General Cell Lines and Cell Cultures
ATCC Enterococcus hirae; Strain FDA M19; genomic DNA
Genomic DNA isolated from Enterococcus hirae Strain FDA M19. This bacterial strain is also available as ATCC Catalog No. 10541™.
Amsbio LLC TLR9/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
TLR9/NF-kB Leeporter™ Luciferase Reporter-HEK293 Cell Line
Eurofins Discoverx InCELL Hunter A549 PYK2 Kinase Binding Cell Line, 2 vials. (96-0042C15)
The InCELL Hunter A549 PYK2 Kinase Binding Cell Line is a stable, engineered cell line for use in studying small molecule drug candidates that engage with kinases. This cell line enables assessment of compound-engagement-based stabilization of PYK2 via detection of PYK2 levels. This product uses EFC technology. The cell line included overexpresses PYK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is denatured by the heat treatment and no EFC signal is produced. When compound engages and heat-stabilizes the target, EA contained in the detection reagent produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
ATCC Klebsiella aerogenes 6 x 0.3mL
ATCC 13048-MINI-PACK™ consists of 6 ready-to-use vials of ATCC 13048™ frozen in 200 μL of glycerol stock, eliminating the need to rehydrate and culture the strain prior to use. Each vial is provided with a 2-D barcode for easy storage and tracking, as well as peel-off labels for fast and reliable recordkeeping.
Promocell GmbH PromoCell hMNC-CB Pellet from > 1 million Normal Human Mononuclear Cells, derived from Cord Blood, single donor
Cell pellet consisting of 1 million cells dissolved in 200µl RNAlater for subsequent RNA, DNA or protein analysis. Note: Cell pellets cannot be revived.Our Cell Pellets are stored in RNAlater – an aqueous protection solution that rapidly permeates the cells and stabilizes cellular DNA, RNA, and proteins and protects them from degradation. This makes our Cell Pellets very useful for a wide range of research applications like gene expression analysis, cell characterization studies, and protein characterization experiments.Each Cell Pellet is made from 1 million cells and is dissolved in 200 µl RNAlater. The Cell Pellets are produced from released cell lots and have the same characteristics, i.e. expression profile or cell type specific antigens. On request, viable cells from the same lot are available for cultivation.
ATCC M059J; Malignant Glioblastoma; Human (Homo sapiens)
M059J is a glial cell isolated from the brain of a 33-year-old, male patient with malignant glioblastoma. These cell lines provide helpful model systems in which to study the role of DNA protein kinase in cellular and molecular processes involving DNA damage recognition and repair. It can be used in neuroscience research.
Eurofins Discoverx PathHunter U2OS KDR Activity Assay, 2 vials. (93-0903C3)
The PathHunter KDR RTK Activity cell line is a stable, engineered cell line for use in studying small molecule drug candidates targeting RTKs. This cell line enables assessment of RTK activation via detection of resulting KDR phosphorylation-induced SH2 domain protein recruitment. This product uses EFC technology. The cell line overexpresses ProLink-tagged fusion of the KDR kinase domain with transmembrane and extracellular ligand binding domain of EGFR; and also an EA-tagged SH2 domain protein. Upon ligand induced receptor activation, cross-phosphorylation of the receptor leads to SH2-EA recruitment and production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/kinases.
STEMCELL Technologies Human Bone Marrow CD34+ Cells, Frozen, Size: 1 x 10^5 cells
Start experiments confidently with ready-to-use, ethically sourced, CD34+ stem and progenitor cells from adult human bone marrow. With personalized service, custom products, flexible delivery times, and the option to reserve entire lots to prescreen cells for applications, we help you get the cells you need. Isolated immunomagnetically using positive selection and cryopreserved in serum-free medium, cells are collected using Institutional Review Board (IRB)-approved consent forms and protocols. Additional documentation to meet institutional requirements and high-resolution HLA typing (Class I and Class II alleles and CMV status) are available upon request. Heparin is added during collection as an anticoagulant. Contact techsupport@stemcell.com for donor specifications (BMI category, smoking status, ethnicity, etc.). Donors are screened for HIV-1, HIV-2, hepatitis B, and hepatitis C. Certain products are only available in select territories.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Skin, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC MRC-5; Lung Fibroblast; Human (Homo sapiens)
MRC-5 is a diploid cell line d in the production of vaccines, including hepatitis A, polio, and MCR-5, and is made up of fibroblasts isolated from the lung tissue derived from a White, male, 14-week-old embryo by J.P. Jacobs in 1966. The cells are capable of 42 to 46 population doublings.
Discovery Life Sciences Corning Gentest™ Mouse (CD-1) Pooled Liver Microsomes, Male, 0.5 mL
Tissue fractions from human and animal livers represent an important tool in preclinical metabolism studies for predicting the toxicity and pharmacokinetic properties of a drug compound. Liver microsomes from humans and animal species play an important role in evaluating drug compounds for metabolic stability, reactive metabolites, drug-drug interactions, reaction phenotyping, and metabolite identification.
Cellular Dynamics International CARDIOMYOCYTES DIFFERENTIATED
Cardiomyocytes differentiated from human iPS cells, frozen
Eurofins Discoverx ChemiScreen SST5 Somatostatin Receptor Membrane Preparation, 1 vial. (HTS139M)
The ChemiScreen SST5 Somatostatin Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of SSTR5 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.