General Cell Lines and Cell Cultures
Eurofins Discoverx ChemiScreen P2Y11 Purinergic Receptor Stable Cell Line, 2 vials. (HTS213C)
The ChemiScreen P2Y11 Purinergic Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. ATP) based activation of P2RY11 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses P2RY11 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of P2RY11, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Postcentral Gyrus, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
ATCC Quantitative Synthetic; Chlamydia trachomatis; LGV Type 2 DNA
Quantitative Synthetic Chlamydia trachomatis LGV Type 2 DNA can be used for assay development, verification, and validation as well as monitoring of day-to-day test variation and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load. Preparation includes fragments from MOMP, 16S rRNA, pmpH, and dnaB regions.
ACROBiosystems HEK293/Human ASGR1&ASGR2 Stable Cell Line
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (GalNAc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2).
ATCC Quantitative Genomic DNA from; Eubacterium nodatum; Strain: BPI D6 A-5
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine bacterial load.
ATCC Marinobacter nauticus; Strain VT8; genomic DNA
Genomic DNA isolated from Marinobacter nauticus strain VT8 (ATCC 700491). This product can be used in PCR and other molecular biology applications.
Biochain Institute Inc Frozen Tissue Section - Human Adult Normal: Lung, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Brain: Olfactory ( region), 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Eurofins Discoverx ChemiScreen SST3 Somatostatin Receptor Stable Cell Line, 2 vials. (HTS171C)
The ChemiScreen SST3 Somatostatin Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. somatostatin) based activation of SSTR3 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses SSTR3 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of SSTR3, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC HT 1197; Urinary Bladder Carcinoma; Human (Homo sapiens)
HT-1197 is a cell isolated from the urinary bladder of a White, 44-year-old, male with carcinoma. This cell line was deposited by S Rasheed and can be used for immuno-oncology research.
ABclonal Technology Dopamine Transporter/SLC6A3 Rabbit pAb
This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3 UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
![Biolegend Alexa Fluor 488 anti-α Smooth Muscle Actin [1A4]; Isotype: Mouse IgG2a, κ; Reactivity: Human, Mouse; Apps: IHC-P, ICC; Size: 25 μg](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502723719.png-250.jpg)
Biolegend Alexa Fluor 488 anti-α Smooth Muscle Actin [1A4]; Isotype: Mouse IgG2a, κ; Reactivity: Human, Mouse; Apps: IHC-P, ICC; Size: 25 μg
Alexa Fluor 488 anti-α Smooth Muscle Actin [1A4]; Isotype: Mouse IgG2a, κ; Reactivity: Human, Mouse; Apps: IHC-P, ICC; Size: 25 μg
ATCC Paeniclostridium sordellii
Paeniclostridium sordellii strain 211 [NCIB 10717] is a bacterial type strain that can be used as a quality control strain for API, BBL, IDS, VITEK, and MicroScan [Reg TM] products.
Eurofins Discoverx ChemiScreen CysLT2 Leukotriene Receptor Stable Cell Line, 2 vials. (HTS088C)
The ChemiScreen CysLT2 Leukotriene Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. leukotriene) based activation of CYSLTR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CYSLTR2 alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CYSLTR2, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
Eurofins Discoverx PathHunter C2C12 TACR1 β-Arrestin Cell Line, 2 vials. (93-0344C7)
The PathHunter TACR1 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. [ligand]) based activation of TACR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged TACR1 and EA-tagged β-Arrestin-2. Activation of TACR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.