β-Arrestin Cell Line, 2 vials. (93-0616C2)
The PathHunter mSSTR2 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin 28) based activation of mSSTR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mSSTR2 and EA-tagged β-Arrestin-2. Activation of mSSTR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.
Eurofins Discoverx ChemiScreen 5-HT1B Serotonin Receptor Membrane Preparation, 1 vial. (HTS108M)
The ChemiScreen 5-HT1B Serotonin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of HTR1B surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Cayman Chemical Humn Vascular EndothelIal Gr
INDIGO's assay kits provide the convenience of an all-inclusive cell-based assay system. In addition to VEGFR2 Reporter Cells, provided are two optimized media for use in recovering the cryopreserved cells and for diluting test samples, the reference activator human VEGF-A (165 aa isoform, non-glycosylated), Luciferase Detection Reagents, and a cell culture-ready assay plate.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Brain: Olfactory ( region), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.